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Hypertension, Multi-Infarct Dementia and Alzheimer's Disease

Published online by Cambridge University Press:  29 January 2018

D. St. Clair  and
L. J. Whalley
D. St. Clair
Affiliation:
MRC Brain Metabolism Unit
L. J. Whalley*
Affiliation:
MRC Brain Metabolism Unit Thomas Clouston Clinic, 153 Morningside Drive, Edinburgh
*
∗Correspondence.
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Summary

Retrospective review of 89 patients with pre-senile dementia followed by necropsy indicated significant differences between sub types of dementia. Patients with multi-infarct dementia (MID, 27 subjects) more often had cardiovascular abnormalities than patients with Alzheimer's disease (46 subjects). No patients with MID alone had a systolic blood pressure below 140 mm Hg, whereas 23 of 46 Alzheimer subjects and three of 16 patients with mixed features had such a systolic pressure.

Type
Research Article
Information
The British Journal of Psychiatry , Volume 143 , Issue 3 , September 1983 , pp. 274 - 276
Copyright
Copyright © 1983 The Royal College of Psychiatrists 

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References

Brody, M. J., Barron, K. W., Faber, J. E. et al (1982) Central nervous system control of blood pressure. In Hypertension (eds. Sleight, P. and Freis, E. D.). pp 199–215. London: Butterworths.Google Scholar
Corsellis, J. A. N. (1962) Mental Illness and the Ageing Brain. London: Oxford University Press.Google Scholar
Glen, A. I. M. & Christie, J. E. (1979) Early diagnosis of Alzheimer's disease: working definitions for clinical and laboratory criteria. In Alzheimer's Disease. Pp 122–28, (eds Glen, A. I. M. and Whalley, L. J.). Edinburgh: Churchill Livingstone.Google Scholar
Gustafson, L. & Nillson, L. (1982) Differential diagnosis of presenile dementia on clinical grounds. Acta Psychiatrica Scandinavica, 65, 194.CrossRefGoogle ScholarPubMed
Hackinski, V. C., Illiff, L. D., & Zilkha, E. (1975) Cerebral blood flow in dementia. Archives of Neurology, 32, 632–7.Google Scholar
Ladurner, G., Illiff, L. D. & Sanger, W. D. (1982) A clinical approach to vascular (multi-infarct) dementia. In The Ageing Brain (ed. Hoyer, S.). New York: Springer-Verlag.Google Scholar
Rosen, W. A., Terry, R. D. & Fuld, P. A. (1980) Pathological verification of ischaemic score in differentiation of dementias. Annals of Neurology, 7, (5), 486–8.CrossRefGoogle ScholarPubMed
Rossor, M. N. (1982) Neurotransmitters and CNS disease: Dementia. Lancet, 2, 1200–3.Google ScholarPubMed
Rothschild, D. (1941) The clinical differentiation of senile and arteriosclerotic psychosis. American Journal of Psychiatry, 32, 632–7.Google Scholar
Shephard, D. S. (1981) Reliability of blood pressure measurements: implications for designing and evaluating programmes to control hypertension. Journal of Chronic Diseases: 34, (5), 191–209.CrossRefGoogle Scholar
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