Hostname: page-component-cd9895bd7-8ctnn Total loading time: 0 Render date: 2024-12-24T04:32:01.196Z Has data issue: false hasContentIssue false

Depressive Disorder in Primary Care

Published online by Cambridge University Press:  02 January 2018

C. V. R. Blacker
Affiliation:
Department of Psychological Medicine, St Bartholomew's Hospital, London EC1A 7BE
A. W. Clare*
Affiliation:
Department of Psychological Medicine, St Bartholomew's Hospital, London EC1A 7BE
*
Correspondence

Abstract

Since the pioneering study of psychiatric morbidity in primary care by Shepherd et al in 1966, it has become increasingly apparent that a substantial proportion (between 20% and 25%) of patients consulting their GP are suffering from some form of psychiatric disturbance (Goldberg & Blackwell, 1970; Hoeper et al, 1979). The composition of this psychiatric morbidity has been shown to be almost wholly affective in nature and largely mild in degree. In their important review Jenkins & Shepherd (1983) recently summarised the now extensive findings relating to overall minor psychiatric morbidity in primary care. However, recent collaborative studies between psychiatrists and GPs have identified that within this dilute pool of minor disorders, lurks a significant but poorly served population of patients suffering from depressive disorders which are by no means minor in degree. A number of crucial issues regarding this depression in primary care emerge which the present paper aims to review. In particular, how common is it, and how severe? How does it present and what, if any, are its special characteristics? What is the precise relationship between depressive symptoms and depressive illness presenting to the GP and what is the relationship between physical illness and depression? And finally, what is the course and outcome of depression in this setting and what are the indications for and effect of treatment?

Type
Review Article
Copyright
Copyright © 1987 The Royal College of Psychiatrists 

