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Recent advances in cerebrovascular disease

Published online by Cambridge University Press:  17 November 2008

Graeme J Hankey
Graeme J Hankey*
Affiliation:
Royal Perth Hospital, Australia
*
Graeme J Hankey, Department of Neurology, Royal Perth Hospital, MWellington Street, Perth, Western Australia 6001, Australia.
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Abstract

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Type
Clinical geriatrics
Information
Reviews in Clinical Gerontology , Volume 2 , Issue 3 , August 1992 , pp. 187 - 206
Copyright
Copyright © Cambridge University Press 1992

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References

1Brown, MM, Hachinski, V.Vascular dementia. Curr Op Neurol Neurosurg 1989; 2: 78–84.Google Scholar
2Dennis, MS, Bamford, JM, Sandercock, PAG, Warlow, CP.A comparison of risk factors and prognosis for transient ischaemic attacks and minor ischaemic strokes. The Oxfordshire Community Stroke Project. Stroke 1989; 20: 1494–99.CrossRefGoogle ScholarPubMed
3Bamford, JM. The classification and natural history of acute cerebrovascular disease [Dissertation]. Manchester: University of Manchester, 1986.Google Scholar
4Martin, J, Meltzer, H, Elliot, D.OPCS surveys of disability in Great Britain, report 1, the prevalence of disability among adults. London: HMSO, 1988.Google Scholar
5Bamford, J, Sandercock, P, Dennis, M et al. A prospective study of acute cerebrovascular disease in the community: the Oxfordshire Community Stroke Project 1981–1986. Methodology, demography and incident cases of first-ever stroke. J Neurol Neurosurg Psychiatry 1988; 51: 1373–80.Google Scholar
6Bamford, J, Sandercock, P, Dennis, M, Burn, J, Warlow, C. A prospective study of acute cerebrovascular disease in the community: the Oxfordshire Community Stroke Project 1981–1986. Incidence, case fatality rates and overall outcome at one year of cerebral infarction, primary intracerebral haemorrhage and subarachnoid haemorrhage. J Neurol Neurosurg Psychiatry 1990; 53: 16–22.CrossRefGoogle ScholarPubMed
7Wade, DT, Langton Hewer, R, Skilbeck, CE, David, RM.Stroke. A critical approach to diagnosis, treatment and management. London: Chapman & Hall, 1985.Google Scholar
8Dennis, M, Bamford, J, Sandercock, P, Warlow, C.Prognosis of transient ischaemic attacks in the Oxfordshire Community Stroke Project. Stroke 1990; 21: 848–53.CrossRefGoogle ScholarPubMed
9Hankey, GJ, Slattery, JM, Warlow, CP.The prognosis of hospital-referred transient ischaemic attacks. J Neurol Neurosurg Psychiatry 1991; 54: 793–802.CrossRefGoogle ScholarPubMed
10Dennis, MS, Bamford, JM, Sandercock, PAG, Warlow, CP.Incidence of transient ischaemic attacks in Oxfordshire, England. Stroke 1989; 20: 333–39.CrossRefGoogle ScholarPubMed
11Scheinberg, P.Dementia due to vascular disease – a multifactorial disorder. Stroke 1988; 19: 1291–99.CrossRefGoogle ScholarPubMed
12Calanchini, PR, Swanson, PD, Gotshall, RA et al. Cooperative study of hospital frequency and character of transient ischaemic attacks: IV. The reliability of diagnosis. JAMA 1977; 238: 2029–33.Google Scholar
13Kraaijeveld, CL, Van Gijn, J, Schouten, HJA, Staal, A.Interobserver agreement for the diagnosis of transient ischaemic attacks. Stroke 1984; 15: 723–25.CrossRefGoogle Scholar
