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Depression Spectrum Disease versus Pure Depressive Disease: Some Further Data

Published online by Cambridge University Press:  29 January 2018

George Winokur ,
Remi Cadoret ,
M. Baker  and
J. Dorzab
George Winokur
Affiliation:
Department of Psychiatry, University of Iowa College of Medicine, Iowa City, Iowa 52242, U.S.A.
Remi Cadoret
Affiliation:
Department of Psychiatry, University of Iowa College of Medicine, Iowa City, Iowa 52242, U.S.A.
M. Baker
Affiliation:
Psychiatry, Fort Smith, Arkansas, U.S.A.
J. Dorzab
Affiliation:
Psychiatry, 918 Lexington Avenue, Fort Smith, Arkansas, U.S.A.
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Extract

In a recent letter to this Journal, Galdi (1974) stated, ‘Through what is … a genetic approach to classification, Winokur and associates … reported the isolation of two subtypes of unipolar depressive disorder differentiated by age of onset and contrasting family history pattern.’ These subtypes (Winokur, 1974) are termed depression spectrum disease (early-onset; most likely female; familial alcoholism and/or antisocial personality) and pure depressive disease (late onset; equally male or female; little familial alcoholism and/or antisocial personality).

Type
Research Article
Information
The British Journal of Psychiatry , Volume 127 , Issue 1 , July 1975 , pp. 75 - 77
Copyright
Copyright © Royal College of Psychiatrists, 1975 

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References

Baker, M., Dorzab, J., Winokur, G. & Cadoret, R. (1971) Depressive disease: classification and clinical characteristics. Comprehensive Psychiatry, 12, 354–65.CrossRefGoogle ScholarPubMed
Galdi, J. (1974) Typologies of depressive disorder based on family history or genetic data. British Journal of Psychiatr. (Correspondence), 124, 615–16.CrossRefGoogle Scholar
Stenstedt, A. (1952) A study in manic depressive psychosis. Acta Psychiatria et Neurologia Scandinavica, Suppl. 79, 1–111.Google Scholar
Winokur, G. (1974) The division of depressive illness into depression spectrum disease and pure depressive disease. International Pharmacopsychiatry, 9, 5–13.Google Scholar
Winokur, G., Cadoret, R., Dorzab, J. & Baker, M. (1971) Depressive disease, a genetic study. Archives of General Psychiatry, 24, 135–44.CrossRefGoogle ScholarPubMed
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