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Barber, J. H. (1981) Depressive illness in general practice. In Acta Psychiatrica Scandinavica (suppl), 441446.CrossRefGoogle Scholar
Barraclough, B., Bunch, J., Nelson, B. & Sainsbury, P. (1974) A hundred cases of suicide: Clinical aspects. British Journal of Psychiatry, 125, 355373.CrossRefGoogle ScholarPubMed
Bebbinoton, P. E. (1978) The epidemiology of depressive disorders. In Culture, Medicine and Psychiatry; (ed. Kleinman, A. M.), 297341. Dordrecht, the Netherlands, D. Reidel Publishing Co. Google Scholar
Berndt, S. M., Berndt, D. J. & Byars, W. D. (1983) A multi-institutional study of depression in family practice. Journal of Family Practice, 16, 8387.Google ScholarPubMed
Brown, G. W. & Harris, T. (1978) Social Origins of Depression. London: Tavistock Publications.Google ScholarPubMed
Brown, , Craig, T. K. J. & Harris, T. O. (1985) Depression: disease or distress? Some epidemiological considerations. British Journal of Psychiatry, 147, 612622.CrossRefGoogle ScholarPubMed
Burns, B. J., Orso, C. & Jacobsen, H. (1977) Utilisation of health and mental health out-patient services in organised medical care settings. In Final report, National Institute for Mental Health, Contract No. 278-76-0027.Google Scholar
Casey, P. R., Dillon, S. & Tyrer, P. J. (1984) The diagnostic status of patients with conspicuous psychiatric morbidity in primary care. Psychological Medicine, 14, 673683.CrossRefGoogle ScholarPubMed
Chancellor, A., Mant, A. & Andrews, G. (1977) The general practitioner's identification and management of emotional disorders. Australian Family Physician, 6, Research report.Google ScholarPubMed
Clare, A. W. (1982) Problems of psychiatric classification in general practice. In Psychiatry and General Practice, (eds Clare, A. W. & Lader, M.). London: Academic Press.Google Scholar
Clare, A. W. Williams, P. (1981) Factors leading to psychotropic drug treatment. In The Misuse of Psychotropic Drugs. London: Gaskell Books.Google Scholar
Cooper, B. (1972) Clinical and social aspects of chronic neurosis. In Psychosocial Disorders in General Practice, (eds Williams, P. & Clare, A. W.). London: Academic Press.Google Scholar
Cooper, B. & Fry, J. (1969) A longitudinal study of psychiatric morbidity in a General Practice population. British Journal of Social Medicine, 23, 210217.Google Scholar
Corney, R. H. (1984) The effectiveness of attached social workers in the management of depressed female patients in general practice. In Psychological Medicine (suppl), 6.CrossRefGoogle Scholar
Craig, T. J. & Van Natta, P. (1976) Presence and persistence of depressive symptoms in patient and community populations. American Journal of Psychiatry, 133, 14261429.Google ScholarPubMed
Craig, , & Van Natta, P. (1979) Influence of demographic characteristics on two measures of depressive symptoms. Archives of General Psychiatry, 36, 149154.CrossRefGoogle ScholarPubMed
Crombie, D. L. (1974) Changes in patterns of recorded morbidity. In Benefits and Risks of Medical Care, (ed. Taylor, D.). London: Office of Health Economics.Google Scholar
Davies, B. & Blakshi, T. (1973) Course of depression: a comparison of depression in general practice and hospital. In Classification and Prediction of Outcome of Depression. Stuttgart: F. K. Schattauer.Google Scholar
Downing, R. W. & Rickels, K. (1974) Mixed anxiety and depression: fact or myth? Archives of General Psychiatry, 30, 312317.CrossRefGoogle ScholarPubMed
Dunn, G. (1985) Records or psychiatric morbidity in general practice: the National Morbidity Surveys. Psychological Medicine, 15, 223226.CrossRefGoogle ScholarPubMed
Dunn, G. & Skuse, D. (1981) The natural history of Depression in General Practice: stochastic models. Psychological Medicine, 11, 755764.CrossRefGoogle ScholarPubMed
Eastwood, M. R. & Trevelyan, M. H. (1972) The relationship between physical and psychiatric disorder. Psychological Medicine, 2, 363372.CrossRefGoogle ScholarPubMed
Endicott, J. & Spitzer, R. L. (1979) The use of the Research Diagnostic Criteria and the Schedule for Affective Disorders and Schizophrenia to study Affective disorders. American Journal of Psychiatry, 136, 5256.Google ScholarPubMed
