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The Effect of Lithium Carbonate on the Electroencephalogram of Patients with Affective Disorders

Published online by Cambridge University Press:  29 January 2018

S. R. Platman
Affiliation:
Department of Psychiatry, Columbia University, and Associate Research Scientist, New York State Psychiatric Institute
R. R. Fieve
Affiliation:
Department of Psychiatry, Columbia University; Research Chief, New York State Psychiatric Institute

Extract

This paper examines the degree of electroencephalogram abnormality among the three phases of manic-depressive disease and the changes brought about by lithium carbonate. The earlier investigators (Berger, 1931; Lemere, 1936) reported no abnormalities in the EEGs of manic-depressive patients. Later workers (Davis, 1941; Hurst et al., 1954; Hes, 1960) found prominent changes between the two phases. However, Harding et al. (1966) noted no common pattern in their three cases when analysed for mean abundance, harmonic mean and variability of alpha rhythm.

Type
Research Article
Copyright
Copyright © Royal College of Psychiatrists, 1969 

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References

Andreani, G., Caselli, G. E., and Martelli, G. (1958). “Rilevi clinici ed eletrencefalografici durante il trattamento con sali di litio in malatti psichiatrici.” G. Psichiat. Neuropatol., 86, 273.Google Scholar
Berger, H. (1931). “Über das Electroenkephalogramm des Menschen, III.” Arch. Psychiatr. Nervenkr., 94, 19.CrossRefGoogle Scholar
Corcoran, A. C., Taylor, R. D. and Page, L. H. (1949). “Lithium poisoning from the use of salt substitute.” J.A.M.A., 139, 685.Google Scholar
Davis, P. A. (1941). “Electroencephalograms of manic-depressive patients.” Amer J. Psychiat., 98, 3.Google Scholar
Fieve, R. R., Platman, S. R., and Plutchik, R. (1968). “The use of lithium in affective disorders. Part 1: Acute endogenous depression. Part 2: Prophylaxis of depression in chronic recurrent affective disorders.” Amer J. Psychiat., 125, 487–99.Google Scholar
Harding, G., Jeavons, P. M., Jenner, F. A., Drummond, P., Sheridan, M., and Howells, G. G. (1966). “The electroencephalogram in three cases of periodic psychoses.” Electroenceph. clin. Neurophysiol., 21, 5966.Google Scholar
Hes, J. Ph. (1960). “Manic-depressive psychosis—a case report.” Electroenceph. clin. Neurophysiol., 12, 193–5.Google Scholar
Hill, D., and Parr, G. (1963). Electroencephalography, Macmillan Co., New York, 416.Google Scholar
Hurst, L. A., Mundy-Castle, A. C., and Beerstecher, D. M. (1954). “The electroencephalogram in manic-depressive psychosis.” J. ment. Sci., 100, 220–40.Google Scholar
Lemere, F. (1936). “The significance of individual differences in the Berger rhythm.” Brain, 59, 366.Google Scholar
Mayfield, D., and Brown, R. G. (1966). “The clinical laboratory and electroencephalographic effects of lithium.” J. psychiat. Res., 4, 207–19.Google Scholar
Platman, S. R., and Fieve, R. R. (1968a). “Biochemical aspects of lithium in the affective disorders.” Arch. gen. Psychiat., 19, 659–63.Google Scholar
Platman, S. R., and Fieve, R. R. (1968b). “Lithium retention and excretion: effects of sodium and fluid.” Arch. gen. Psychiat., 18, 591–4.Google Scholar
Platman, S. R., Rohrlich, J., and Fieve, R. R. (1968). “Absorption and excretion of lithium in manic-depressive disease.” Dis. nerv. Syst., 29, 733–8.Google Scholar
Schou, M. (1959). “Lithium in psychiatric therapy; stocktaking after 10 years.” Psychopharmacologia, 1, 65.Google Scholar
Wharton, R. N., and Fieve, R. R. (1966). “The use of lithium in the affective psychoses.” Amer. J. Psychiat., 123:6, 706–12.Google Scholar
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