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Serotonin Reuptake Inhibitors, Epilepsy and Myoclonus

Published online by Cambridge University Press:  02 January 2018

Martin Deahl*
Affiliation:
The Medical College of St Bartholomew's Hospital, West Smithfield, London EC1A 7BE
Michael Trimble
Affiliation:
The Institute of Neurology, Queen Square, London WC1N 3BG
*
Department of Psychological Medicine, St Bartholomew's Hospital, West Smithfield, London EC1A 7BE

Abstract

Specific inhibitors of 5-HT reuptake are reported to have lower preconvulsive activity than other antidepressants. A patient with post-traumatic epilepsy who had remained fit-free for many years until she was given the 5-HT reuptake inhibitor fluvoxamine is reported. Changes in serotonergic function may play a more widespread role in the pathophysiology of seizure disorders than hitherto thought.

Type
Brief Reports
Copyright
Copyright © 1991 The Royal College of Psychiatrists 

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