Endicott, J. & Spitzer, R. L. Fleiss, J. L. & Cohen, J. (1976) The Global Assessment Scale. Archives of General Psychiatry, 33, 766771.CrossRefGoogle ScholarPubMed
Fahy, T. J. (1974) Depression in Hospital and in General Practice: a direct clinical comparison. British Journal of Psychiatry, 124, 240242.CrossRefGoogle ScholarPubMed
Freeling, P., Rao, B. M., Paykel, E. S., Sirelino, L. I. & Burton, R. H. (1985) Unrecognised depression in general practice. British Medical Journal, 290, 18801883.CrossRefGoogle ScholarPubMed
Gastpar, M., Gilsdorf, U. & Gastpar, G. (1981) Diagnosis of Depression in General Practice. In Prevention and Treatment of Depression, (eds Ban, T. A., Gonzalez, R., Jablensky, A. S., Sartorius, N. A. & Vartanian, F. E.). Baltimore: University Park Press.Google Scholar
Goldberg, D. & Blackwell, B. (1970) Psychiatric illness in general practice: a detailed study using a new method of case identification. British Medical Journal, 2, 439443.CrossRefGoogle Scholar
Goldberg, D. & Huxley, P. (1980) Mental Illness in the Community. London: Tavistock Press.Google Scholar
Goldberg, D. Rickels, K., Downing, R. & Hesbacher, P. (1976) A comparison of two psychiatric screening tests. British Journal of Psychiatry, 129, 6167.CrossRefGoogle ScholarPubMed
Goldberg, D., Steele, J., Smith, C. & Spivey, L. (1980) Training family practice residents to recognise psychiatric disturbances. Final report, Contract No. ADAMHA 278-78-003(DB). South Carolina: Department of Biometrics and Family Practice. Medical University of South Carolina.Google Scholar
Hankin, J. & Locke, B. (1983) Extent of depressive symptomatology among patients seeking care in a prepaid group practice. Psychological Medicine, 13, 10001007.CrossRefGoogle Scholar
Henderson, S. (1981) Social relationships, adversity, and neurosis: an analysis of prospective observations. British Journal of Psychiatry, 138, 391398.CrossRefGoogle ScholarPubMed
Henderson, , Duncan-Jones, P., McAuley, H. & Ritchie, K. (1978) The patient's primary group. British Journal of Psychiatry, 132, 7486.CrossRefGoogle Scholar
Hesbacher, P. T., Rickels, K. & Goldberg, D. (1975) Social factors and neurotic symptoms in family practice. American Journal of Public Health, 65, 148155.CrossRefGoogle ScholarPubMed
Hoeper, E. W., Nycz, G. R., Cleary, P. D., Regier, D. A. & Goldberg, I. D. (1979) Estimated prevalence of RDC mental disorder in Primary Medical Care. International Journal of Mental Health, 8, 615.CrossRefGoogle Scholar
Hoeper, E. W., Nycz, G. R., Regier, D. A. (1980) Diagnosis of mental disorder in adults and increased use of health services in four out-patient settings. American Journal of Psychiatry, 137, 207210.Google Scholar
Hoeper, E. W., Nycz, G. R., Kessler, L. G., Burke, J. D. & Pierce, W. (1984) The usefulness of screening for mental illness. Lancet, i, 3335.CrossRefGoogle Scholar
Horwitz, A. (1977) The pathways into psychiatric treatment: some differences between men and women. Journal of Health and Social Behaviour, 18, 169178.CrossRefGoogle ScholarPubMed
Houpt, J., Orleans, C. & George, L. K. (1979) The Importance of Mental Health Services in General Health Care. Massachusetts: Cambridge.Google Scholar
Hurry, J., Tennent, C. & Bebbington, P. (1980) Selective factors leading to psychiatric referral. In Acta Psychiatrica Scandinavica, (suppl.) 285, 315323.CrossRefGoogle Scholar
Ingham, J. G. & Miller, P. M. (1979) Symptom prevalence and severity in a general practice population. Journal of Epidemiology and Community Health, 33, 191198.CrossRefGoogle Scholar
Jenkins, R. & Shepherd, M. (1983) Mental illness and general practice. In Mental Illness: Changes and Trends, (ed. Bean, P.). Chichester: Wiley.Google Scholar
Johnson, D. A. W. (1973) Treatment of depression in general practice. British Medical Journal, 2, 1820.CrossRefGoogle ScholarPubMed
Johnson, D. A.W. (1974) A study of the use of antidepressant medication in general practice. British Journal of Psychiatry, 125, 186192.CrossRefGoogle ScholarPubMed
Johnson, D. A.W. (1981) Depression: treatment compliance in general practice. In Acta Psychiatrica Scandinavica, (suppl.) 63, 447453.CrossRefGoogle Scholar
Johnson, D. Goldberg, D. (1976) Psychiatric screening in General Practice: a controlled trial. Lancet, i, 605608.CrossRefGoogle Scholar
