Hostname: page-component-586b7cd67f-tf8b9 Total loading time: 0 Render date: 2024-11-24T08:03:10.419Z Has data issue: false hasContentIssue false

Treatment of Cocaine Abuse with Monoamine Oxidase Inhibitors

Published online by Cambridge University Press:  02 January 2018

Colin Brewer*
Affiliation:
The Stapleford Centre, 25a Eccleston Street, London SW1W 9NP

Abstract

A cocaine-abusing patient was treated with phenelzine and tranylcypromine, under supervision, as deterrent drugs; other medical and psychological treatments had fated. When he eventually risked using cocaine there was no hypertensive reaction. Nevertheless, the deterrent effect seemed helpful in breaking his pattern of cocaine use, as confirmed by hair analysis for cocaine.

Type
Brief Reports
Copyright
Copyright © The Royal College of Psychiatrists 

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Baumgartner, W. A., Hill, V. A. & Blahd, M. D. (1989) Hair analysis for drugs of abuse. Journal of Forensic Sciences, 34, 14331453.Google Scholar
Blackwell, B. (1963) Hypertensive crisis due to monoamine oxidase inhibitors. Lancet, ii, 849851.CrossRefGoogle Scholar
Brewer, C. (1984) Combining pharmacological antagonists and behavioural psychotherapy in treating addictions: why it is effective but unpopular. British Journal of Psychiatry, 157, 3440.Google Scholar
Chick, J., Gough, K., Falkowski, W., et al (1992) Disulfiram treatment of alcoholism. British Journal of Psychiatry, 161, 8489.Google Scholar
Dackis, C. A., Gold, M. S., Sweeney, D. R., et al (1987) Single-dose bromocriptine reverses cocaine craving. Psychiatric Research, 20, 261264.Google Scholar
Edwards, G. (1987) The Treatment of Drinking Problems: A Guide for the Helping Professions (2nd edn), pp. 274276. Oxford: Blackwell.Google Scholar
Golwyn, D. (1988) Cocaine abuse treated with phenelzine. International Journal of Addiction, 23, 897905.Google Scholar
Heather, N. (1993) Disulfiram treatment for alcohol problems: is it effective and, if so, why? In Treatment Options in Addiction: Medical Management of Alcohol and Opiate Abuse (ed. Brewer, C.), pp. 118. London: Gaskell.Google Scholar
Johnsen, J. & Morland, J. (1991) Disulfiram implant: a double-blind placebo controlled follow-up on treatment outcome. Alcoholism: Clinical and Experimental Research, 15, 532536.Google Scholar
Lowinger, P. & Dobie, S. (1969) What makes the placebo work? Archives of General Psychiatry, 20, 8488.Google Scholar
Resnick, R. & Resnick, E. B. (1986) Psychological issues in the treatment of cocaine abuse. NIDA Research Monograph, 67, 290294.Google Scholar
Submit a response

eLetters

No eLetters have been published for this article.