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Orofacial Dyskinesia in Down's Syndrome

Published online by Cambridge University Press:  02 January 2018

Timothy G. Dinan
Affiliation:
Department of Psychiatry, Trinity College Medical School, St James's Hospital, Dublin
Theresa Golden
Affiliation:
St Loman's Hospital, Dublin

Abstract

Of 54 patients aged 30–60 years with a diagnosis of Down's syndrome, 38 had evidence of orofacial dyskinesia, assessed using the AIMS. There was a strong relationship between the presence of such movements and the severity of mental handicap. No relationship was found between abnormal movements and age. None of the patients had previously taken neuroleptic medication.

Type
Brief Reports
Copyright
Copyright © The Royal College of Psychiatrists 

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References

American Psychiatric Association (1980) Diagnostic and Statistical Manual of Mental Disorders (3rd edn) (DSM–III). Washington, DC: APA.Google Scholar
Dinan, T. G. & Kohen, D. (1989) Tardive dyskinesia in bipolar affective disorder: relationship to lithium therapy. British Journal of Psychiatry, 155, 5558.Google Scholar
Famuyiwa, O. D., Eccleston, D., Donaldson, A. A., et al (1979) Tardive dyskinesia and dementia. British Journal of Psychiatry, 135, 500504.Google Scholar
Gualtieri, C. T., Schroeder, S. R., Hicks, R. E., et al (1986) Tardive dyskinesia in young mentally retarded individuals. Archives of General Psychiatry, 43, 335340.Google Scholar
Guy, W. (1976) ECDEU Assessment Manual for Psychopharmacology. Washington, DC: DHEW.Google Scholar
Hachinski, V. C., Lliff, L. D., Zilkha, E., et al (1975) Cerebral blood flow in dementia. Archives of Neurology, 32, 632637.Google Scholar
Kalachnik, J. E. (1983) Tardive dyskinesia and the mentally retarded. In Advances in Mental Retardation and Developmental Disabilities; A Review (ed. S. Breuning). Connecticut: JAI Press.Google Scholar
Klawans, H. L. & Barr, A. (1982) Prevalence of spontaneous lingual-facial-buccal dyskinesias in the elderly. Neurology, 32, 558559.Google Scholar
O'Keane, V. & Dinan, T. G. (1990) Orofacial dyskinesia and senile dementia of the Alzheimer type. International Journal of Geriatric Psychiatry (in press).Google Scholar
Oliver, C. & Holland, A. (1986) Down's syndrome and Alzheimer's disease: a review. Psychological Medicine, 16, 307322.Google Scholar
St Georoe-Hyslop, P., Tanzi, R. & Polinski, R. (1987) The genetic defect causing familial Alzheimer's disease maps on chromosome 21. Science, 235, 885889.Google Scholar
Struve, F. A. & Willner, A. A. E. (1983) Cognitive dysfunction in tardive dyskinesia. British Journal of Psychiatry, 143, 597600.Google Scholar
Waddington, J. L. (1987) Tardive dyskinesia in schizophrenia and other disorders: associations with ageing, cognitive dysfunction and structural brain pathology in relation to neuroleptic exposure. Human Psychopharmacology, 2, 1122.Google Scholar
Waddington, J. L. & Youssef, H. A. (1986) Involuntary movements and cognitive dysfunction in late onset schizophrenic outpatients. Irish Medical Journal, 79, 347350.Google Scholar
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