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The Course of Tardive Dyskinesia in Patients on Long-Term Neuroleptics

Published online by Cambridge University Press:  02 January 2018

J. A. Bergen ,
E. A. Eyland ,
J. A. Campbell ,
P. Jenkings ,
K. Kellehear ,
A. Richards  and
P. J. V. Beumont
J. A. Bergen*
Affiliation:
Department of Community Medicine, Royal Prince Alfred Hospital
E. A. Eyland
Affiliation:
School of Economic and Financial Studies, Maquarie University
J. A. Campbell
Affiliation:
Department of Community Medicine, Royal Prince Alfred Hospital
P. Jenkings
Affiliation:
Department of Community Medicine, Royal Prince Alfred Hospital
K. Kellehear
Affiliation:
Department of Psychiatry, University of Sydney
A. Richards
Affiliation:
Department of Psychiatry, University of Sydney
P. J. V. Beumont
Affiliation:
Department of Psychiatry, University of Sydney
*
∗Missenden Road, Camperdown, NSW 2050, Australia
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Abstract

Results are presented of five consecutive annual examinations using the Abnormal Involuntary Movement Scale for 101 community-based chronic psychiatric patients. These 101 patients had a history of longer and more consistent neuroleptic treatment than the 231 patients who initially entered the study, so no conclusions about prevalence of TD can be drawn. At each examination two-thirds of this group showed signs of TD; however, only 45% were TD positive at most examinations and 24% were best described as having fluctuating TD status. Of those patients who were consistently TD positive, 82% showed no overall significant change in summed AIMS scores, 11% improved and 7% became worse.

Type
Papers
Information
The British Journal of Psychiatry , Volume 154 , Issue 4 , April 1989 , pp. 523 - 528
Copyright
Copyright © Royal College of Psychiatrists, 1989 

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References

Barnes, T. R. E., Kidger, T. & Gore, S. M. (1983) Tardive dyskinesia: a 3-year follow-up study. Psychological Medicine, 13, 71–81.Google Scholar
Barron, E. T. & McCreadie, R. G. (1983) One year follow-up of tardive dyskinesia (letter). British Journal of Psychiatry, 143, 423–424.Google Scholar
Bergen, J. A., Griffiths, D. A., Rey, J. M., et al (1984) Tardive dyskinesia: fluctuating patient or fluctuating rater. British Journal of Psychiatry, 144, 498–502.Google Scholar
Casey, D. E. & Toenniessen, L. M. (1983) Neuroleptic treatment in tardive dyskinesia: can it be developed into a clinical strategy for long-term treatment? Modern Problems in Pharmacopsychiatry, 21, 65–79.Google Scholar
Chouinard, G., Annable, L., Mercier, P., et al (1986) A five-year follow-up study of tardive dyskinesia. Psychopharmacology Bulletin, 22, 259–263.Google ScholarPubMed
Dixon, W. J. (1983) BMDP Statistical Software, 1983 printing with additions. Berkeley: University of California Press.Google Scholar
Doonagi, D. R.; Jeste, D. V., Jape, N. M., et al (1982) Tardive dyskinesia in India: a prevalence study. Journal of Clinical Psychopharmacology, 2, 341–344.Google Scholar
Gardos, G., Samu, I., Kallos, M., et al (1980) Absence of severe tardive dyskinesia in Hungarian schizophrenic outpatients. Psychopharmacology, 71, 29–34.Google Scholar
Gardos, G., Perenyi, A., Cole, J. O., et al (1983) Tardive dyskinesia: changes after three years. Journal of Clinical Psychopharmacology, 3, 315–318.CrossRefGoogle ScholarPubMed
Gardos, G., Cole, J. O., Perenyi, A., et al (1985) Five year follow-up study of tardive dyskinesia. In Chronic Treatments in Neuropsychiatry (eds Kemali, D. & Racagni, G.). New York: Raven Press.Google Scholar
Guy, W. (1976) ECDEU Assessment Manual for Psychopharmacology, revised edn. Washington DC: US Department of Health, Education and Welfare.Google Scholar
Jeste, D. V., Jeste, S. D. & Wyatt, J. W. (1983) Reversible tardive dyskinesia: implications for therapeutic strategy and prevention of tardive dyskinesia. Modern Problems in Pharmacopsychiatry, 21, 34–48.Google Scholar
Kane, J. M. & Schooler, N. R. (1980) Tardive dyskinesia workgroup report. Psychopharmacology Bulletin, 16, 35–36.Google Scholar
Kane, J. M., Rifkin, A., Woerner, M., et al (1983) Low-dose neuroleptic treatment in outpatient schizophrenics – I. Preliminary results for relapse. Archives of General Psychiatry, 40, 893–896.Google Scholar
Kane, J. M., Woerner, M., Weinhold, P., et al (1984) Incidence of tardive dyskinesia: five-year data from a prospective study. Psychopharmacology Bulletin, 20, 387–389.Google Scholar
Marder, S. R., Van Putten, T., Mintz, J., et al (1987) Low- and conventional-dose maintenance therapy with fluphenazine decanoate: two year outcome. Archives of General Psychiatry, 44, 518–521.Google Scholar
Mason, A. S. & Granacher, R. P. (1980) Clinical Handbook of Antipsychotic Drug Therapy. New York: Brunner/Mazel.Google Scholar
Ryan, T. A., Joiner, B. L. & Ryan, B. F. (1976) Minitab Student Handbook. Massachusetts: Duxbury Press.Google Scholar
Schooler, N. R. & Kane, J. M. (1982) Research Diagnoses for Tardive Dyskinesia. Archives of General Psychiatry, 39, 486–487.Google ScholarPubMed
Seeman, M. V. (1981) Tardive dyskinesia: two-year recovery. Comprehensive Psychiatry, 22, 189–192.CrossRefGoogle ScholarPubMed
Smith, J. M., Burke, M. A. & Moon, C. O. (1981) Long term changes in AIMS ratings in relation to medication history. Psychopharmacology Bulletin, 17, 120–121.Google Scholar
Yassa, R., Nair, V. & Schwartz, G. (1984) Tardive dyskinesia: a two-year follow-up study. Psychosomatics, 25, 852–855.CrossRefGoogle ScholarPubMed
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