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Adrenocortical Suppression Presenting with Agitated Depression, Morbid Jealousy, and a Dementia-Like State

Published online by Cambridge University Press:  02 January 2018

F. Hassanyeh*
Affiliation:
Department of Psychiatry, Royal Victoria Infirmary, Newcastle upon Tyne NE1 4LP
R. B. Murray
Affiliation:
Raby Cross Medical Centre, Newcastle upon Tyne NE6 2FF
H. Rodgers
Affiliation:
Royal Victoria Infirmary, Newcastle upon Tyne
*
Correspondence

Abstract

A 66–year-old woman showed profound neuropsychiatric disturbance after withdrawal from prolonged corticosteroid treatment. Reintroduction of an alternative corticosteroid, at low dose, produced a return to premorbid mental state.

Type
Brief Reports
Copyright
Copyright © 1991 The Royal College of Psychiatrists 

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References

Boston Collaborative Drug Surveillance Programme (1972) Acute adverse reactions to prednisone in relation to dosage. Clinical Pharmacology and Therapeutics, 22, 155158.Google Scholar
Glynne-Jones, R., Vernon, C. & Bell, G. (1986) Is steroid psychosis preventable by divided doses? Lancet, ii, 1404.Google Scholar
Greves, J. A. (1984) Rapid onset steroid psychosis with very low dosage of prednisolone. Lancet, i, 11191120.Google Scholar
McCawley, A. (1965) Cortisone habituation – a clinical note. New England Journal of Medicine, 273, 976.Google Scholar
Minden, S. L., Orav, J. & Schildkraut, J. J. (1988) Hypomanic reactions to ACTH and prednisone treatment for multiple sclerosis. Neurology, 38, 16311634.Google Scholar
Rutgers, A. W. F., Links, T. P., Coultre, R. L., et al (1988) Behavioural disturbances after effective ACTH – treatment of the dancing eyes syndrome. Developmental Medicine and Child Neurology, 30, 408409.Google Scholar
Wolkowitz, O. M. & Rapaport, M. (1989) Long-lasting behavioural changes following prednisone withdrawal. Journal of the American Medical Association, 261, 17311732.Google ScholarPubMed
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