Johnson, D. & Mellor, V. (1977) The severity of depression in patients treated in general practice. Journal of the Royal College of General Practitioners, 27, 419422.Google ScholarPubMed
Kedward, H. B. & Cooper, B. (1969) Neurotic disorders in urban practice: a three-year follow-up. Journal of the College of General Practitioners, 12, 148163.Google Scholar
Lader, M. (1975) The social implications of psychotropic drugs. Royal Society of Health Journal, 95 (b), 304305.CrossRefGoogle ScholarPubMed
Locke, B. Z., Krantz, G. & Kramer, M. (1966) Psychiatric need and demand in a prepaid group practice programme. American Journal of Public Health, 56, 895904.CrossRefGoogle Scholar
Mann, A. H., Jenkins, R. & Belsey, E. (1981) The twelve-month outcome of patients with neurotic illness in general practice. Psychological Medicine, 11, 535550.CrossRefGoogle ScholarPubMed
Marks, J. N., Goldberg, D. & Hillier, V. F. (1979) Determinants of the ability of general practitioners to detect psychiatric illness. Psychological Medicine, 9, 337353.CrossRefGoogle ScholarPubMed
Mazer, M. (1967) Psychiatric disorders in General Practice: the experience of an Island community. American Journal of Psychiatry, 124, 609615.CrossRefGoogle ScholarPubMed
Mitchell, A. R. K. (1985) Psychiatrists in Primary Health Care Settings. British Journal of Psychiatry, 147, 371379.CrossRefGoogle ScholarPubMed
Myers, J. K., Weissman, M. M., Tischler, G. L., Holzer, C.E. et al (1984) Six-month prevalence of psychiatric disorders in three communities. Archives of General Psychiatry, 41, 959967.CrossRefGoogle ScholarPubMed
Nielsen, A. C. & Williams, T. A. (1980) Depression in ambulatory medical patients. Archives of General Psychiatry, 37, 9991004.CrossRefGoogle Scholar
Paykel, E. S. (1974) Recent life events and clinical depression. In Life Stress and Illness (eds Gunderson, E. K. et al. Springfield, Illinois, C. C. Thomas Google Scholar
Paykel, E. S., Klerman, G. L. & Prusoff, B. A. (1974) Prognosis of depression and the endogenous-neurotic distinction. Psychological Medicine, 4, 5764.CrossRefGoogle ScholarPubMed
Illinois, , Rao, B. M. & Taylor, C. N. (1984) Life stress and symptom pattern in out-patient depression. Psychological Medicine, 14, 559568.Google Scholar
Porter, A. M. W. (1970) Depressive illness in a general practice: A demographic study and a controlled trial of Imipramine. British Medical Journal, 1, 770778.CrossRefGoogle Scholar
Raft, D., Davidson, J., Toomey, T. C, Spencer, R. & Lewis, B. (1975) In-patient and out-patient patterns of psychotropic drug prescribing in non-psychiatrist physicians. American Journal of Psychiatry, 132, 13091312.Google Scholar
Regier, D. A., Burke, J. D., Manderscheid, R. W. & Burns, B. J. (1985) The chronically mentally ill in primary care. Psychological Medicine, 15, 265273.CrossRefGoogle ScholarPubMed
Roberts, R. & Vernon, S. (1982) Depression in the community. Archives of General Psychiatry, 39, 14071409.CrossRefGoogle ScholarPubMed
Robins, E. & Guze, S. (1972) Classification of affective disorders: the primary-secondary, the endogenous, and the neurotic – psychotic concepts. In Recent Advances in the Psychobiology of the Depressive Illnesses. Published by the Department of Health, Education, and Welfare. (HSM) 70-9053.Google Scholar
Robins, L. N., Helzer, J. E., Weissman, M. M., Orvaschel, H. et al (1984) Lifetime Prevalence of specific psychiatric disorders in three sites. Archives of General Psychiatry, 41, 949958.CrossRefGoogle ScholarPubMed
Salkind, M. R. (1969) Beck Depression Inventory in General Practice. Journal of the Royal College of General Practitioners, 18, 267.Google ScholarPubMed
Shepherd, M., Cooper, M., Brown, A. C. & Kalton, G. (1966; 2nd ed. 1981). Psychiatric Illness in General Practice. Oxford/New York: Oxford University Press.Google Scholar
Sireling, L. I., Paykel, E. St. Freeling, P., Rao, B. M. & Patel, S. P. (1985a) Depression in general practice: case thresholds and diagnosis. British Journal of Psychiatry, 147, 113118.CrossRefGoogle ScholarPubMed
Sireling, L. I., Paykel, E. St. Freeling, P., Rao, B. M. & Patel, S. P. (1985b) Depression in general practice: clinical features and comparison with out-patients. British Journal of Psychiatry, 147, 119126.CrossRefGoogle ScholarPubMed
