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Fluctuations of Free Choline Levels in Plasma of Alzheimer Patients Receiving Lecithin: Preliminary Observations

Published online by Cambridge University Press:  29 January 2018

Paz Chuaqui
Affiliation:
Institute of Psychiatry, De Crespigny Park, Denmark Hill, London SE5
Raymond Levy
Affiliation:
The Maudsley Hospital, Denmark Hill, London SE5

Summary

Plasmas of 12 patients currently taking part in a double-blind trial of lecithin in senile or presenile dementia of Alzheimer type were analysed for plasma choline levels at fixed intervals during lecithin treatment. The values were not maintained at a constant level and showed a decline after one or two months of treatment, often followed by a subsequent rise. Possible explanations for this observation are given, and its significance to the treatment of dementia discussed.

Type
Research Article
Copyright
Copyright © Royal College of Psychiatrists, 1982 

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