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Bereitschaftpotential in schizophrenia

Published online by Cambridge University Press:  03 January 2018

Taha Karaman*
Affiliation:
Akdeniz University Medical Faculty, Antalya, Turkey
Sibel Özkaynak
Affiliation:
Akdeniz University Medical Faculty, Antalya, Turkey
Korkut Yaltkaya
Affiliation:
Akdeniz University Medical Faculty, Antalya, Turkey
Çetin Büyükberker
Affiliation:
Akdeniz University Medical Faculty, Antalya, Turkey
*
Professor T. Karaman, Department of Psychiatry, Akdeniz University Medical Faculty, 07070 Antalya, Turkey, Fax: 90 242 2274490

Abstract

Background

Several reports have documented the presence of motor abnormalities in schizophrenic patients.

Method

Thirty schizophrenics and 28 healthy controls were included in the study. Scalp-recorded bereitschaftpotentials (BPs) generated prior to voluntary movements were recorded in all subjects.

Results

The early (NSI) and late components of BP and peak negativity were reduced in all schizophrenic patients. In particular, the NSI was reduced in patients with positive symptoms, and the late component in patients with negative symptoms.

Conclusions

These findings provide further support for the involvement of frontal cortex, subcortical structures and their connections in schizophrenia, and highlight some differences between positive and negative symptom clusters.

Type
Papers
Copyright
Copyright © 1997 The Royal College of Psychiatrists 

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