Hostname: page-component-586b7cd67f-dlnhk Total loading time: 0 Render date: 2024-12-04T09:25:59.176Z Has data issue: false hasContentIssue false
  • English
  • Français

The Effect of Age and Residential Placement on Adaptive Behaviour of Adults with Down's Syndrome

Published online by Cambridge University Press:  02 January 2018

Richard A. Collacott
Richard A. Collacott*
Affiliation:
Department of Psychiatry, University of Leicester
*
∗Frith Hospital, Groby Road, Leicester LE3 9QF
Get access Rights & Permissions [Opens in a new window]

Abstract

Through widespread enquiry, the population of adults with Down's syndrome (aged over 18 years) in Leicestershire was estimated at 376. For 315 of these (83.8%), the immediate carer was invited to complete the Adaptive Behavior Scale (ABS). Completed ABS assessments were obtained on 81.9% of the adult population with Down's syndrome in the county. Additional information concerning residential history was obtained. When the sample was divided into five cohorts on the basis of age when the ABS assessment took place, an exponential decline in ability was observed. Deterioration in most domains of the ABS achieved statistical significance in the cohort aged 50–59, and in all domains in those aged 60 and over. The deterioration in global skills in older cohorts was attributed to ageing (and thereby probably Alzheimer's disease). Institutional placement was associated with low scores in younger groups only.

Type
Papers
Information
The British Journal of Psychiatry , Volume 161 , Issue 5 , November 1992 , pp. 675 - 679
Copyright
Copyright © 1992 The Royal College of Psychiatrists 

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Bhaumik, S., Collacott, R. A., Garrick, P., et al (1991) Effect of thyroid stimulating hormone on adaptive behaviour in Down's syndrome. Journal of Mental Deficiency Research, 35, 512–520.Google ScholarPubMed
Blessed, G., Tomlinson, B. E. & Roth, M. (1968) The association between quantitative measures of dementia and of degenerative changes in the cerebral grey matter of elderly subjects. British Journal of Psychiatry, 144, 797.Google Scholar
Bleuler, E. (1916) Lehrbuch Der Psychiatrie (trans. Brill, A. A. as Textbook of Psychiatry (1924) Dover Publications).Google Scholar
Collacott, R. A. & Cooper, S.-A. (1992) Adaptive behaviour after depressive illness in Down's syndrome. Journal of Nervous and Mental Disease, 180, 468–470.CrossRefGoogle ScholarPubMed
Dalton, A. J., Crapper, D. R. & Schlotterer, G. R. (1974) Alzheimer's disease in Down's syndrome: visual retention deficits. Cortex, 10, 336–337.CrossRefGoogle ScholarPubMed
Dalton, A. J., Crapper, D. R. (1977) Down's syndrome and ageing of the brain. In Research to Practice in Mental Retardation (ed. P. Mittler), pp. 391–400. Baltimore: University Park Press.Google Scholar
Ellis, W. G., McCulloch, J. R. & Corlby, C. L. (1974) Presenile dementia in Down's syndrome. Neurology, 24, 101–106.CrossRefGoogle ScholarPubMed
Fenner, M. E., Hewitt, K. & Torpy, D. M. (1987) Down's syndrome: intellectual and behavioural functioning during adulthood. Journal of Mental Deficiency Research, 31, 241–249.Google ScholarPubMed
Fogelman, C. J. (1975) AAMD Adaptive Behavior Scale Manual. Washington, DC: American Association on Mental Deficiency.Google Scholar
Haberland, C. (1969) Alzheimer's disease in Down's syndrome. Acta Neurologica Belgica, 69, 369–380.Google Scholar
Haxby, J. V. (1989) Neuropsychological evaluation of adults with Down's syndrome: patterns of selective impairment in non-demented old adults. Journal of Mental Deficiency Research, 33, 193–210.Google ScholarPubMed
Malamud, N. (1972) Organic brain syndrome associated with ageing. In Ageing and the Brain (ed. C. M. Gaitz). New York: Plenum.Google Scholar
Mani, C. (1988) Hypothyroidism in Down's syndrome. British Journal of Psychiatry, 153, 102–104.Google Scholar
Miniszek, N. A. (1983) Development of Alzheimer's disease in Down's syndrome individuals. American Journal of Mental Deficiency, 87, 377–385.Google Scholar
Owens, D., Dawson, J. C. & Losin, S. (1971) Alzheimer's disease in Down's syndrome. American Journal of Mental Deficiency, 75, 606–612.Google Scholar
Thase, M. E., Liss, L., Smeltzer, D., et al (1982) Clinical evaluation of dementia in Down's syndrome: a preliminary report. Journal of Mental Deficiency Research, 26, 239–244.Google ScholarPubMed
Thase, M. E., Tigner, R., Smeltzer, D. J., et al (1984) Age-related neuropsychological deficits in Down's syndrome. Biological Psychiatry, 19, 571–585.Google Scholar
Whalley, L. J. (1982) Dementia of Down's syndrome and its relevance to aetiological studies of Alzheimer's disease. Annals of New York Accademy of Sciences, 396, 39–53.CrossRefGoogle ScholarPubMed
Wisniewski, K. E., Wisniewski, H. M. & Wen, G. Y. (1985) Occurrence of neuropathological changes and dementia in Alzheimer's disease in Down's syndrome. Annals of Neurology, 17, 278–282.Google Scholar
Zigman, W. B., Schupf, N., Lubin, R. A., et al (1987) Premature regression of adults with Down's syndrome. American Journal of Mental Deficiency, 92, 161–168.Google Scholar
Submit a response

eLetters

No eLetters have been published for this article.