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Serum Proteins in Huntington's Chorea

Published online by Cambridge University Press:  29 January 2018

Valerie Cowie
Affiliation:
Psychiatric Genetics Research Unit, Maudsley Hospital, London, S.E.5
D. B. Gammack
Affiliation:
Department of Biochemistry, Institute of Psychiatry, Maudsley Hospital, London, S.E.5

Extract

Huntington's chorea is transmitted by a rare autosomal Mendelian dominant gene. Its hereditary transmission is facilitated by a late onset of the condition in many cases. Often the first signs are not seen until late in the reproductive period, so that it is not uncommon for a patient already to have produced a number of children before the diagnosis is made. On a theoretical basis, 50 per cent. of these offspring are at risk for carrying the gene and consequently for developing the condition themselves.

Type
Research Article
Copyright
Copyright © Royal College of Psychiatrists, 1966 

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