Hostname: page-component-745bb68f8f-b95js Total loading time: 0 Render date: 2025-01-27T17:16:37.929Z Has data issue: false hasContentIssue false
  • English
  • Français

Polydactyly and psychosis

Five cases of co-occurrence

Published online by Cambridge University Press:  02 January 2018

Alastair G. Cardno ,
Kieran C. Murphy ,
Lisa A. Jones ,
Jonathon Gray ,
Peter McGuffin ,
Michael J. Owen  and
Andrew M. Cobb
Alastair G. Cardno*
Affiliation:
University of Wales College of Medicine, Cardiff
Kieran C. Murphy
Affiliation:
University of Wales College of Medicine, Cardiff
Lisa A. Jones
Affiliation:
University of Wales College of Medicine, Cardiff
Jonathon Gray
Affiliation:
University of Wales College of Medicine, Cardiff
Peter McGuffin
Affiliation:
University of Wales College of Medicine, Cardiff
Michael J. Owen
Affiliation:
University of Wales College of Medicine, Cardiff
Andrew M. Cobb
Affiliation:
Tower Hamlets Healthcare NHS Trust, The Royal London Hospital, London
*
Dr A. Cardno. Department of Psychological Medicine. University of Wales College of Medicine. Heath Park, Cardiff CF4 4XN. Tel: 01222 743058: Fax: 01222 747839
Get access Rights & Permissions [Opens in a new window]

Abstract

Background

Abnormalities presumed to occur during foetal life have been associated with schizophrenia. Polydactyly is a developmental abnormality but no previous association has been reported between Polydactyly and functional psychotic illness.

Method

Individuals with both Polydactyly and a functional psychosis were ascertained during a study of familial schizophrenia.

Results

Five such individuals were ascertained in the course of assessing 234 individuals with familial psychosis, giving a rate of Polydactyly in the sample of around 10 times the general population rate.

Conclusions

This study provides preliminary evidence that Polydactyly is over-represented in individuals with familial schizophrenia and related psychotic illnesses.

Type
Preliminary Report
Information
The British Journal of Psychiatry , Volume 172 , Issue 2 , February 1998 , pp. 184 - 185
Copyright
Copyright © 1998 The Royal College of Psychiatrists 

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

American Psychiatric Association (1994) Diagnostic and Statistical Manual of Mental Disorders (4th edn) (DSM–IV). Washington. DC: APA.Google Scholar
Murray, R. M. (1994) Neurodevelopmental schizophrenia: the rediscovery of dementia praecox. British Journal of Psychiatry, 165 (suppl. 25), 6–12.Google Scholar
Nelson, W. E. Behrman, R. E. Kliegman, R. M. et al (1996) Nelson Textbook of Paediatrics (15th edn), p. 1923. Philadelphia, PA: Saunders.Google Scholar
O'Callaghan, E. Larkin, C. Kinsella, A. et al (1991) Familial, obstetric and other clinical correlates of minor physical anomalies in schizophrenia. American Journal of Psychiatry, 148, 479–483.Google ScholarPubMed
Taeusch, H. W. Ballard, R. A. & Avery, M. E. (1991) Schaffer and Avery's Diseases of the Newborn (6th edn). Philadelphia, PA: Saunders.Google Scholar
Submit a response

eLetters

No eLetters have been published for this article.