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The Effect of Carbamazepine and Lithium on Remission from Affective Illness

Published online by Cambridge University Press:  02 January 2018

S. E. Watkins
Affiliation:
Department of Psychological Medicine, University of Wales College of Medicine
K. Callender
Affiliation:
Park Lane Hospital, Liverpool
D. R. Thomas
Affiliation:
Department of Psychological Medicine, University of Wales College of Medicine
S. F. Tidmarsh
Affiliation:
Department of Psychological Medicine, University of Wales College of Medicine
D. M. Shaw*
Affiliation:
Department of Psychological Medicine, University of Wales College of Medicine
*
Whitchurch Hospital, Cardiff, Wales

Abstract

Times in remission from affective illness were prolonged during treatment with lithium carbonate and carbamazepine, but lithium was the more effective. Similar global scores for the two drugs suggested that other factors may determine their acceptability.

Type
Research Article
Copyright
Copyright © 1987 The Royal College of Psychiatrists 

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References

Angst, J., Dittrich, A. & Grof, P. (1969) Course of endogenous affective psychosis and its modification by prophylactic administration of imipramine and lithium. International Pharmacopsychiatry, 2, 111.Google Scholar
Ballenger, J. C. & Post, R. M. (1980) Carbamazepine in manic-depressive illness. A new treatment. American Journal of Psychiatry, 137, 782790.Google ScholarPubMed
Blackburn, I. M., Loudon, J. B. & Ashworth, C. M. (1977) A new scale for measuring mania. Psychological Medicine, 7, 453458.CrossRefGoogle ScholarPubMed
Grof, P., Schou, M., Angst, J., Baastrup, P. & Weis, P. (1970) Methodological problems of prophylactic trials in recurrent affective disorders. British Journal of Psychiatry, 116, 599619.Google Scholar
Hamilton, M. (1967) Development of a rating scale for primary depressive illness. British Journal of Social and Clinical Psychiatry, 6, 278296.Google Scholar
Inanaga, K., Otsuki, S., Sarai, K., Takatashi, R., Hazama, H., Mori, A. & Watanabe, M. (1981) A preliminary double-blind study of the efficacy of carbamazepine in prophylaxis of manic depressive illness. Psychopharmacology, 73, 9596.Google Scholar
Kishimoto, A., Ogura, C., Hazama, H. & Inoue, K. (1983) Long term prophylactic effects of carbamazepine in affective disorders. British Journal of Psychiatry, 143, 327331.CrossRefGoogle Scholar
Montgomery, A. S. & Asberg, M. (1979) A new depression scale designed to be sensitive to change. British Journal of Psychiatry, 134, 382389.CrossRefGoogle ScholarPubMed
Nolen, W. A. (1983) Carbamazepine, a possible adjunct or alternative to lithium in bipolar disorder. Acta Psychiatrica Scandinavica, 67, 218225.Google Scholar
Okuma, T., Kishimoto, A., Inoue, K., Matsumoto, H., Ogura, A., Matsushita, T., Nakao, T. & Ogura, C. (1973) Antimanic and prophylactic effects of carbamazepine on manic depressive psychosis. Folia Psychiatrica and Neurologica Japonica, 27, 283297.Google Scholar
Takezabi, H. & Hanaoka, M. (1971) The use of carbamazepine in the control of manic depressive psychosis and other manic depressive states. Journal of Clinical Psychiatry, 13, 173182.Google Scholar
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