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Urinary Monoamine Oxidase Inhibitor and Benzodiazepine Withdrawal

Published online by Cambridge University Press:  29 January 2018

H. Petursson
Affiliation:
Institute of Psychiatry, De Crespigny Park, Denmark Hill, London SE5 8AF
S. K. Bhattacharya
Affiliation:
Bernhard Baron Memorial Research Laboratories and Institute of Obstetrics and Gynaecology, Queen Charlotte's Hospital, Goldhawk Road, London W6 0XG
Vivette Glover
Affiliation:
Bernhard Baron Memorial Research Laboratories and Institute of Obstetrics and Gynaecology, Queen Charlotte's Hospital, Goldhawk Road, London W6 0XG
M. Sandler
Affiliation:
Bernhard Baron Memorial Research Laboratories and Institute of Obstetrics and Gynaecology, Queen Charlotte's Hospital, Goldhawk Road, London W6 0XG
M. H. Lader
Affiliation:
Institute of Psychiatry, De Crespigny Park, Denmark Hill, London SE5 8AF

Summary

A characteristic withdrawal reaction following the cessation of long-term benzodiazepine treatment in seven patients was accompanied by a significant increase in output of urinary monoamine oxidase inhibitor. This finding provides further support for the concept that the urinary inhibitor excretion pattern may be related to stress or anxiety.

Type
Research Article
Copyright
Copyright © The Royal College of Psychiatrists 

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