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Bromazepam, Medazepam, Chlordiazepoxide in treatment of Neurotic Anxiety

Published online by Cambridge University Press:  29 January 2018

R. J. Kerry ,
C. M. McDermott  and
J. E. Orme
R. J. Kerry
Affiliation:
The Northern General Hospital, Sheffield S5 7AU
C. M. McDermott
Affiliation:
The Northern General Hospital, Sheffield S5 7AU
J. E. Orme
Affiliation:
The Northern General Hospital, Sheffield S5 7AU
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Extract

A new benzodiazepine, bromazepam, 6 mg. three times a day was compared in a double-blind trial with medazepam, 10 mg. three times a day and with chlordiazepoxide, 10 mg. three times a day. Each drug was given for two weeks. The first 50 cases attending the out-patient department were selected. All were suffering from neurotic anxiety and were comparable to those patients for whom sedation is commonly and properly prescribed in general practice. There was no selection for either age or sex.

Type
Abstract
Information
The British Journal of Psychiatry , Volume 124 , Issue 582 , May 1974 , pp. 485 - 486
Copyright
Copyright © Royal College of Psychiatrists, 1974 

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References

Jenner, F. A., Kerry, R. J., and Parkin, D. (1961). ‘A controlled comparison of methaminodiazepoxide (chlordiazepoxide—Librium) and amylobarbitone in the treatment of anxiety in neurotic patients.’ Journal of Mental Science. 107, 583–9.Google Scholar
Jenner, F. A., Kerry, R. J. (1967). ‘Comparison of diazepam, chlordiazepoxide and amylobarbitone (a multidose double-blind crossover study).’ Diseases of the Nervous System, 28, 245–9.Google Scholar
Kerry, R. J., and Jenner, F. A. (1962). ‘A double-blind crossover comparison of diazepam (Valium, RO 5-2807) with chlordiazepoxide (Librium) in the treatment of neurotic anxiety.’ Psychopharmacologia, 3, 302–6.Google Scholar
Kerry, R. J., Jenner, F. A., and Pearson, I. B. (1972). ‘A double-blind crossover comparison of RO 5-3350, bromazepam, diazepam (Valium) and chlordiazepoxide (Librium) in the treatment of neurotic anxiety.’ Psychosomatics, 13, 122–4.Google Scholar
Kerry, R. J., and McDermott, C. M. (1971). ‘Medazepam compared with amylobarbitone in treatment of anxiety.’ British Medical Journal, i, 151–2.Google Scholar
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