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The Scottish First Episode Schizophrenia Study

VI. Computerised Tomography Brain Scans in Patients and Controls

Published online by Cambridge University Press:  02 January 2018

H. L. MacDonald ,
J. J. K. Best ,
Robin G. McCreadie ,
David H. Wiles ,
Stewart M. Grant ,
John W. Moore ,
George T. Crocket ,
Zahid Mahmood ,
Martin G. Livingston  and
James A. G. Watt
...Show all authors
H. L. MacDonald
Affiliation:
Eastern General Hospital, Edinburgh EH6 7LN
J. J. K. Best
Affiliation:
Department of Medical Radiology, University of Edinburgh, Edinburgh Royal Infirmary, Edinburgh EH3 9YW
Robin G. McCreadie
Affiliation:
Gartloch Hospital, Gartcosh, Glasgow G69 8EJ
David H. Wiles
Affiliation:
Gartloch Hospital, Gartcosh, Glasgow G69 8EJ
Stewart M. Grant
Affiliation:
Gartloch Hospital, Gartcosh, Glasgow G69 8EJ
John W. Moore
Affiliation:
Gartloch Hospital, Gartcosh, Glasgow G69 8EJ
George T. Crocket
Affiliation:
Gartnavel Royal Hospital, Glasgow G12 0YN
Zahid Mahmood
Affiliation:
Gartnavel Royal Hospital, Glasgow G12 0YN
Martin G. Livingston
Affiliation:
Leverndale Hospital, Glasgow G53 7TU
James A. G. Watt
Affiliation:
Leverndale Hospital, Glasgow G53 7TU
J. G. Greene
Affiliation:
Leverndale Hospital, Glasgow G53 7TU
Peter W. Kershaw
Affiliation:
Leverndale Hospital, Glasgow G53 7TU
Norman A. Todd
Affiliation:
Royal Edinburgh Hospital, Edinburgh EH10 5HF
Angus M. Scott
Affiliation:
Royal Edinburgh Hospital, Edinburgh EH10 5HF
James A. T. Dyer*
Affiliation:
Grove, Wantage, Oxon
John Loudon
Affiliation:
Grove, Wantage, Oxon
Alistair E. Philip
Affiliation:
Grove, Wantage, Oxon
The Scottish Schizophrenia Research Group
Affiliation:
Crichton Royal Hospital, Dumfries DG1 4TG
*
∗Correspondence
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Abstract

This is the initial report of a prospective study by computerised tomography brain scan of first episode schizophrenia. Twenty-seven patients who met Research Diagnostic Criteria for schizophrenia were compared with volunteer controls on ventricular: brain ratio, sulcal: brain volume ratio, and the widths of third ventricle and Sylvian and interhemispheric fissures. The results provide evidence that sulcal enlargement, but not ventricular abnormalities, may be detected at first admission for schizophrenic illness, and are discussed in relation to findings from other studies.

Type
Papers
Information
The British Journal of Psychiatry , Volume 154 , Issue 4 , April 1989 , pp. 492 - 498
Copyright
Copyright © Royal College of Psychiatrists, 1989 

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