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The Measurement of Transmembrane Cation Transport in vivo in Acute Manic Illness

Published online by Cambridge University Press:  02 January 2018

A. J. Wood ,
J. K. Aronson ,
P. J. Cowen  and
D. G. Grahame-Smith
A. J. Wood
Affiliation:
MRC Unit and University Department of Clinical Pharmacology, Radcliffe Infirmary, Woodstock Rd, Oxford 0X2 6HE
J. K. Aronson
Affiliation:
MRC Unit and University Department of Clinical Pharmacology, Radcliffe Infirmary, Woodstock Rd, Oxford 0X2 6HE
P. J. Cowen
Affiliation:
MRC Unit and University Department of Clinical Pharmacology, Radcliffe Infirmary, Woodstock Rd, Oxford 0X2 6HE
D. G. Grahame-Smith
Affiliation:
MRC Unit and University Department of Clinical Pharmacology, Radcliffe Infirmary, Woodstock Rd, Oxford 0X2 6HE
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Abstract

We have used a novel technique to assess the transport of cations across the erythrocyte membrane in vivo in unmedicated patients suffering an acute manic illness. The results show that erythrocyte cation transport via the sodium-pump enzyme Na+,K+-ATPase is increased in manic patients compared with healthy controls.

Type
Papers
Information
The British Journal of Psychiatry , Volume 155 , Issue 4 , October 1989 , pp. 501 - 504
Copyright
Copyright © Royal College of Psychiatrists 1989 

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