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The Long-Term Outcome of Depressive Illness

Published online by Cambridge University Press:  02 January 2018

L. G. Kiloh
Affiliation:
The University of New South Wales
Gavin Andrews*
Affiliation:
Clinical Research Unit for Anxiety Disorders, The University of New South Wales at St Vincent's Hospital
Megan Neilson
Affiliation:
Clinical Research Unit for Anxiety Disorders, The University of New South Wales at St Vincent's Hospital
*
Clinical Research Unit for Anxiety Disorders, 299 Forbes Street, Darlinghurst, NSW 2010, Australia

Abstract

One hundred and forty-five patients with primary depressive illness admitted to a university hospital between 1966 and 1970 were followed up an average of 15 years later. Adequate data were obtained on 133 (92%) of the 145. During the follow-up period, 7% of the 133 had suicided, 12% had remained incapacitated by illness and only 20% had remained continuously well. Patients for whom the index admission was not their first were especially likely to be readmitted during the follow-up period. Patients with endogenous depression, none of whom developed schizophrenia during the follow-up period, were more likely to need readmission than patients with an index diagnosis of neurotic depression. In all other respects the prognosis for the two types of depression was the same, with considerable morbidity evident in both.

Type
Research Article
Copyright
Copyright © Royal College of Psychiatrists, 1988 

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References

Andrews, G., Kiloh, L. G. & Neilson, M. (1973) Patterns of depressive illness: the compatibility of disparate points of view. Archives of General Psychiatry, 29, 670673.CrossRefGoogle ScholarPubMed
Carney, M. W. P., Roth, M. & Garside, R. F. (1965) The diagnosis of depressive syndromes and the prediction of ECT response. British Journal of Psychiatry, 111, 659674.CrossRefGoogle Scholar
Gillespie, R. D. (1929) The clinical differentiation of types of depression. Guy's Hospital Reports, 79.Google Scholar
Kendell, R. E. (1968) The Classification of Depressive Illnesses. London: Oxford University Press.Google Scholar
Kiloh, L. G. & Garside, R. F. (1963) The independence of neurotic depression and endogenous depression. British Journal of Psychiatry, 109, 451463.Google Scholar
Kiloh, L. G., Andrews, G., Bianchi, G. N. & Neilson, M. (1972a) On studying depression. Australian and New Zealand Journal of Psychiatry, 6, 8598.Google Scholar
Kiloh, L. G., Andrews, G., Neilson, M. & Bianchi, G. N. (1972b) The relationship of the syndromes called endogenous and neurotic depression. British Journal of Psychiatry, 121, 183196.CrossRefGoogle ScholarPubMed
Kiloh, L. G., Andrews, G., & Neilson, M. (1974) The influence of diagnosis on the treatment of depressed patients. In Depression in Everyday Practice (ed. Kielholz, O.). Berne: Hans Huber.Google Scholar
Kiloh, L. G., & Garside, R. F. (1977) Depression: a multivariate study of Sir Aubrey Lewis's data on melancholia. Australian and New Zealand Journal of Psychiatry, 11, 149156.CrossRefGoogle ScholarPubMed
Kraepelin, E. (1913) Psychiatrie Vol. 3, 8th edn Leipzig.Google Scholar
Lee, A. S. & Murray, R. M. (1988) The long term outcome of Maudsley depressives. British Journal of Psychiatry, 153, 741751 Google Scholar
Lewis, A. J. (1934a) Melancholia: a historical review. Journal of Mental Science, 80, 142.Google Scholar
Lewis, A. J. (1934b) Melancholia: a clinical survey of depressive states. Journal of Mental Science, 80, 277378.Google Scholar
Lewis, A. J. (1936) Melancholia: prognostic studies and case material. Journal of Mental Science, 82, 488558.Google Scholar
Lewis, A. J. (1938) States of depression: their clinical and aetiological differentiation. British Medical Journal, ii, 875878.CrossRefGoogle Scholar
Mapother, E. (1926) Discussion on manic-depressive psychosis. British Medical Journal, ii, 872879.Google Scholar
Mapother, E. & Lewis, A. J. (1937). Psychological medicine. In A Textbook of the Practice of Medicine (5th edn)(ed. Price, F. W.). London: Oxford University Press.Google Scholar
Quality Assurance Project (1983) A treatment outline for depressive disorders. Australian and New Zealand Journal of Psychiatry, 17, 129146.Google Scholar
Vaillant, G. E. & Schnurr, P. (1988) A forty-five year study of psychiatric impairment within a college sample selected for mental health. Archives of General Psychiatry, 45, 313319.Google Scholar
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