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The Leucocyte Antigenic System HL-A as a Possible Genetic Marker of Schizophrenia

Published online by Cambridge University Press:  29 January 2018

C. L. Cazzullo ,
E. Smeraldi  and
G. Penati
C. L. Cazzullo
Affiliation:
Institute of Clinical Psychiatry of the Milan Medical School, Via G. Besta 1, 20161 Milano/Affori, Italy
E. Smeraldi
Affiliation:
Institute of Clinical Psychiatry of the Milan Medical School, Via G. Besta 1, 20161 Milano/Affori, Italy
G. Penati
Affiliation:
Institute of Clinical Psychiatry of the Milan Medical School, Via G. Besta 1, 20161 Milano/Affori, Italy
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Extract

Many inheritance models of schizophrenia have been proposed, in view of its variable age at onset, variable familial occurrence and the relevant influence of a great number of environmental factors (Gottsman and Shields, 1967; Heston, 1970; Ödegård, 1972). However, the real genetic predisposition to schizophrenia has not yet been experimentally verified, and genetic markers have to be looked for, i.e. we need some character, genetically determined, whose transmission is associated with schizophrenia transmission: the more polymorphous the character, the greater will be the probability of finding such associations.

Type
Abstract
Information
The British Journal of Psychiatry , Volume 125 , Issue 584 , July 1974 , pp. 25 - 27
Copyright
Copyright © Royal College of Psychiatrists, 1974 

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