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Rationale and design

PRiSM Psychosis Study 1

Published online by Cambridge University Press:  02 January 2018

Graham Thornicroft ,
Geraldine Strathdee ,
Michael Phelan ,
Frank Holloway ,
Til Wykes ,
Graham Dunn ,
Paul McCrone ,
Morven Leese ,
Sonia Johnson  and
George Szmukler
Graham Thornicroft*
Affiliation:
Section of Community Psychiatry (PRiSM), Institute of Psychiatry, London
Geraldine Strathdee
Affiliation:
Oxleas NHS Trust, Laurel House, 2 Blean Grove, Penge
Michael Phelan
Affiliation:
Charing Cross Hospital, Fulham Palace Road, London
Frank Holloway
Affiliation:
Maudsley Hospital, Denmark Hill, London
Til Wykes
Affiliation:
Department of Psychology, Institute of Psychiatry, London
Graham Dunn
Affiliation:
University of Manchester, Oxford Road, Manchester
Paul McCrone
Affiliation:
Section of Community Psychiatry (PRiSM), Institute of Psychiatry, London
Morven Leese
Affiliation:
Section of Community Psychiatry (PRiSM), Institute of Psychiatry, London
Sonia Johnson
Affiliation:
Department of Psychiatry & Behavioural Sciences, University College London Medical School, 48 Riding House Street, London
George Szmukler
Affiliation:
Section of Community Psychiatry (PRiSM), Institute of Psychiatry, De Crespigny Park, London
*
Professor Graham Thornicroft, Section of Community Psychiatry (PRiSM), Institute of Psychiatry, De Crespigny Park, London SE5 8AF. Tel: 0171 919 2610; Fax: 0171 277 1462
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Abstract

Background

This paper sets out the rationale for the PRiSM Psychosis Study, and the research design used. Nine accompanying papers present the main results. The questions addressed by the PRiSM Psychosis Study are: can the gains of experimental studies which have demonstrated benefits arising from treatment by community mental health teams be translated to routine settings? If so, are the benefits diluted in ordinary clinical practice? What are the costs?

Method

A prospective non-randomised controlled trial of two types of community mental health service, in two phases: case identification followed by patient interviews. For the case identification the research team conducted the complete ascertainment of all prevalent cases of psychosis in the two study catchment areas in the index year (1991–1992). From all 514 patients with psychotic disorders thus identified, 302 were randomly allocated for interview, along with a key informant clinician and a carer. Interviews were undertaken at two time points, two years apart.

Results

This paper presents the socio-demographic, clinical and ethnic characteristics of the patients.

Conclusions

The people with psychosis interviewed for the PRiSM Psychosis Study are representative of the whole epidemiologically based patient population identified.

Type
PRiSM Psychosis Study
Information
The British Journal of Psychiatry , Volume 173 , Issue 5 , November 1998 , pp. 363 - 370
Copyright
Copyright © 1998 The Royal College of Psychiatrists 

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Footnotes

Declaration of interest

Funding provided by the Bethlem & Maudsley NHS Trust.

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