Hostname: page-component-586b7cd67f-2brh9 Total loading time: 0 Render date: 2024-11-30T20:09:48.076Z Has data issue: false hasContentIssue false
  • English
  • Français

Monozygotic Twins Concordant for Infantile Autism: Follow-up

Published online by Cambridge University Press:  29 January 2018

Magda Campbell ,
Cristina Dominijanni  and
Barry Schneider
Magda Campbell
Affiliation:
Department of Psychiatry, New York University Medical Center, 550 First Avenue, New York, New York 10016, USA
Cristina Dominijanni
Affiliation:
Department of Psychiatry, New York University Medical Center, 550 First Avenue, New York, New York 10016, USA
Barry Schneider
Affiliation:
Department of Psychiatry, New York University Medical Center, 550 First Avenue, New York, New York 10016, USA
Get access Rights & Permissions [Opens in a new window]

Extract

This paper presents a well-documented case of monozygotic male twins concordant for infantile autism, with a twelve-year follow-up. Assessments include birth records, laboratory studies, physical measurements, psychometrics and quantifiable behavioural ratings by independent raters using multiple scales. Possible aetiological factors of infantile autism, as well as outcome are discussed.

Type
Research Article
Information
The British Journal of Psychiatry , Volume 131 , Issue 6 , December 1977 , pp. 616 - 622
Copyright
Copyright © Royal College of Psychiatrists, 1977 

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Burdock, E. I. & Hardesty, A. S. (1967) Contrasting behavior patterns of mentally retarded and emotionally disturbed children. In Psychopathology of Mental Development (eds Zubin, J. and Jervis, G. A.). New York: Grune & Stratton.Google Scholar
Campbell, M. (1977) Demographic parameters of disturbed children: a template to the CPDI and CSH, its rationale and significance. Psychopharmacology Bulletin, 13, 30–3.Google Scholar
Cheek, D. G., Migeon, C. J. & Mellits, E. D. (1968) The concept of biologic age. In Human Growth (ed. Cheek, D. B.). Philadelphia: Lea & Febiger.Google Scholar
Creak, M. (1964) Schizophrenic syndrome in childhood. Developmental Medicine and Child Neurology, 4, 530–5.Google Scholar
DeMyer, M. K., Barton, S., DeMyer, W. E., Norton, J. A., Allen, J. & Steele, R. (1973) Prognosis in autism: a follow-up study. Journal of Autism and Childhood Schizophrenia, 3, 199–246.Google Scholar
Diagnostic and Statistical Manual of Mental Disorders (DSM II) (1968) Second edition. Washington, D.C.: American Psychiatric Association.Google Scholar
Dunn, P. M. (1965) Some perinatal observations in twins. Developmental Medicine and Child Neurology, 7, 121–34.Google Scholar
Eisenberg, L. (1956) The autistic child in adolescence. American Journal of Psychiatry, 112, 607–12.Google Scholar
Folstein, S. & Rutter, M. (1977) Infantile autism: a genetic study of 21 twin pairs. Journal of Child Psychology and Psychiatry, Vol 18, No. 4.Google Scholar
Hanson, D. R. & Gottesman, I. I. (1976) The genetics, if any, of infantile autism and childhood schizophrenia. Journal of Autism and Childhood Schizophrenia, 6, 209–34.Google Scholar
Kallman, F. J. & Roth, B. (1956) Genetic aspects of preadolescent schizophrenia. American Journal of Psychiatry, 112, 559–606.Google Scholar
Kanner, L. (1943) Autistic disturbances of affective contact. Nervous Child, 2, 217–50.Google Scholar
Kanner, L. (1971) Follow-up study of eleven autistic children originally reported in 1943. Journal of Autism and Childhood Schizophrenia, 1, 119–45.Google Scholar
Lockyer, L. & Rutter, M. (1969) A five to fifteen year follow-up study of infantile psychosis. III. Psychological aspects. British Journal of Psychiatry, 115, 865–82.Google Scholar
Lotter, V. (1974) Social adjustment and placement of autistic children in Middlesex: a follow-up study. Journal of Autism and Childhood Schizophrenia, 4, 11–32.CrossRefGoogle ScholarPubMed
McQuaid, P. E. (1975) Infantile autism in twins. British Journal of Psychiatry, 127, 530–4.Google Scholar
Ornitz, E. M. (1973) Childhood autism: a review of the clinical and experimental literature. California Medicine, 118, 21–47.Google Scholar
Psychopharmacology Bulletin (1973) Pharmacotherapy of Children. Special Issue.Google Scholar
Ritvo, E. R. (1976) Autism. Diagnosis, Current Research and Management. New York: Spectrum Publications, Inc.Google Scholar
Rutter, M. (1967) Psychotic disorders in early childhood. In Recent Developments in Schizophrenia (eds Coppen, A. and Walk, A.), pp 133–58. British Journal of Psychiatry Special Publication No. 1. Ashford, Kent: Headley Bros Ltd.Google Scholar
Rutter, M. (1976) Clinical characteristics of autism. Paper presented at International Symposium on Autism, St Gallen, Switzerland, 12–15 July 1976.Google Scholar
Rutter, M. Greenfeld, D. & Lockyer, L. (1967) A five to fifteen year follow-up study of infantile psychosis. II. Social and behavioural outcome. British Journal of Psychiatry, 113, 1183–99.Google Scholar
Torrey, E. F., Hersh, S. P. & McCabe, K. D. (1975) Early childhood psychosis and bleeding during pregnancy. Journal of Autism and Childhood Schizophrenia, 5, 287–97.Google Scholar
Vaillant, G. E. (1963) Twins discordant for early infantile autism. Archives of General Psychiatry, 9, 163–7.Google Scholar
Submit a response

eLetters

No eLetters have been published for this article.