Hostname: page-component-cd9895bd7-gxg78 Total loading time: 0 Render date: 2024-12-25T07:23:19.528Z Has data issue: false hasContentIssue false

A Family with Alzheimer's Disease

Published online by Cambridge University Press:  02 January 2018

S. V. Patel*
Affiliation:
Monroe Community Hospital, University of Rochester, 435 East Henrietta Road, Rochester, New York 14603, USA;, St Mary's Hospital, Scarborough, Yorkshire

Abstract

A family with clinically diagnosed Alzheimer's disease in three siblings is described. The inheritance of Alzheimer's disease in this pedigree is consistent with autosomal dominant inheritance.

Type
Brief Report
Copyright
Copyright © Royal College of Psychiatrists, 1989 

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Breitner, J. C. S. & Folstein, M. F. (1984) Familial Alzheimer dementia: a prevalent disorder with specific clinical features. Psychological Medicine, 14, 6380.CrossRefGoogle ScholarPubMed
Cohen, D., Eisderfer, C. & Leverenz, J. (1982) Alzheimer's disease and maternal age. Journal of the American Geriatric Society, 30, 656659.Google Scholar
Constantinidis, J., Garrone, G. & Ajuriaguerra, J. (1962) L'heredite des demences de l'age avance. Encephale, 51, 301344.Google Scholar
Heston, L. L., Mastri, A. R., Anderson, E., et al (1981) Dementia of the Alzheimer type. Clinical genetics, natural history and associated conditions. Archives of General Psychiatry, 38, 10851090.Google Scholar
Heyman, A., Wilkinson, W. E., Hurwitz, B. J., et al (1983) Alzheimer's disease: genetic aspects and associated clinical disorders. Annals of Neurology, 14, 507515.Google Scholar
Isaacs, B. & Akhtar, A. J. (1972) The set test: a rapid test of mental function in old people. Age and Aging, 1, 222226.Google Scholar
Knesevich, J. W., LaBarge, E., Martin, R. L., et al (1982) Birth order and maternal age effect in dementia of the Alzheimer type. Psychiatry Research, 7, 345350.Google Scholar
McKhann, G., Drachman, D., Folstein, M., et al (1984) Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA work group under the auspices of the Department of Health and Human Services Task Force on Alzheimer's Disease. Neurology, 34, 939944.Google Scholar
Nee, L. E., Polinsky, R. J., Eldridge, R., et al (1983) A family with histologically confirmed Alzheimer's disease. Archives of Neurology, 40, 203208.Google Scholar
Pattie, A. H. & Gilleard, C. J. (1979) Manual of the Clifton Assessment Procedures for the Elderly (CAPE). Sevenoaks: Hodder & Stoughton.Google Scholar
Pearce, J. & Miller, E. (1973) Clinical Aspects of Dementia. London: Baillière Tindall.Google Scholar
Renvoize, E. B., Mindham, R. H. S., Stewart, M., et al (1986) Identical twins discordant for presenile dementia of Alzheimer type. British Journal of Psychiatry, 149, 509512.Google Scholar
Rossor, M. N., Iverson, L. L., Reynold, G. P., et al (1984) Neurochemical characteristics of early and late onset types of Alzheimer's disease. British Medical Journal, 228, 961964.Google Scholar
Sourander, P. & Sjogren, H. (1970) The concept of Alzheimer's disease and its clinical implications In Alzheimer's Disease, Ciba Foundation Symposium (eds G E. W. Wolstenholme & M. O'Connor). London: Churchill.Google Scholar
Sulkava, R., Rossi, L. & Knuutila, S. (1979) No elevated sister chromatid exchange in Alzheimer's disease. Acta Neurologica Scandinavica, 59, 156159.Google Scholar
Tagliavini, F. & Pilleri, G. (1983) Neuronal counts in basal nucleus of Meynert in Alzheimer's disease and in simple senile dementia. Lancet, i, 469470.Google Scholar
Terry, R. D. & Katzman, R. (1983) Senile dementia of the Alzheimer type. Annals of Neurology, 14, 497506.Google Scholar
Whalley, L. J., Carothers, A. D., Collyer, S., et al (1982) A study of familial factors in Alzheimer's disease. British Journal of Psychiatry, 140, 249256.Google Scholar
Submit a response

eLetters

No eLetters have been published for this article.