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Factors Associated with the Course and Outcome of Schizophrenia in India Results of a Two-Year Multicentre Follow-Up Study

Published online by Cambridge University Press:  02 January 2018

A. Verghese ,
J. K. John ,
S. Rajkumar ,
J. Richard ,
B. B. Sethi  and
J. K. Trivedi
A. Verghese*
Affiliation:
Department of Psychiatry, Christian Medical College, Vellore
J. K. John
Affiliation:
Department of Psychiatry, Christian Medical College, Vellore
S. Rajkumar
Affiliation:
Department of Psychiatry, Madras Medical College, Madras
J. Richard
Affiliation:
Department of Biostatistics, Christian Medical College, Vellore
B. B. Sethi
Affiliation:
Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow
J. K. Trivedi
Affiliation:
Department of Psychiatry, K. G. Medical College, Lucknow
*
∗Unit II, Department of Psychiatry, Christian Medical College, Vellore, India 632 002
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Abstract

The paper describes the two-year follow-up results from 323 out of 386 patients fulfilling a modified version of Feighner's criteria for diagnosis of schizophrenia, in Lucknow, Vellore, and Madras. There was remission in 66% of cases. Short duration of illness, consistent compliance with medication, positive attitudes of relatives and neighbours, absence of economic difficulties, increase in religious activities on the part of patients, a rural background, and a non-schizoid pre-morbid personality were associated with good outcome. Features of depression, dangerous behaviour, and absence of agitation were associated with poor outcome.

Type
Papers
Information
The British Journal of Psychiatry , Volume 154 , Issue 4 , April 1989 , pp. 499 - 503
Copyright
Copyright © Royal College of Psychiatrists, 1989 

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References

Brenner, M. H. (1973) Mental Illness and Economy. Cambridge, Massachusetts: Harvard University Press.Google Scholar
Brown, G., Birley, J. L. & Wing, J. K. (1972) Influence of family life on the course of schizophrenic disorder; a replication. British Journal of Psychiatry, 121, 241–258.CrossRefGoogle ScholarPubMed
Davis, J. M. (1975) Overview: maintenance therapy in psychiatry: 1, schizophrenia. American Journal of Psychiatry, 132, 1237–1245.Google Scholar
Dube, K. C. (1970) A study of prevalence and biosocial variables in mental illness in a rural and urban community in Uttar Pradesh, India. Acta Psychiatrica Scandinavica, 46, 327–332.CrossRefGoogle Scholar
Feighner, J. P., Robins, E., Guze, S. B., et al (1972) Diagnostic criteria for use in psychiatric research. Archives of General Psychiatry, 26, 57–63.CrossRefGoogle ScholarPubMed
Hogarty, G. E. & Goldberg, S. C. (1973) Drug and sociotherapy in aftercare of schizophrenia patients. Archives of General Psychiatry, 28, 54–64.CrossRefGoogle Scholar
Indian Council of Medical Research (1985) SOFACOS: 2 year follow up report. New Delhi: ICMR.Google Scholar
Leff, J. P. & Wing, J. K. (1971) Trial of maintenance therapy in schizophrenia. British Medical Journal, iii, 599–604.CrossRefGoogle Scholar
Lemkau, P., Tietze, C. & Cooper, M. (1942) Mental hygiene problems in an urban district. Mental Hygiene, 26, 100–119.Google Scholar
Lin, T. (1953) A study of the incidence of mental disorder in Chinese and other cultures. Psychiatry, 16, 313–336.CrossRefGoogle ScholarPubMed
Mayer-Gross, W., Slater, E. & Roth, M. (1969) Clinical Psychiatry. Baltimore: Williams and Wilkins.Google Scholar
Miles, C. P. (1977) Conditions predisposing to suicide: a review. Journal of Nervous and Mental Diseases, 164, 231–246.CrossRefGoogle ScholarPubMed
Murphy, H. B. M. & Raman, A. C. (1971) The chronicity of schizophrenia in indigenous tropical peoples. Results of a 12 year follow up study in Mauritius. British Journal of Psychiatry, 118, 489–497.CrossRefGoogle Scholar
Sartorius, N., Jablensky, A. & Shapiro, R. (1977) Two year follow up of the patients included in the WHO international pilot study of schizophrenia. Psychological Medicine, 7, 529–541.CrossRefGoogle Scholar
Sartorius, N., Jablensky, A., Korten, A., et al (1986) Early manifestations and first contact incidence of schizophrenia in different cultures. Psychological Medicine, 16, 909–928.CrossRefGoogle ScholarPubMed
Schofield, W., Hathaway, S. R., Hastings, D. W., et al (1954) Prognostic factors in schizophrenia. Journal of Consultation Psychology, 18, 155–166.CrossRefGoogle ScholarPubMed
Sethi, B. B., Gupta, S. C. & Rajkumar, (1967) Three hundred urban families – a psychiatric study. Indian Journal of Psychiatry, 9, 280–302.Google Scholar
Vaillant, G. E. (1962) The prediction of recovery in schizophrenia. Journal of Nervous and Mental Disease, 135, 534–543.CrossRefGoogle ScholarPubMed
Verghese, A., Beig, A., Senseman, L. A., et al (1973) A social and psychiatric study of a representative group of families in Vellore town. Indian Journal of Medical Research, 61, 608–620.Google ScholarPubMed
Verghese, A., Dube, K. C., John, J. K. et al (1985) Factors associated with the course and outcome of schizophrenia: Part I: Objectives and methodology. Indian Journal of Psychiatry, 27, 201–206.Google Scholar
World Health Organization (1979) Schizophrenia – an International Follow Up Study. New York: John Wiley.Google Scholar
Wing, J. K., Cooper, J. E. & Sartorius, N. (1974) The Measurement and Classification of Psychiatric Symptoms. London: Cambridge University Press.Google Scholar
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