14Reggia, JA, Tabb, R, Price, TR, Banko, M, Hebel, R.Computer-aided assessment of transient ischaemic attacks. A clinical evaluation. Arch Neurol 1984; 41: 1248–54.CrossRefGoogle ScholarPubMed
15Koudstaal, PJ, Van Gijn, J, Staal, A, Duivenvoorden, HJ, Gerritsma, JGM, Kraaijeveld, CL. Diagnosis of transient ischaemic attacks: improvement of interobserver agreement by a check-list in ordinary language. Stroke 1986; 17: 723–28.CrossRefGoogle ScholarPubMed
16Whisnant, JP.Classification of cerebrovascular diseases III. Stroke 1990; 21: 637–76.Google Scholar
17Warlow, CP, Morris, PJ ed. Transient ischaemic attack. New York: Marcel Dekker, 1982: ix–xii.Google Scholar
18Sisk, C, Ziegler, DK, Zileli, T.Discrepancies in recorded results from duplicate neurological history and examination in patients studied for prognosis in cerebrovascular disease. Stroke 1970; 1: 14–18.CrossRefGoogle ScholarPubMed
19Shinar, D, Gross, CR, Mohr, JP et al. Interobserver variability in the assessment of neurologic history and examination in the Stroke Data Bank. Arch Neurol 1985; 42: 557–65.Google Scholar
20Kessler, C, Freyberger, HJ, Dittmann, V, Ringelstein, EB.Interrater reliability in the assessment of neurovas-cular diseases. Cerebrovasc Dis 1991; 1: 43–48.CrossRefGoogle Scholar
21Sandercock, PAG.Recent developments in the diagnosis and management of patients with transient ischaemic attacks and minor ischaemic stroke. Q J Med 1991; 286: 101–12.Google Scholar
22Hankey, GJ, Warlow, CP.The role of imaging in the management of cerebral and ocular ischaemia. Neuroradiology 1991; 33: 381–90.CrossRefGoogle ScholarPubMed
23Bogousslavsky, J, Regli, F.Cerebral infarction with transient signs (CITS): do TIAs correspond to small deep infarcts in internal carotid artery occlusion? Stroke 1984; 15: 536–39.CrossRefGoogle ScholarPubMed
24Bryan, RN, Levy, LM, Whitlow, WD, Killian, JM, Preziosi, TJ, Rosario, JA.Diagnosis of acute cerebral infarction: comparison of CT and MR imaging. AJR 1991; 157: 585–94.Google Scholar
25Hommel, M, Besson, G, Le Bas, JF et al. Prospective study of lacunar infarction using magnetic resonance imaging. Stroke 1990; 21: 546–54.Google Scholar
26Dennis, MS, Bamford, JM, Sandercock, PAG, Molyneux, A, Warlow, CP.Computerised tomography in patients with transient ischaemic attacks: when is a transient ischaemic attack not a transient ischaemic attack but a stroke? J Neurol 1990: 237: 257–61.CrossRefGoogle Scholar
27Allen, CMC.Clinical diagnosis of the acute stroke syndrome. Q J Med 1983; 208: 515–23.Google Scholar
28Sandercock, PAG, Allen, CMC, Corston, RN, Harrison, MJG, Warlow, CP.Clinical diagnosis of intracranial haemorrhage using Guy's Hospital score. Br Med J 1985; 291: 1675–77.CrossRefGoogle ScholarPubMed
29Poungvarin, N, Viriyavejakul, A, Komontri, C.Siriraj stroke score and validation study to distinguish supratentorial intracerebral haemorrhage from infarction. Br Med J 1991; 302: 1565–67.CrossRefGoogle ScholarPubMed
30Dennis, MS, Bamford, JM, Molyneux, AJ, Warlow, CP.Rapid resolution of signs of primary intracerebral haemorrhage in computed tomograms of the brain. Br Med J 1987; 295: 379–81.CrossRefGoogle ScholarPubMed
31Dooms, GC, Uske, A, Brant-Zawadski, M.Spin-echo MR imaging of intracranial haemorrhage. Neuroradiology 1986; 28: 132–38.CrossRefGoogle Scholar