Sowerby, P. (1977) Balint re-assessed. Journal of the Royal College of General Practitioners, 27, 583589.Google Scholar
Spitzer, R. L., Endicott, J. & Robins, E. (1978) Research Diagnostic Criteria: rationale and reliability. Archives of General Psychiatry, 35, 773782.CrossRefGoogle ScholarPubMed
Teasdale, J. D., Fenell, M. J. V., Hibbert, G. A. & Amies, P. L. (1984) Cognitive therapy for major depressive disorder in primary care. British Journal of Psychiatry, 144, 400406.CrossRefGoogle ScholarPubMed
Thompson, J., Rankin, H., Ashcroft, C. W., Yates, C. M. et al (1982) The treatment of depression in general practice. Psychological Medicine, 12, 741751.CrossRefGoogle Scholar
Tischler, G. L., Henisz, J. E., Myers, J. K. & Boswell, P. C. (1975a) Utilization of mental health services. Patienthood and the prevalence of symptomatology in the community. Archives of General Psychiatry, 32, 411415.CrossRefGoogle ScholarPubMed
Tischler, G. L., Heinisz, J. E., Myers, J. K. & Boswell, P. C. (1975b) Utilization of mental health services II. Mediators of service allocation. Archives of General Psychiatry, 32, 416418.CrossRefGoogle ScholarPubMed
Tyrer, P. (1978) Drug-treatment of psychiatric patients in General Practice. British Medical Journal, ii, 1008.CrossRefGoogle Scholar
Watts, C. A. H. (1947) Endogenous depression in general practice. British Medical Journal, 1, 11.CrossRefGoogle ScholarPubMed
Watts, C. A. H. (1966) Depressive Disorders in the Community. Bristol: John Wright.Google Scholar
Watts, C. A. H. (1970) A long term follow-up of mental hospital admissions from a rural community. Journal of the Royal College of General Practitioners, 20, 79.Google ScholarPubMed
Watts, C. Conte, E. C. & Kuensberg, E. V. (1964) Survey of mental illness in General Practice. British Medical Journal, 2, 13511359.CrossRefGoogle ScholarPubMed
Weissman, M. & Klerman, G. L. (1977) The Chronic Depressive in the community: unrecognized and poorly treated. In Comprehensive Psychiatry, 18, 523532.CrossRefGoogle ScholarPubMed
Watts, C. & Myers, J. K. (1978) Rates and risks of depressive symptoms in a US urban community. Acta Psychiatrica Scandinavica, 57, 219231.Google Scholar
Watts, C. & Thompson, W. D. (1981) Depression and its treatment in a US urban community. Archives of General Psychiatry, 38, 417421.Google Scholar
Widmer, R. B. & Cadoret, R. J. (1978) Depression in primary care: changes in pattern of patient visits and complaints during a development depression. Journal of Family Practice, 7, 293302.Google ScholarPubMed
Wing, J. K. (1976) A technique for studying psychiatric morbidity in in-patient and out-patient series and a general population sample. Psychological Medicine, 6, 665671.CrossRefGoogle Scholar
Widmer, R. B., Cooper, J. E. & Sartorjus, N. (1974) The Measurement and Classification of Psychiatric Symptoms. Cambridge: Cambridge University Press.Google Scholar
Mann, S. A., Leff, J. P. et al (1978) The concept of a ‘case’ in psychiatric population surveys. Psychological Medicine, 8, 203217.Google Scholar
Widmer, R. B., Bebbington, P. E., Hurry, J. & Tennant, C. (1981) The prevalence of the general population of disorders familiar to psychiatrists in hospital practice. In What is a Case? The Problem of Definition in Psychiatric Community Surveys, (eds Wing, J. K., Bebbington, P. E. & Robins, L. N.). London: Grant Mclntyre.Google Scholar
Wing, L., Wing, J. K. & Hailey, A. (1967) The use of psychiatric services in three urban areas: An international case register study. Social Psychiatry, 2, 158167.CrossRefGoogle Scholar
Winokur, G., Tsuang, M. & Crose, R. (1971) The Iowa 500: affective disorder in the relatives of manic and depressed patients. American Journal of Psychiatry, 139, 209212.Google Scholar
Wright, J. H., Bell, R. A., Kuhn, C. C, Rush, E. A., Patel, N. & Redmon, J. E. (1980) Depression in Family Practice patients. Southern Medical Journal, 73, 10311034.CrossRefGoogle ScholarPubMed
Zung, W. W. K., Magill, M., Moore, J. & George, D. T. (1983) Recognition and Treatment of Depression in a Family Medicine Practice. Journal of Clinical Psychiatry, 44, 1.Google Scholar
Submit a response

eLetters

No eLetters have been published for this article.