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Comparison of the Prophylactic Action of Flupenthixol with Placebo in Lithium Treated Manic-Depressive Patients

Published online by Cambridge University Press:  29 January 2018

J. Esparon
Affiliation:
Murray Royal Hospital, Perth
J. Kolloori
Affiliation:
Royal Dundee Liff Hospital
G. J. Naylor*
Affiliation:
Royal Dundee Liff Hospital, Dundee DD2 51F
A. M. McHarg
Affiliation:
Royal Dundee Liff Hospital
A. H. W. Smith
Affiliation:
Royal Dundee Liff Hospital
S. E. Hopwood
Affiliation:
Royal Dundee Liff Hospital
*
Correspondence

Abstract

A double-blind cross-over trial of depot flupenthixol in recurrent manic depressive psychosis was carried out. Ail patients continued on lithium. Eleven patients completed the two-year trial. Flupenthixol appeared to have no prophylactic effect.

Type
Brief Reports
Copyright
Copyright © 1986 The Royal College of Psychiatrists 

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References

Ahlpors, U. G., Baastrup, P. C., Dencker, S. J., Elgen, K., Lingjafrde, O., Pedersen, V., Schou, M. & Aaskoven, O. (1981) Flupenthixol decanoate in recurrent manic depressive illness. A comparison with lithium. Acta Psychiatrica Scandinavica, 64, 226237.Google Scholar
Coppen, A., Montgomery, S. A., Gupta, R. K. & Bailey, J. E. (1976) A double blind comparison of lithium carbonate and Maprotiline in the prophylaxis of the affective disorders. British Journal of Psychiatry, 128, 479485.Google Scholar
Coppen, A., Abou-Saleh, M., Milln, P., Bailey, J. & Wood, K. (1984) Decreasing lithium dosage reduces morbidity and side effects during prophylaxis. Journal of Affective Disorders, 6, 353362.Google Scholar
Naylor, G. & Scott, C. (1980) Depot injections for affective disorders. British Journal of Psychiatry, 136, 105.Google Scholar
Reiter, P. (1969) On flupenthixol, an antidepressant of a new chemical group. British Journal of Psychiatry, 115, 13991402.Google Scholar
Sonne, L. M. (1966) Behandling af depressive tilstande med flupenthixol. Nordisk Psychiatrisk Tiddskrift. 20, 322324.Google Scholar
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