Hostname: page-component-cd9895bd7-jn8rn Total loading time: 0 Render date: 2024-12-26T18:38:32.287Z Has data issue: false hasContentIssue false

The Relationship Between the Effect of Lactate Infusion on Anxiety States, and their Amelioration by Carbon Dioxide Inhalation

Published online by Cambridge University Press:  29 January 2018

M. T. Haslam*
Affiliation:
Clifton Hospital, York

Extract

Anxiety is perhaps one of the commonest and most disabling symptoms in medicine, yet its satisfactory alleviation has been elusive.

Work by Kluver and Bucy (1939) suggested that the amygdala generated anxiety, the function of the hippocampus being to decrease it. The hypothalamus appears to organize the level of arousal through the amygdala.

Type
Research Article
Copyright
Copyright © Royal College of Psychiatrists, 1974 

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Bain, J. A. & Kleine, J. R. (1948) Effect of CO2 concentration on brain lactate. Federation Proc., 7, 145.Google Scholar
Birkmeyer, W. (1970) Correlations between muscle tone and psyche. International Symposium, St. Monty, 16 January, p. 29.Google Scholar
Cohen, M. B. & White, P. D. (1950) Life situations, emotions, and neurocirculatory aesthenia. Ass. Research. nerv. ment. Dis. Proc., 29, 832–69.Google Scholar
Fox, R. H. & Edholm, O. G. (1963) Nervous control of the cutaneous circulation. British Medical Bulletin, 19, 100.CrossRefGoogle ScholarPubMed
Gellhorn, E. (1953) The physiological basis of CO2 therapy in psychoneurosis. Journal of Mental Science, 99, 357–73.CrossRefGoogle Scholar
Kelly, D., Mitchell-Heggs, N. & Sherran, D. (1971) Anxiety and the effects of sodium lactate, assessed clinically and physiologically. British Journal of Psychiatry, 119, 129–41.Google Scholar
Kluver, H. & Bucy, P. C. (1939) Arch. Neurol. Psychiat., 42, 979.Google Scholar
La Verne, A. A. (1953) Rapid coma technique of carbon dioxide inhalation therapy. Dis. nerv. Syst., 14, 141.Google Scholar
Meduna, L. J. (1956) Carbon Dioxide Therapy. Springfield, Illinois: C. C. Thomas.Google Scholar
Pitts, F. N. Jnr. & McClure, J. R. J. (1967) Lactate metabolism in anxiety neurosis. New Eng. Jour. Med., 277, 1329–31.Google Scholar
Snaith, R. P. (1968) A clinical investigation of phobias. British Journal of Psychiatry, 114, 511, 673–98.Google Scholar
Wallace, R. K. (1972) American Journal of Psychiatry, 221, 795.Google Scholar
Wolpe, J. (1958) Psychotherapy by Reciprocal Inhibition. California: Stanford University Press.Google Scholar
Submit a response

eLetters

No eLetters have been published for this article.