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Changes in Cognition with Pharmacotherapy and Cognitive Therapy

Published online by Cambridge University Press:  29 January 2018

I. M. Blackburn*
Affiliation:
M.R.C. Brain Metabolism Unit, Royal Edinburgh Hospital, Thomas Clouston Clinic, 153 Morningside Drive, Edinburgh, EH10 5LG
*
Correspondence.

Summary

A treatment trial comparing cognitive therapy and pharmacotherapy, alone and in combination, in depressed out-patients, indicated that outcome on cognitive variables was similar to outcome on mood and severity measures, pharmacotherapy being less effective than cognitive therapy or the combined treatment in a hospital and a general practice sample. While combined treatment was superior to cognitive therapy in the hospital outpatients, the two treatments were equivalent in the general practice. Significant effects were obtained on measures of views of self, the world and the future, whose validity was demonstrated. The pattern of change through treatment showed the same order of progress for responders, while non-responders to cognitive therapy tended to do worst. The specificity of treatment effect is discussed.

Type
Research Article
Copyright
Copyright © 1983 The Royal College of Psychiatrists 

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Footnotes

Butler Hospital, Providence, Rhode Island, U.S.A.

References

Bech, P., Gram, L. F., Dein, E., Jacobsen, O., Vitger, J. & Bolwig, T. G. (1975) Quantitative rating of depressive states. Acta Psychiatrica Scandinavica, 51, 161–70.Google Scholar
Beck, A. T. (1967) Depression: Clinical, Experimental and Theoretical Aspects. London: Staples Press.Google Scholar
Beck, A. T. & Beaumesderfer, A. (1974) Assessment of depression: The Depression Inventory. In Modern Problems in Pharmacopsychiatry. Vol. 7. Psychological Measurements in Psychopharmacology, (ed. Pichot, P.). Basel: S. Karger.Google Scholar
Beck, A. T., Weissman, A., Lester, D. & Trexler, L. (1974) The measurement of pessimism: The Hopelessness Scale. Journal of Consulting and Clinical Psychology, 42, 851–65.Google Scholar
Beck, A. T., Kovacs, M. & Weissman, A. (1975) Hopeless and suicidal behaviour. An overview. Journal of the American Medical Association, 234, 1146–9.Google ScholarPubMed
Beck, A. T., Rush, A. J., Shaw, B. F. & Emery, G. (1979) Cognitive therapy of Depression: a Treatment Manual. New York: Guilford.Google Scholar
Blackburn, I. M. & Bishop, S. (1981) Is there an alternative to drugs in the treatment of depressed ambulatory patients? Behavioural Psychotherapy, 9, 96104.Google Scholar
Blackburn, I. M., Bishop, S., Glen, A. I. M., Whalley, L. J. & Christie, J. E. (1981) The efficacy of cognitive therapy in depression: a treatment trial using cognitive therapy and pharmacotherapy, each alone and in combination. British Journal of Psychiatry, 139, 181–9.Google Scholar
Di Mascio, A., Weissmann, M. M., Prufoff, B. A., Neu, C., Zwilling, M. & Klerman, G. L. (1979) Differential symptoms reduction by drugs and psychotherapy in acute depression. Archives of General Psychiatry, 36, 1450–6.Google ScholarPubMed
Friedman, A. (1975) Interaction of drug therapy with marital therapy in depressed patients. Archives of General Psychiatry, 32, 619–37.Google Scholar
Fuchs, C. Z. & Rehm, L. P. A. (1977) A self-control behaviour therapy programme for depression. Journal of Consulting and Clinical Psychology, 45, 205–15.Google Scholar
Greene, S. M. (1981) Levels of measured hopelessness in the general population. British Journal of Clinical Psychology, 20, 1114.Google Scholar
Kelly, G. A. (1955) The Psychology of Personal Constructs. New York: Norton.Google Scholar
Lewinsohn, P. M., Sullivan, J. M. & Grosscup, S. (1980) Changing reinforcements: An approach to the treatment of depression. Psychotherapy: Theory, Research and Practice, 17, 322–33.CrossRefGoogle Scholar
McLean, P. (1982) Behavioural therapy: Theory and research. In Short-term Psychotherapies for Depression. (ed. Rush, A. J.). Chichester: John Wiley.Google Scholar
McLean, P. & Hakstian, A. R. (1979) Clinical depression: comparative efficacy of out-patient treatment. Journal of Consulting and Clinical Psychology, 47, 815–36.CrossRefGoogle Scholar
Minkoff, K., Bergman, E. & Beck, R. (1973) Hopelessness, depression and attempted suicide. American Journal of Psychiatry, 130, 455–9.CrossRefGoogle ScholarPubMed
Nekanda-Trepka, C. J. S., Bishop, S. & Blackburn, I. M. (1983) Hopelessness and Depression. British Journal of Clinical Psychology, 22, 4960.Google Scholar
Osgood, C. E., Sua, G. J. & Tannenbaum, P. G. (1957) The measurement of meaning. Urbana: University of Illinois.Google Scholar
Rounsaville, B. J., Klerman, G. J. & Weissmann, M. M. (1981) Do psychotherapy and pharmacotherapy for depression, conflict? Archives of General Psychiatry, 35, 24–9.Google Scholar
Rush, A. J., Beck, A. T., Kovacs, M. & Hollon, S. D. (1977) Comparative efficacy of cognitive therapy and pharmacotherapy in the treatment of depressed outpatients. Cognitive Therapy and Research, 1, 1737.CrossRefGoogle Scholar
Rush, A. J., Kovacs, M., Beck, A. T., Weissenburger, & Hollon, S. D. (1981) Differential effects of cognitive therapy and pharmacotherapy on depressive symptoms. Journal of Affective Disorder, 3, 221–9.Google Scholar
Schwab, J. J., Bialow, M. R. & Holzer, C. E. (1967) A comparison of two rating scales for depression. Journal of Clinical Psychology, 23, 94–6.Google Scholar
Shaw, B. F. (1977) A comparison of cognitive therapy and behaviour therapy in the treatment of depression. Journal of Consulting and Clinical Psychology, 45, 549–51.CrossRefGoogle ScholarPubMed
Snaith, R. P., Constantopoulos, A. A., Jardine, M. Y. & McGuffin, P. (1978) A clinical scale for self-assessment of irritability. British Journal of Psychiatry, 132, 164–71.Google Scholar
Taylor, F. G. & Marshall, W. L. (1977) Experimental analyses of a cognitive behavioural therapy for depression. Cognitive Therapy and Research, 1, 5972.Google Scholar
Zeiss, A. M., Lewinsohn, P. M. & Munoz, R. F. (1979) Non-specific improvement effects in depression using interpersonal cognitive and pleasant events focussed treatment. Journal of Consulting and Clinical Psychology, 47, 427–39.Google Scholar
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