32Ramadan, NM, Deveshwar, R, Levine, SR.Magnetic resonance and clinical cerebrovascular disease. An update. Stroke 1989; 20: 1279–83.CrossRefGoogle ScholarPubMed
33Ladurner, G, Sager, WD, Hoefler, H. et al. Computerised tomography (CT) correlated with anatomic pathology in stroke. In: Meyer, JS, Lechner, H, Reivich, M eds. Cerebral vascular disease 2. Amsterdam: Excerpta Medica, 1979: 75–80.Google Scholar
34Moseley, I ed. Acute disturbances of cerebral function: stroke and cerebrovascular disease. In: Magnetic resonance imaging in diseases of the nervous system. An introduction. Oxford: Blackwell, 1988: 20–34.Google Scholar
35Bamford, JM, Warlow, CP.Evolution and testing of the lacunar hypothesis. Stroke 1988; 19: 1074–82.CrossRefGoogle ScholarPubMed
36Waterston, JA, Brown, MM, Butler, P, Swash, M.Small deep cerebral infarcts associated with occlusive internal carotid artery disease. Arch Neurol 1990; 47: 953–57.CrossRefGoogle ScholarPubMed
37Hankey, GJ, Warlow, CP.Lacunar transient ischaemic attacks: a clinically useful concept? Lancet 1991; 337: 335–38.CrossRefGoogle ScholarPubMed
38Bladin, PF, Berkovic, SF.Striatocapsular infarction: large infarcts in the lenticulostriate arterial territory. Neurology 1984; 34: 1423–30.CrossRefGoogle ScholarPubMed
39Hankey, GJ.Khangure, MS, Stewart-Wynne, EG.Detection of basilar artery thrombosis by computed tomography Clin Radial 1988; 39: 140–43.CrossRefGoogle ScholarPubMed
40Wodarz, R. Watershed infarctions and computed tomography. A topographical study in cases with stenosis or occlusion of the carotid artery. Neuroradiology 1980; 19: 245–48.CrossRefGoogle ScholarPubMed
41Angeloni, U, Bozzao, L, Fantozzi, L, Bastianello, S, Kusher, M, Fieschi, C.Internal border-zone infarction following acute middle cerebral artery occlusion. Neurology 1990; 40: 1196–98.CrossRefGoogle Scholar
42Virapongse, C, Cazenave, C, Quisling, R, Sarwar, M, Hunter, S.The empty delta sign: frequency and significance in 76 cases of dural sinus thrombosis. Radiology 1987; 162: 779–85.CrossRefGoogle ScholarPubMed
43Macchi, PJ, Grossman, JM, Gomon, JM, Goldberg, HI, Zimmerman, RA, Bilanuik, LT.High field MR imaging of cerebral venous thrombosis. J Comput Assist Tomog 1986; 10: 10–15.CrossRefGoogle Scholar
44Brooks, DJ.PET: its clinical role in neurology. J Neurol Neurosurg Psychiatry 1991; 54: 1–5.CrossRefGoogle ScholarPubMed
45Neirinckx, 1987, Hayman, LA, Taber, KH, Jhingran, SG, Killian, JM, Carroll, RG.Cerebral infarction: diagnosis and assessment of prognosis using 123 IMP-SPECTand CT. AJNR 1989; 10: 557–62.Google Scholar
46Raynaud, C, Rancurel, G, Tzourio, N et al. SPECT analysis of recent cerebral infarction. Stroke 1989; 20: 192–204.Google Scholar
47Hughes, RL, Yonas, H, Gur, D, Latchaw, R.Cerebral blood flow determination within the first 8 hours of cerebral infarction using stable xenon-enhanced computed tomography. Stroke 1989; 20: 754–60.CrossRefGoogle ScholarPubMed
48Naylor, AR, Merrick, MV, Slattery, JM, Notghi, A, Fennington, CM, Miller, JD.Parametric imaging of cerebral vascular reserve. II. Reproducibility, response to CO2 and comparison with middle cerebral artery velocities. Eur J Nucl Med 1991; 18: 259–64.Google Scholar
49Wechsler, LR.Ulceration and carotid artery disease. Stroke 1988; 19: 650–53.CrossRefGoogle ScholarPubMed
