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The Effect of Activation Procedures on Neuroleptic-Induced Akathisia

Published online by Cambridge University Press:  02 January 2018

W. Wolfgang Fleischhacker*
Affiliation:
Department of Biological Psychiatry
Carl H. Miller
Affiliation:
Department of Psychiatry, Innsbruck University Clinics, Anichstrasse 35, A-6020 Innsbruck, Austria
Christian Barnas
Affiliation:
Department of Psychiatry, Innsbruck University Clinics, Anichstrasse 35, A-6020 Innsbruck, Austria
Ken Bergmann
Affiliation:
Hillside Hospital, Division of Long Island Jewish Medical Center, New York, USA
Robert Perovich
Affiliation:
Hillside Hospital, Division of Long Island Jewish Medical Center, New York, USA
Jose Ma. J. Alvir
Affiliation:
Hillside Hospital, Division of Long Island Jewish Medical Center, New York, USA
Jeffrey A. Lieberman
Affiliation:
Hillside Hospital, Division of Long Island Jewish Medical Center, New York, USA
John M. Kane
Affiliation:
Hillside Hospital, Division of Long Island Jewish Medical Center, New York, USA
*
Correspondence

Abstract

Two studies have been performed to evaluate the effect of activation tasks on neuroleptic-induced akathisia (NIA). In the first sample (30 patients) we found a consistent increase of symptoms during mental activation while motor activation led to a decrease. In a second study 34 patients with the same diagnosis were evaluated, using slightly different statistical procedures: while the effects of motor activation were corroborated, mental activation did not change NIA. Since mental and motor activation are usually considered to increase tardive dyskinesia and Parkinsonism, these measures might be helpful in differentiating NIA from other antipsychotic-induced movement disorders.

Type
Research Article
Copyright
Copyright © The Royal College of Psychiatrists 

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References

American Psychiatric Association (1987) Diagnostic and Statistical Manual of Mental Disorders (3rd edn, revised) (DSM–III–R). Washington, DC: APA.Google Scholar
Barnes, T. R. & Braude, W. M. (1985) Akathisia variants and tardive dyskinesia. Archives of General Psychiatry, 42, 874878.Google Scholar
Braude, W. M., Barnes, T. R. & Gore, S. M. (1983) Clinical characteristics of akathisia: a systematic investigation of acute psychiatric inpatient admissions. British Journal of Psychiatry, 143, 139150.Google Scholar
Fleischhacker, W. W., Bergmann, K. J., Perovich, R., et al (1989) The Hillside Akathisia Scale: a new rating instrument for neuroleptic induced akathisia. Psychopharmacology Bulletin, 25, 222226.Google Scholar
Fleischhacker, W. W., Miller, C. H., Schett, P., et al (1991) The Hillside Akathisia Scale: a reliability comparison of the English and German version. Psychopharmacology, 105, 141144.CrossRefGoogle Scholar
Gibb, W. R. G. & Lees, A. J. (1986) The clinical phenomenon of akathisia. Journal of Neurology, Neurosurgery and Psychiatry, 49, 861866.Google Scholar
Guy, W. E. (1976) Assessment Manual for Psychopharmacology, pp. 534537. Washington, DC: US Government Printing Office.Google Scholar
Munetz, M. R. & Cornes, C. L. (1983) Distinguishing akathisia and tardive dyskinesia: A review of the literature. Journal of Clinical Psychopharmacology, 3, 343350.Google Scholar
Stahl, S. (1985) Akathisia and tardive dyskinesia. Archives of General Psychiatry, 42, 915917.Google Scholar
Van Putten, T., May, P. R. A. & Marder, S. R. (1984) Akathisia with haloperidol and thiothixene. Archives of General Psychiatry, 41, 10261039.Google Scholar
Weiden, P. J., Mann, J. J., Haas, G., et al (1987) Clinical nonrecognition of neuroleptic-induced movement disorders: a cautionary study. American Journal of Psychiatry, 144, 11481153.Google ScholarPubMed
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