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II. the Incidence of Compliance Problems, Side-effects, Neurotic Symptoms and Depression

Published online by Cambridge University Press:  29 January 2018

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Summary

Seven years after the completion of the original trial, over 73% of patients were maintained on depot neuroleptics, and 70% had received such medication for over seven years. About 40% had presented with a problem of compliance at some time, and there was a significant correlation between poor compliance and in-patient admissions and schizophrenic relapses. The prevalence of parkinsonian side-effects, akathisia, and tardive dyskinesia was low. Non-psychotic symptoms were common, even in the absence of acute psychosis. Depression was found in a subgroup of patients; it was frequently reported as an indication for admission during follow-up period, and seemed to be part of the schizophrenic illness rather than a result of antipsychotic drug treatment.

Type
Long-term Depot Maintenance of Chronic Schizophrenic Out-patients: The Seven Year Follow-up of the Medical Research Council Fluphenazine/Placebo Trial
Information
The British Journal of Psychiatry , Volume 146 , Issue 5 , May 1985 , pp. 469 - 474
Copyright
Copyright © 1985 The Royal College of Psychiatrists 

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