Hostname: page-component-78c5997874-g7gxr Total loading time: 0 Render date: 2024-11-03T00:54:41.153Z Has data issue: false hasContentIssue false
  • English
  • Français

A Serological Study on Mentally Ill Patients

With Particular Reference to the Prevalence of Herpes Virus Infections

Published online by Cambridge University Press:  29 January 2018

Erik Lycke ,
Ragnar Norrby  and
Björn-Erik Roos
Erik Lycke
Affiliation:
Department of Virology, Institute of Medical Microbiology, University of Göteborg, Guldhedsgatan 10B, 413 46 Göteborg, Sweden
Ragnar Norrby
Affiliation:
Department of Virology, Institute of Medical Microbiology, University of Göteborg, Guldhedsgatan 10B, 413 46 Göteborg, Sweden
Björn-Erik Roos
Affiliation:
Department of Virology, Institute of Medical Microbiology, University of Göteborg, Guldhedsgatan 10B, 413 46 Göteborg, Sweden
Get access Rights & Permissions [Opens in a new window]

Extract

It is known that different mental symptoms may occur as early symptoms of acute viral meningoencephalitides. In herpes virus (HSV) infections of the central nervous system (CNS) the appearance of these symptoms is well documented (Juel-Jensen and MacCallum, 1972). The recurrence of psychotic symptoms in cases of recurrent HSV infections has also been described (Shearer and Finch, 1964; Drachman and Adams, 1962). In recent years serological observations of the prevalence of HSV antibodies in patients with psychiatric disorders have suggested a possible association of HSV infections with aggressive behaviour (Cleobury et al., 1971), as well as with psychotic depressions (Rimon and Halonen, 1969).

Type
Research Article
Information
The British Journal of Psychiatry , Volume 124 , Issue 580 , March 1974 , pp. 273 - 279
Copyright
Copyright © Royal College of Psychiatrists, 1974 

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Garlsson, A. (1967). ‘Basic actions of psychoactive drugs.’ Int. J. Neurol., 6, 27–45.Google Scholar
Cleobury, J. R., Skinner, G. R. B., Thouless, M. E., and Wildy, P. (1971). ‘Association between psychopathic disorder and serum antibody to herpes simplex virus (Type 1).’ Brit. med. J., i, 438–9.Google Scholar
Drachman, D. A., and Adams, R. D. (1962). ‘Herpes simplex and acute inclusion-body encephalitis.’ Arch. Neurol., 7, 45–63.Google Scholar
Hill, T. J., Field, H. J., and Roome, A. P. C. (1972). ‘Intra-axonal location of herpes simplex virus particles.’ J. Gen. Virol., 15, 253–5.Google Scholar
Juel-Jenson, B. E., and MacCallum, F. O. (1972). Herpes Simplex, Varicella and Zoster, Clinical Manifestations and Treatment. London: William Heinemann Medical Books.Google Scholar
Kaspenbero, J. G. (1964). ‘Possible antigenic relationship between varicella/zoster virus and herpes simplex virus.’ Arch. ges. Virusforsch., 15, 67–73.Google Scholar
Kristensson, K., Lycke, E., and Sjöstrand, J. (1971). ‘Spread of herpes simplex virus in peripheral nerves.’ Acta Neuropath. (Berl.), 17, 44–53.Google Scholar
Leider, W., Magoffin, R. L., Lennette, F. H., and Leonards, L. N. R. (1965). ‘Herpex simplex virus encephalitis: its possible association with reactivated latent infection.’ New Engl. J. Med., 273, 341–7.Google Scholar
Lycke, E., Modigh, K., and Roos, B.-E. (1970). ‘The monoamine metabolism in virus encephalitides of the mouse. I. Virological and biochemical results.’ Brain Research, 23, 235–46.Google Scholar
Lycke, E., Modigh, K., and Roos, B.-E. (1969). ‘Aggression in mice associated with changes in the monoamine metabolism of the brain.’ Experientia (Basel), 25, 951–3.Google Scholar
Lycke, E. and Roos, B.-E. (1972). ‘The monoamine metabolism in virus encephalitides of the mouse. II. Turnover of monoamines in mice infected with herpes simplex virus.’ Brain Research, 44, 603–13.CrossRefGoogle ScholarPubMed
Lycke, E., Modigh, K. (1972). ‘The monoamine metabolism in virus encephalitides of the mouse. III. Evidence for induction of excitation by increased activity of adrenergic neurons in herpes simplex virus infection.’ In press.Google Scholar
Lycke, E., Modigh, K. (1971). Results presented at the second meeting of Scandinavian Virologists, Lammi.Google Scholar
Nordenfelt, E., Andrén-Sandbero, M., Lundquist, A., and Henrikson, H. (1971). ‘Persistence of Australia (Au-) antigen among patients in an institution for mentally retarded and its relation to chronic liver disease.’ Scand. J. inf. Dis., 3, 103–7.Google Scholar
Olson, L. C., Buescher, F. L., Artenstein, M. S., and Parkman, P. D. (1967). ‘Herpes virus infection of the central nervous system.’ New Engl. J. Med., 277, 1271–7.Google Scholar
Prince, A. M. (1968). ‘An antigen detected in the blood during the incubation period of hepatitis.’ Proc. Nat. Acad. Sci. USA, 60, 814–21.Google Scholar
Rimon, R., and Halonen, P. (1969). ‘Herpes simplex virus infection and depressive illness.’ Dis. nerv. Syst., 30, 338–40.Google Scholar
Ross, C. A. C., Subak-Sharpe, J. H., and Ferry, P. (1965). ‘Antigenic relationship of varicella-zoster and herpes simplex.’ Lancet, ii, 708–11.Google Scholar
Sever, J. L. (1962). ‘Application of a microtechnique to viral serological investigations.’ J. Immunol., 88, 320–9.Google Scholar
Shaw, D. M., Camps, F. E., and Eccleston, E. G. (1967). ‘5-hydroxytryptamine in the hind-brain of depressive suicides.’ Brit. J. Psychiat., 113, 1407–11.Google ScholarPubMed
Shearer, M. L., and Finch, S. M. (1964). ‘Periodic organic psychosis associated with recurrent herpes simplex.’ N. Engl. J. Med., 271, 494–7.Google Scholar
Stevens, J. G., and Cook, M. L. (1971). ‘Latent herpes virus in spinal ganglia of mice.’ Science, 173, 843–5.Google Scholar
Stevens, J. G., Nesburn, A. B., and Cook, M. L. (1972). ‘Latent herpes simplex virus from the trigeminal ganglia of rabbits with recurrent eye infection.’ Nature New Biology, 235, 216–7.Google Scholar
Szmuness, W., Pick, R., and Prince, A. M. (1970). ‘The serum hepatitis virus specific antigen (SH): A preliminary report of epidemiologic studies in an institution for the mentally retarded.’ Amer. J. Epid., 92, 51–61.Google Scholar
Wadsworth, C. (1957). ‘A slide microtechnique for the analysis of immune precipitates in gel.’ Int. Arch. Allergy appl. Immunol., 10, 355–9.Google Scholar
Wentworth, , Berttina, B., and Alexander, E. R. (1971). ‘Seroepidemiology of infections due to members of the herpes virus group.’ Amer. J. Epid., 94, 496–507.Google Scholar
Submit a response

eLetters

No eLetters have been published for this article.