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The Use of Disulfiram Implantation in Alcoholism

Published online by Cambridge University Press:  29 January 2018

J. S. Madden
Affiliation:
Regional Addiction Unit, Moston Hospital, Liverpool Road, Chester, CH2 4AA

Extract

The unpleasant reaction to alcohol experienced by patients taking disulfiram was reported twenty-four years ago (Hald and Jacobsen, 1948; Martensen-Larsen, 1948). For as long as patients continue to take oral disulfiram they may be too afraid to drink. Unfortunately in practice they often discontinue the therapy, and drink with impunity a few days later. Thus a long-acting preparation of disulfiram would be desirable.

Type
Papers
Copyright
Copyright © Royal College of Psychiatrists, 1973 

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References

Editorial (1971). Lancet, ii, 649.Google Scholar
Hald, J., and Jacobsen, E. (1948). ‘A drug sensitising the organism to ethyl alcohol.’ Lancet, ii, 1001–4.Google Scholar
Hrynkiewicz, L., Cyoanik, L., and Luszpinski, J. (1966). ‘Evaluation of personal experiences in treatment of alcoholics by Esperal implantation.’ Probl. Alkzmu. Wars., 14(5–6), 78. Abstracted in Quarterly Journal of Studies on Alcohol (1968), 29, 500.Google Scholar
Jacques, D. (1970). ‘Study of the use of disulfiram implants in the treatment of alcoholism.’ Centre International d'Alcoologie/Toxicomanies, Monogr. No. 2. Lausanne.Google Scholar
Kellam, A. M. P. (1969). ‘Disulfiram implantation.’ Journal of Alcoholism, 4, 228.Google Scholar
Kellam, A. M. P. and Wesolkski, J. (1968). ‘A case of alcoholism treated by disulfiram implantation.’ Journal of Alcoholism, 3, 3840.Google Scholar
Lynn, J. A. (1971). Personal communication.Google Scholar
Marie, C. (1955) in Jacques, D. (1970).Google Scholar
Martensen-Larsen, O. (1948). ‘Treatment of alcoholism with a sensitising drug.’ Lancet, ii, 1004–6.Google Scholar
McCance, C., and McCance, P. F. (1969). ‘Alcoholism in North East Scotland: its treatment and outcome.’ British Journal of Psychiatry, 115, 189–98.Google Scholar
Mieniewski, Z. (1967). ‘Results of treatment with Esperal implantation.’ Probl. Alkzmu. Wars., 15(4), 67. Abstracted in Quarterly Journal of Studies on Alcohol (1968), 29, 500.Google Scholar
Paillot, M., and Jacques, D. (1968). ‘A therapeutic approach to chronic alcoholism by subcutaneous implantation of disulfiram.’ Rev. Hyg. med.-soc., 16, 689–98. Abstracted in Quarterly Journal of Studies on Alcohol (1971), 32, 235.Google Scholar
Rathod, N. H., Gregory, E., Blows, D., and Thomas, G. H. (1966). ‘A two-year follow-up study of alcoholic patients.’ British Journal of Psychiatry, 112, 683–92.Google Scholar
Swinson, R. P. (1970). ‘Disulfiram implant.’ Journal of Alcoholism, 5, 40.Google Scholar
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