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Acid Metabolites from Monoamines in Cerebrospinal Fluid of Chronic Schizophrenics

Published online by Cambridge University Press:  29 January 2018

Torgny Persson
Affiliation:
Psychiatric Research Centre, St. Jörgen Hospital, Lillhágen Department of Pharmacology, University of Göteborg, Sweden
Björn-Erik Roos
Affiliation:
Psychiatric Research Centre, St. Jörgen Hospital, Lillhágen Department of Pharmacology, University of Göteborg, Sweden

Extract

Psychotropic drugs used in mental depressions or acute psychoses have been shown to interfere with monoaminergic transmission in the brain. Since it is impossible to study the metabolism of these monoamines directly in the human brain, many studies have been made on the urinary excretion of these amines and their metabolites in various mental conditions. However, few conclusive results have been obtained, because only a very small part of the urinary monoamines and their metabolites derive from the central nervous system.

Type
Biochemical and Metabolic Studies
Copyright
Copyright © Royal College of Psychiatrists, 1969 

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