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The Treatment of Neuroleptic Malignant Syndrome are Dantrolene and Bromocriptine Useful Adjuncts to Supportive Care?

Published online by Cambridge University Press:  02 January 2018

Patricia I. Rosebush ,
Thomas Stewart  and
Michael F. Mazurek
Patricia I. Rosebush*
Affiliation:
Department of Psychiatry, McMaster University Medical Centre, Hamilton, Ontario, Canada L8N 3ZS
Thomas Stewart
Affiliation:
Department of Psychiatry, Beth Israel Hospital, Harvard University, Boston, Massachusetts, USA
Michael F. Mazurek
Affiliation:
Division of Neurology, Departments of Medicine and Biomedical Sciences, McMaster University Medical Centre, Hamilton, Ontario
*
∗Correspondence
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Abstract

In a prospective study of 20 patients with NMS, those who received dantrolene (2 patients) or bromocriptine (2 patients) or both (4 patients) tended to have a more prolonged course of illness and a greater incidence of sequelae than those treated with supportive care alone. These results do not indicate a useful role for dantrolene or bromocriptine in the treatment of NMS.

Type
Brief Reports
Information
The British Journal of Psychiatry , Volume 159 , Issue 5 , November 1991 , pp. 709 - 712
Copyright
Copyright © 1991 The Royal College of Psychiatrists 

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