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The Benzodiazepine Receptor and its Role in Anxiety

Published online by Cambridge University Press:  02 January 2018

Sandra E. File
Sandra E. File*
Affiliation:
MRC Neuropharmacology Research Group, The School of Pharmacy, University of London, Brunswick Square, London WC1N 1AX
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Extract

Ten years ago, specific high-affinity binding sites for benzodiazepines (BDZs) were found in the brain (Mohler & Okada, 1977; Squires & Braestrup, 1977). These binding sites are believed to be the primary site of action of BDZs and are found on the same protein as GABA receptors. GABA is the main inhibitory neurotransmitter in the brain.

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Annotation
Information
The British Journal of Psychiatry , Volume 152 , Issue 5 , May 1988 , pp. 599 - 600
Copyright
Copyright © Royal College of Psychiatrists, 1988 

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