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Chromosome Findings in Chronic Psychotic Patients

Published online by Cambridge University Press:  29 January 2018

J. M. Anders ,
G. Jagiello ,
P. E. Polani ,
F. Giannelli ,
J. L. Hamerton  and
D. M. Leiberman
J. M. Anders
Affiliation:
Institute of Cardiology, Wimpole Street, London, W.1
G. Jagiello
Affiliation:
1 F3 HD-8443-01 REP, Paediatric Research Unit, Guy's Hospital Medical School, London, S.E.1
P. E. Polani
Affiliation:
University of London, Paediatric Research Unit, Guy's Hospital Medical School, London, S.E.1
F. Giannelli
Affiliation:
Paediatric Research Unit, Guy's Hospital Medical School, London, S.E.1
J. L. Hamerton
Affiliation:
Paediatric Research Unit, Guy's Hospital Medical School, London, S.E.1
D. M. Leiberman
Affiliation:
Bexley Hospital, Dartford Heath, Bexley, Kent
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Extract

The observation of a higher incidence of sex-chromosome abnormalities amongst patients in mental deficiency and subnormality institutions than in the general population (Maclean et al., 1962; Court Brown et al., 1964) suggested that a sex chromatin survey of a theoretically related chronic psychotic population might be of interest. Mott (1919) observed a high frequency of testicular atrophy in dementia praecox, particularly in patients dying in early adolescence, and Forster (quoted by Mott, 1919) reported on the ovarian findings in similarly affected women. Hemphill et al. (1944) found a high incidence of testicular atrophy in a series of ninety male schizophrenic patients.

Type
Research Article
Information
The British Journal of Psychiatry , Volume 114 , Issue 514 , September 1968 , pp. 1167 - 1174
Copyright
Copyright © Royal College of Psychiatrists, 1968 

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