Hostname: page-component-cd9895bd7-hc48f Total loading time: 0 Render date: 2024-12-18T04:20:06.042Z Has data issue: false hasContentIssue false

Smoking and Malignancy in Schizophrenia

Published online by Cambridge University Press:  29 January 2018

E. Masterson
Affiliation:
University College, Dublin
B. O'Shea*
Affiliation:
St. Brendan's Hospital, Rathdown Road, Dublin 7; University College, Dublin; Royal College of Surgeons in Ireland
*
Correspondence

Summary

It has been suggested that schizophrenic patients have a lower risk of cancer than the general population. We therefore investigated the smoking patterns of 100 current chronic schizophrenic in-patients, and the causes of death in 122 recently deceased schizophrenics. We found that schizophrenics are heavy smokers, and that schizophrenics do die from carcinoma of the bronchus. Proportional mortality rates for all malignancies were not significantly lower in schizophrenics than in the general population but there was a significant absence of cancer of the gastro-intestinal tract. Proportional mortality rates for female mammary carcinoma, pneumonia, and suicide were raised, and that for cerebrovascular disease was low. These differences between schizophrenics and the general population warrant further investigation.

Type
Research Article
Copyright
Copyright © 1984 The Royal College of Psychiatrists 

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Achterberg, J., Collerain, I. & Craig, P. (1978) A possible relationship between cancer, mental retardation and mental disorders. Social and Scientific Medicine, 12, 135–9.Google ScholarPubMed
Armstrong, B. & Doll, R. (1975) Environmental factors and cancer incidence and mortality in different countries, with special reference to dietary practices. International Journal of Cancer, 15, 617–31.CrossRefGoogle ScholarPubMed
Burkitt, D. P. (1971) Epidemiology of cancer of colon and rectum. Cancer, 28, 313.3.0.CO;2-N>CrossRefGoogle Scholar
Craig, T. J. & Lin, S. P. (1981) Cancer and mental illness. Comprehensive Psychiatry, 22, 404–10.Google Scholar
Driscoll, J. S., Melnick, N. R., Quinn, F. R., Lomax, N., Davignon, J. P., Ing, R. Abbott, B. J., Congleton, G. & Dudeck, L. (1978) Psychotropic drugs as potential antitumour agents: a selective screening study. Cancer Treatment Reports, 62, 45.Google Scholar
Graham, S., Schotz, W. & Martino, P. (1972) Alimentary factors in the epidemiology of gastric cancer. Cancer, 30, 927–38.3.0.CO;2-L>CrossRefGoogle ScholarPubMed
Innes, G. & Millar, W. M. (1970) Mortality among psychiatric patients. Scottish Medical Journal, 15, 143–9.Google Scholar
Josephy, H. (1949) Analysis of mortality and causes of death in a mental hospital. American Journal of Psychiatry, 106, 185.CrossRefGoogle Scholar
McMahon, B., Lin, T. M., Lowe, C. R., Mirra, A. P., Ravnihar, B., Salber, E. J., Trichopoulos, D., Valaoras, V. G. & Yuasa, S. (1970) Age at first birth and breast cancer risk. Bulletin of the World Health Organisation, 43, 209.Google Scholar
O'Connor, J. (1982) A national study of smoking and drinking behaviour: social and cultural influences. Health Education Bureau. (With permission).Google Scholar
Odegaard, O. (1952) The excess mortality of the insane. Acta Psychiatrica Scandinavica, 27, 353–67.CrossRefGoogle Scholar
Peller, S. & Stephenson, C. S. (1941) Cancer in the mentally ill. Public Health Reports, 56, 132–49.Google Scholar
Pfeiffer, C. J., (ed) (1979) Gastric Cancer. Etiology and Pathogenesis. New York: Gerard Witzstrock.Google Scholar
Registrar General. (1978) Report on Vital Statistics. Dublin: Central Statistics Office.Google Scholar
Registrar General. (1981) Quarterly Report on Births, Deaths and Marriages and on Infectious Diseases, December quarter 1981 and Yearly summary 1981. Dublin: Central Statistics Office.Google Scholar
Rice, D. (1979) No lung cancer in schizophrenics. British Journal of Psychiatry, 134, 128.Google Scholar
Rivera-Calimlim, L. (1977) The pharmacology and therapeutic application of the phenothiazines. Rational Drug Therapy, 11, 1.Google Scholar
Rothfeld, B. (1959) Comparison of autopsy and clinical diagnosis on psychiatric patients. Diseases of the Nervous System, 20, 406–8.Google Scholar
Royal College of Physicians. (1962) Smoking and Health. Summary and Report of The Royal College of Physicians of London on Smoking in Relation to Cancer of the Lung and Other Diseases. New York: Pitman.Google Scholar
Sachar, E. J. (1967) Corticosteroids in depressive illness: II. Longitudinal psychologic endocrine study. Archives of General Psychiatry, 17, 554.Google Scholar
Schyve, P. M., Smithline, F. & Maltzer, H. Y. (1978) Neuroleptic-induced prolactin level elevation and breast cancer. Archives of General Psychiatry, 35, 1291–301.Google Scholar
Selye, H. (1956) The Stress of Life. New York: McGraw-Hill.Google Scholar
Snow, H. (1983) A Treatise: Practical and Theoretic on Cancers and the Cancer Process. London: J. & A. Churchill.Google Scholar
Surgeon General (1979) Smoking and Health: A Report of the Surgeon General. Washington: U.S. Government Printing Office.Google Scholar
White, M. A. (1929) The social significance of mental disease. Archives of Neurology and Psychiatry, 22, 853.Google Scholar
World Health Organisation. (1978) International Classification of Diseases (9th revision). Geneva: WHO.Google Scholar
Submit a response

eLetters

No eLetters have been published for this article.