Hostname: page-component-cd9895bd7-fscjk Total loading time: 0 Render date: 2024-12-25T06:53:27.363Z Has data issue: false hasContentIssue false
  • English
  • Français

Mood and Behavioural Changes with Progestational Agents

Published online by Cambridge University Press:  29 January 2018

Francis J. Kane Jr. ,
Robert J. Daly ,
John A. Ewing  and
Martin H. Keeler
Martin H. Keeler
Affiliation:
Chapel Hill, North Carolina
Get access Rights & Permissions [Opens in a new window]

Extract

Steroid hormones may produce a wide variety of psychiatric syndromes (1), (2), and the progestational steroids are no exception. We were alerted to this by the occurrence of an acute schizophrenic psychosis following the withdrawal of 30 mg. Enovid (Enavid) daily, which was being used to control endometriosis (3). The patient's psychotic symptoms showed remission with drug replacement and relapse on placebo.

Type
Research Article
Information
The British Journal of Psychiatry , Volume 113 , Issue 496 , March 1967 , pp. 265 - 268
Copyright
Copyright © Royal College of Psychiatrists, 1967 

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

1. Rome, H. P., and Braceland, F. J. (1952). “The psychological response to A.C.T.H., cortisone, hydrocortisone, and related steroid substances.” Am. J. Psychiat., 108, 641–651.CrossRefGoogle Scholar
2. Glaser, G. H. (1953). “Psychiatric reactions induced by corticotrophin (A.C.T.H.), and cortisone.” Psychosom. Med., 15, 280–291.CrossRefGoogle Scholar
3. Keeler, M. H., Kane, F. J., and Daly, R. (1964). “An acute schizophrenic episode following abrupt withdrawal of Enovid in a patient with previous post-partum psychiatric disorder.” Am. J. Psychiat., 120, 1123–1124.CrossRefGoogle Scholar
4. Grant, Ellen C. G. (1965). “Relation of arterioles in the endometrium to headache from oral contraceptives.” Lancet, i, 1143–1144.CrossRefGoogle Scholar
5. Lorraine, J. A., Bell, E. T., Harkness, R. A., Mears, E., and Jackson, M. C. N. (1963). “Oral progestational agents.” Ibid., ii, 902–905.Google Scholar
6. Gilbert, M., Rotstein, J., Cunningham, C., Estrin, E., Davidson, A., and Pineus, G. (1964). “Norethynodrel with mestranol in treatment of rheumatoid arthritis.” J. Amer. med. Assoc., 190, 235.CrossRefGoogle ScholarPubMed
7. Aurell, M., Cramer, K., and Rybo, G. (1966). “Serum lipids and lipo-proteins during long-term administration of an oral contraceptive.” Lancet, i, 291–293.CrossRefGoogle Scholar
8. Gibbs, F. A., and Reid, D. E. (1942). “The electroencephalogram in pregnancy.” Am. J. Obstet. & Gyn., 44, 672–675.CrossRefGoogle Scholar
9. Woolley, D. E., and Timiras, P. S. (1962). “The gonad-brain relationship: effects of female sex on electroshock convulsions in the rat.” Endocrinology, 70, 196–209.CrossRefGoogle ScholarPubMed
10. Sawyer, C. H. (1963). “Neuroendocrine blocking agents: discussion.” In: Advances in Neuroendocrinology. University of Illinois Press, p. 451–459.Google Scholar
11. Benedek, T., and Rubenstein, G. B. (1939). “The correlations between ovarian activity and psychodynamic processes, I. the ovulation phase.” Psychosom. Med., 1, 245–270.CrossRefGoogle Scholar
12. Hampson, J., and Hampson, J. (1961). “The ontogeny of sexual behavior in man.” In: Sex and Internal Secretions. Ed. Young, W. Ch. 23, p. 1401–1422, Baltimore, Md.: Williams & Williams Co.Google Scholar
13. Reported in “Does the pill a day drive libido away?” Medical World News, May 20, 1966.Google Scholar
14. Kane, F. J., Jarman, W. H., Keeler, M. H., and Ewing, J. A. (1966). Presented at the Annual Meeting of the American Psychiatric Association, May, 1966.Google Scholar
Submit a response

eLetters

No eLetters have been published for this article.