Hostname: page-component-cd9895bd7-q99xh Total loading time: 0 Render date: 2024-12-24T13:22:53.308Z Has data issue: false hasContentIssue false

Schizophrenic and Manic Brains in Nigerians Computerised Tomography Findings

Published online by Cambridge University Press:  02 January 2018

Jude U. Ohaeri*
Affiliation:
Department of Psychiatry, College of Medicine, University of Ibadan, Ibadan, Nigeria
Abiodun O. Adeyinka
Affiliation:
Department of Radiology, College of Medicine, University of Ibadan, Ibadan, Nigeria
Solomon N. Enyidah
Affiliation:
Department of Psychiatry, College of Medicine, University of Ibadan, Ibadan, Nigeria
Benjamin O. Osuntokun
Affiliation:
Department of Neurology, College of Medicine, University of Ibadan, Ibadan, Nigeria
*
Dr Ohaeri, Department of Psychiatry, University College Hospital, Ibadan, Oyo State, Nigeria

Abstract

Background

We highlight the profile of brain computerised tomography (CT) measures among Nigerian psychiatric patients for comparison with findings from developed countries, and study of the relationship between CT values and clinical variables.

Method

Seven brain ventricle measures of 50 schizophrenic patients, 14 manic patients, and 41 healthy control subjects were compared.

Results

Patients had a significantly higher mean Sylvian fissure area. The third ventricle of schizophrenic patients was significantly larger than those of control subjects. CT measures were not significantly correlated with duration of illness.

Conclusion

The so-called functional psychotic states are most probably associated with nonspecific brain abnormality.

Type
Papers
Copyright
Copyright © Royal College of Psychiatrists, 1995 

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

American Psychiatric Association (1987) Diagnostic and Statistical Manual of Mental Disorders (3rd edn) (DSM–III). Washington, DC: APA.Google Scholar
Andreasen, N. C. (1982) Negative symptoms in schizophrenia: definition and reliability. Archives of General Psychiatry, 39, 784788.CrossRefGoogle ScholarPubMed
Andreasen, N. C., Oslen, S. A., Dennert, J. W., et al (1982) Ventricular enlargement in schizophrenia: relationship to positive and negative symptoms. American Journal of Psychiatry, 139, 292296.Google ScholarPubMed
Jablensky, A., Sartorius, N., Ernberg, G., et al (1992) Schizophrenia; manifestations, incidence, and course in different cultures: a World Health Organization ten-country study. Psychological Medicine (Monograph Supplement), 20.CrossRefGoogle Scholar
Johnstone, E. C., Crow, T. J., Frith, C. D., et al (1976) Cerebral ventricular size and cognitive impairment in chronic schizophrenia. Lancet, ii, 924926.CrossRefGoogle Scholar
Makanjuola, R. O. A. (1985) Recurrent unipolar manic disorder in the Yoruba Nigerian: further evidence. British Journal of Psychiatry, 147, 434437.CrossRefGoogle ScholarPubMed
Ohaeri, J. U. (1992) Age at onset in a cohort of schizophrenics in Nigeria. Acta Psychiatrica Scandinavica, 86, 332334.CrossRefGoogle Scholar
Ohaeri, J. U. (1993) Long-term outcome of treated schizophrenia in a Nigerian cohort. Journal of Nervous and Mental Disorders, 181, 514516.CrossRefGoogle Scholar
Pearlson, G. D., Kim, W. S., Kubos, K., et al (1989) Ventricle-brain ratio, computed tomographic density and brain area in 50 schizophrenics. Archives of General Psychiatry, 46, 690697.CrossRefGoogle ScholarPubMed
Pfefferbaum, A. & Zipursky, R. B. (1991) Neuroimaging studies of schizophrenia. Schizophrenia Research, 4, 193208.CrossRefGoogle ScholarPubMed
Rieder, R. O., Mann, L. S., Weinberger, D. R., et al (1983) Computed tomographic scans in patients with schizophrenia, schizoaffective and bipolar affective disorder. Archives of General Psychiatry, 40, 735739.CrossRefGoogle ScholarPubMed
Wing, J. K., Cooper, J. E. & Sartorius, N. (1974) The Measurement and Classification of Psychiatric Symptoms. London: Cambridge University Press.Google Scholar
Submit a response

eLetters

No eLetters have been published for this article.