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Nuclear Magnetic Resonance (NMR) II. Imaging in Dementia

Published online by Cambridge University Press:  29 January 2018

J. A. O. Besson ,
F. M. Corrigan ,
E. Iljon Foreman ,
L. M. Eastwood ,
F. W. Smith  and
G. W. Ashcroft
J. A. O. Besson*
Affiliation:
Department of Mental Health, University of Aberdeen
F. M. Corrigan
Affiliation:
Department of Mental Health, University of Aberdeen
E. Iljon Foreman
Affiliation:
Department of Mental Health, University of Aberdeen
L. M. Eastwood
Affiliation:
Department of Biomedical Physics & Bioengineering, University of Aberdeen. Now at M & D Technology Ltd., Whitemyres Avenue, Aberdeen
F. W. Smith
Affiliation:
Aberdeen Royal Infirmary
G. W. Ashcroft
Affiliation:
University of Aberdeen
*
∗Correspondence
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Summary

Proton NMR imaging of the brain is rapidly becoming established as a useful investigative tool in medicine. This paper examines the usefulness of the NMR parameters—spin-lattice relaxation time (T1) and proton density (PD)—in differentiating groups of patients with senile dementia of Alzheimer type (SDAT) and multi-infarct dementia (MID) from each other, and from elderly controls. T1 values increase with severity of dementia. NMR parameters may also be of use in localising regions of brain damage.

Type
Research Article
Information
The British Journal of Psychiatry , Volume 146 , Issue 1 , January 1985 , pp. 31 - 35
Copyright
Copyright © 1985 The Royal College of Psychiatrists 

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References

Bondareff, W., Baldry, R. & Levy, R. (1981) Quantitative computed tomography in senile dementia. Archives of General Psychiatry, 38, 1365–1368.CrossRefGoogle ScholarPubMed
Corsellis, J. N. A. (1969) The pathology of dementia. British Journal of Hospital Medicine, 2, 695–702.Google Scholar
Farbas, T., Ferris, S. H., Wolf, A. P., De Leon, M. J., Christman, D. R., Resiberg, G., Alain, A., Fowler, J. S., George, A. E. & Reivich, M. (1982) 18F-Deoxy-2-fluoro-D-glucose as a tracer in the positron emission tomographic study of senile dementia. American Journal of Psychiatry. 139, 352–353.Google Scholar
Ford, C. V. & White, S. (1981) Computerised axial tomograms and dementia in elderly patients. Journal of Gerontology, 36, 164–169.CrossRefGoogle ScholarPubMed
Glen, A. I. M. & Christie, J. E. (1979) Early diagnosis of Alzheimer's Disease: working definitions for clinical and laboratory criteria. In Alzheimer's Disease: Early Recognition of Potentially Reversible Deficits (eds. Glen, A. I. M. & Whalley, L. J.). Edinburgh: Churchill Livingstone.Google Scholar
Hachinski, V. C. (1975) Cerebral blood flow in dementia. Archives of Neurology, 32, 632–637.CrossRefGoogle ScholarPubMed
Hutchison, J. M. S., Edelstein, W. A. & Johnson, G. (1980) A whole body NMR imaging machine. Journal of Physics E: Scientific Instruments, 13, 947–955.CrossRefGoogle Scholar
Johnson, G., Hutchison, J. M. S. & Eastwood, L. M. (1982) Instrumentation for NMR spin-warp imaging. Journal of Physics E: Scientific Instruments, 15, 74–79.CrossRefGoogle Scholar
Kahn, R. L., Goldfarb, A. I., Pollack, M. & Peck, A. (1960) Brief objective measures for the determination of mental status in the aged. American Journal of Psychiatry, 117, 326–328.CrossRefGoogle ScholarPubMed
Lauterbur, P. (1973) Image formation by induced local interactions: examples exploring nuclear magnetic resonance. Nature, 242, 190–191.CrossRefGoogle Scholar
Mattis, S. (1976) Mental status examination for organic mental syndrome in the elderly patient. Geriatric Psychiatry (eds. Bellack, L. E. & Karasut, T. B.). New York: Grune & Stratton.Google Scholar
Nagy, Z., Nagy, N. & Lustyik, G. (1982) Protein and water contents of ageing brain. Experimental Brain Research, Suppl. 5, 118–121. Berlin—Heidelberg: Springer-Verlag.Google Scholar
Redpath, T. W. & Hutchison, J. M. S. (1982) Design of a radio-frequency coil suitable for NMR imaging of heads. Physics in Medicine and Biology, 27, 443–447.CrossRefGoogle Scholar
Soininen, H., Puranen, R. & Riekkinen, P. J. (1982) Computer tomography findings in senile dementia and normal ageing. Journal of Neurology, Neurosurgery and Psychiatry, 45, 50–54.CrossRefGoogle Scholar
Tomlinson, B. E., Blessed, G. & Roth, M. (1970) Observations on the brains of demented old people. Journal of Neurological Science, 11, 205–242.CrossRefGoogle ScholarPubMed
Wilson, R. S., Fox, J. H., Huckman, M. S., Bacon, L. D. & Lobick, J. J. (1982) Computed tomography in dementia. Neurology, 32, 1054–1057.CrossRefGoogle ScholarPubMed
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