Hostname: page-component-586b7cd67f-2plfb Total loading time: 0 Render date: 2024-12-03T00:37:59.498Z Has data issue: false hasContentIssue false

Parent-Child Concordance with Respect to Sex and Diagnosis in Schizophrenia and Manic-Depressive Psychosis

Published online by Cambridge University Press:  29 January 2018

Anne Powell
Affiliation:
Department of Mental Health, University of Aberdeen, Aberdeen, AB9 2ZX
Nancy M. Thomson
Affiliation:
Department of Psychology, University of Aberdeen, Aberdeen, AB9 2ZX
David J. Hall
Affiliation:
Department of Mental Health, University of Aberdeen, Aberdeen, AB9 2ZX
Linda S. Wilson
Affiliation:
Department of Mental Health, University of Aberdeen, Aberdeen, AB9 2ZX

Extract

In the search for an explanation of the aetiology of psychiatric illness, the study of the family as a unit for psychiatric research is becoming increasingly necessary. That family members resemble one another in many respects seems an intuitively correct idea. Children resemble their parents in both physical attributes and temperament; the former is mainly attributed to heredity and the latter to an interaction of heredity and social learning. Previous psychiatric studies of the family have indicated two areas for further investigation: firstly, sex concordance, and secondly diagnostic concordance among psychiatrically ill first degree relatives. The literature relating to these areas is abundant, and the main conclusions are summarized below.

Type
Research Article
Copyright
Copyright © Royal College of Psychiatrists, 1973 

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Baldwin, J. A., Innes, G., Millar, W. M., Sharp, G. A., and Dorricott, N. (1965). ‘A psychiatric case register in North East Scotland.’ Brit. J. prev. soc. Med., 19, 38.Google ScholarPubMed
Böök, J. A. (1953). ‘Schizophrenia as a gene mutation.’ Acta Genetica, 4, 133–9.Google Scholar
Cammer, L. (1969). ‘Schizophrenic children of manic depressive parents.’ Dis. nerv. Syst., 31, 177–80.Google Scholar
Elsässer, G. (1952). Die Nachkommen geisteskranken Elternpaare. New York: Stechen and Hoffner.Google Scholar
Gottesman, I. I., and Shields, J. (1966). ‘Schizophrenia in twins: 16 years consecutive admissions to a psychiatric clinic’ Brit. J. Psychiat., 112, 809–18.Google Scholar
Hall, D. J., Robertson, N. C., Dorricott, N., Olley, P. G., and Millar, W. M. (1973). ‘The North-East Scotland Psychiatric Case Register—the second phase.’ In press.Google Scholar
Kallmann, F.J. (1946). The Genetics of Schizophrenia. New York: J. J. Augustin.Google Scholar
Kallmann, F.J. (1953). Heredity in Health and Mental Disorders. New York: Norton.Google Scholar
Kringlen, E. (1968). ‘An epidemiological-clinical twin study on schizophrenia’, in The Transmission of Schizophrenia (Rosenthal, D., and Kety, S.). Pergamon Press.Google Scholar
McKusick, V. A. (1969). Human Genetics. 2nd edition. Prentice Hall Inc. Google Scholar
Robertson, N. C., Baldwin, J. A., and Hall, D. J. (1971). ‘Methods of record linkage.’ J. chron. Dis., 24, 1 5969.Google Scholar
Robertson, N. C., Hall, D. J., and Wilson, L. S. (1973). ‘Methods of of family record linkage using reliable information.’ In preparation.Google Scholar
Rosanoff, A. J., Handy, I. M., and Plesset, I. R. (1935). ‘The etiology of manic depressive syndromes with special reference to their occurrence in twins.’ Amer. J. Psychiat., 91, 725–62.Google Scholar
Rosenthal, D. (1962). ‘Familial concordance by sex with respect to schizophrenia.’ Psychol. Bull., 59, 401–21.Google Scholar
Rosenthal, D. (1970). Genetic Theory and Abnormal Behavior. McGraw Hill.Google Scholar
Schulz, B. (1940). ‘Erkrankungsalter schizophrenen Eltern und Kinder.’ Zeitschr. Neurol. Psychiat., 168, 709–21.Google Scholar
Slater, E. (1953). Psychotic and Neurotic Illnesses in Twins. Medical Research Council. Spec. Rep. Serv. No. 278, 1385.Google Scholar
Slater, E. (1968). ‘a review of earlier evidence on genetic factors in schizophrenia’, in The Transmission of Schizophrenia (eds. Rosenthal, D., and Kety, S. S.). Pergamon Press.Google Scholar
Stern, C. (1960). Principles of Human Genetics. San Francisco: Freeman.Google Scholar
Winokur, G., and Tanna, V. (1969). ‘Possible role of X-linked dominant factor in manic depressive disease.’ Dis. nerv. Syst., 30, 89.Google Scholar
Submit a response

eLetters

No eLetters have been published for this article.