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HLA Antigens in Schizophrenia: A Family Study

Published online by Cambridge University Press:  29 January 2018

R. Chadda ,
P. Kulhara ,
T. Singh  and
S. Sehgal
R. Chadda
Affiliation:
Postgraduate Institute of Medical Education and Research, Chandigarh 160 012, India
P. Kulhara*
Affiliation:
Postgraduate Institute of Medical Education and Research, Chandigarh 160 012, India
T. Singh
Affiliation:
Postgraduate Institute of Medical Education and Research, Chandigarh 160 012, India
S. Sehgal
Affiliation:
Postgraduate Institute of Medical Education and Research, Chandigarh 160 012, India
*
∗ Correspondence
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Extract

HLA haplotypes A and B were studied in eight familes with two or more schizophrenic members. All index cases and all but two sick relatives satisfied Research Diagnostic Criteria for the diagnosis of schizophrenia; 45 subjects were studied. Data were analysed by sequential tests for the detection of linkage and by the affected sib-pair method. The results do not support a linkage between HLA and schizophrenia.

Type
Papers
Information
The British Journal of Psychiatry , Volume 149 , Issue 5 , November 1986 , pp. 612 - 615
Copyright
Copyright © 1986 The Royal College of Psychiatrists 

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