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Relationships Among Negative, Positive, and Depressive Symptoms in Schizophrenia and Psychotic Depression

Published online by Cambridge University Press:  02 January 2018

Kenji W. Sax ,
Stephen M. Strakowski ,
Paul E. Keck Jr. ,
Vidya H. Upadhyaya ,
Scott A. West  and
Susan L. McElroy
Kenji W. Sax*
Affiliation:
University of Cincinnati College of Medicine, Cincinnati, Ohio
Stephen M. Strakowski
Affiliation:
University of Cincinnati College of Medicine, Cincinnati, Ohio
Paul E. Keck Jr.
Affiliation:
University of Cincinnati College of Medicine, Cincinnati, Ohio
Vidya H. Upadhyaya
Affiliation:
University of Cincinnati College of Medicine, Cincinnati, Ohio
Scott A. West
Affiliation:
Florida Hospital, Orlando, Florida
Susan L. McElroy
Affiliation:
University of Cincinnati College of Medicine, Cincinnati, Ohio
*
Dr Sax, Biological Psychiatry Program, Department of Psychiatry, University of Cincinnati College of Medicine, 231 Bethesda Avenue (ML 559), Cincinnati, Ohio, 45267-0559, USA. Fax: (513)558-2882
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Abstract

Background

We examined relationships among positive, negative, and depressive symptoms in schizophrenia and major depression with psychosis.

Method

Patients with schizophrenia (n = 17) and major depression and psychotic features (n = 25), with no prior psychopharmacologic treatment were assessed on scales measuring positive psychotic, negative, and depressive symptoms.

Results

Analyses revealed that depressive symptoms positively correlated with anhedonia/asociality and avolition/apathy in both patient groups. Positive psychotic symptoms significantly correlated with depressive symptoms in the schizophrenic group.

Conclusions

Several specific symptoms used in defining both depressive and negative syndrome constructs appear to be shared. The relationship between positive symptoms and depression in schizophrenia and not psychotic depression suggests the severity of depression may be involved in this relationship.

Type
Papers
Information
The British Journal of Psychiatry , Volume 168 , Issue 1 , January 1996 , pp. 68 - 71
Copyright
Copyright © 1996 The Royal College of Psychiatrists 

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