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Anticholinesterase Drugs and Epileptic Seizures

Published online by Cambridge University Press:  29 January 2018

Stoyan Ikonomoff
Stoyan Ikonomoff*
Affiliation:
Formerly at Plovdiv Hospital, Plovdiv, Bulgaria
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Extract

Despite the views of many authors that migraine and epilepsy are unrelated phenomena, there is much evidence to the contrary. Davidenkov (1934) studied fifty parents with epilepsy, twenty-six of whose children had migraine. Barolin (1966) and Janzen (1969) also present evidence of a high incidence of migraine in epileptics. Owing to the success in treating migraine with anticholinesterases syntostigmin and nivalin (Ikonomoff, 1961, 1967, 1968), and the possible relationship between migraine and epilepsy, the same anticholinesterase drugs were administered to epileptics. Tentative and careful studies with syntostigmin and nivalin seemed to show that these anticholinesterases could be given with safety and apparent success. A study was therefore. undertaken of the effects of syntostigmin.

Type
Abstract
Information
The British Journal of Psychiatry , Volume 117 , Issue 541 , December 1970 , pp. 679 - 680
Copyright
Copyright © The Royal College of Psychiatrists, 1970 

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