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Urinary 17-Ketosteroid Fractionation in Depression: a Preliminary Report

Published online by Cambridge University Press:  29 January 2018

J. Mendels
J. Mendels*
Affiliation:
Affective Diseases Research Unit, Department of Psychiatry, University of Pennsylvania and Veterans Administration Hospital, University and Woodland Avenues, Philadelphia, Pennsylvania 19104
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Extract

Most of the studies of steroid metabolism in depression conducted thus far have been of glucocorticoid activity. Rubin and Mandell (31) reviewed adrenal cortisol production in pathological emotional states and concluded that there was ample evidence of heightened cortical release of 17-hydroxycorticoids (17 OHGS) in depression.

Type
Biochemical Studies
Information
The British Journal of Psychiatry , Volume 115 , Issue 522 , May 1969 , pp. 581 - 585
Copyright
Copyright © Royal College of Psychiatrists, 1969 

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