50Estol, C, Claassen, D, Hirsch, W, Wechsler, L, Moossy, J.Correlative angiographic and pathologic findings in the diagnosis of ulcerated plaques in the carotid artery. Arch Neurol 1991; 48: 692–94.CrossRefGoogle ScholarPubMed
51North American Symptomatic Carotid Endarterectomy Trial (NASCET). Beneficial effect of carotid endarterectomy in symptomatic patients with high-grade carotid stenosis. N Engl J Med 1991; 325: 445–53.CrossRefGoogle Scholar
52European Carotid Surgery Trialists' Collaborative Group. MRC European Carotid Surgery Trial: interim results for symptomatic patients with severe (70–99%) or with mild (0–29%) carotid stenosis. Lancet 1991; 337: 1235–43.CrossRefGoogle Scholar
53Hankey, GJ, Warlow, CP.Symptomatic carotid ischaemic events: safest and most cost-effective way of selecting patients for angiography, before carotid endarterectomy. Br Med J 1990; 300: 1485–91.CrossRefGoogle ScholarPubMed
54Castaldo, JE, Nicholas, GG, Gee, W, Reed, JF.Duplex ultrasound and ocular pneumoplethysmography concordance in detecting severe carotid stenosis. Arch Neurol 1989; 46: 518–22.CrossRefGoogle ScholarPubMed
55Humphrey, P, Sandercock, P, Slattery, J.A simple method to improve the accuracy of non-invasive ultrasound in selecting TIA patients for cerebral angiography. J Neurol Neurosurg Psychiatry 1990; 53: 966–71.CrossRefGoogle ScholarPubMed
56Lewis, BD, James, EM, Welch, TJ.Current applications of duplex and color Doppler ultrasound imaging: carotid and peripheral vascular system. Mayo Clin Proc 1989; 64: 1147–57.CrossRefGoogle ScholarPubMed
57Carroll, BA.Carotid sonography. Radiology 1991; 178: 303–13.CrossRefGoogle ScholarPubMed
58Poli, A, Tremoli, E, Colombo, A, Sirtori, M, Pignoli, P, Paoletti, R.Ultrasonographic measurement of common carotid arterial wall thickness in hypercholesterolaemic patients. Atherosclerosis 1988; 70: 253–61.CrossRefGoogle Scholar
59Weinberger, J, Ramos, L, Ambrose, JA, Fuster, V.Morphologic and dynamic changes of atherosclerotic plaque at the carotid artery bifurcation: sequential imaging by real time B-mode ultrasonography. J Am Coll Cardiol 1988; 12: 1515–21.CrossRefGoogle ScholarPubMed
60Mitchell, DG.Colour Doppler imaging: principles, limitations and artifacts. Radiology 1990; 177: 1–10.CrossRefGoogle ScholarPubMed
61Steinke, W, Kloetzch, C, Hennerici, M.Carotid artery disease assessed by colour Doppler flow imaging. Correlation with standard Doppler sonography and angiography. JR 1990; 154: 1061–68.Google ScholarPubMed
62Edelman, RR, Mattle, HP, Atkinson, DJ, Hoogewoud, HM.MR angiography. AJR 1990; 154: 937–46.CrossRefGoogle ScholarPubMed
63Caplan, LR, Wolpert, SM.Angiography in patients with occlusive cerebrovascular disease: views of a stroke neurologist and neuroradiologist. AJNR 1991; 12: 593–601.Google ScholarPubMed
64Hankey, GJ, Warlow, CP, Sellar, RJ.Cerebral angiographic risk in mild cerebrovascular disease. Stroke 1990; 21: 209–22.CrossRefGoogle ScholarPubMed
65Hankey, GJ, Warlow, CP, Molyneux, AJ.Complications of cerebral angiography for patients with mild carotid territory ischaemia being considered for carotid endarterectomy. J Neurol Neurosurg Psychiatry 1990; 53: 542–48.CrossRefGoogle ScholarPubMed
66Petty, GW, Wiebers, DO, Meissner, I.Transcranial Doppler ultrasonography: clinical applications in cerebrovascular disease. Mayo Clin Proc 1990; 65: 1350–64.CrossRefGoogle ScholarPubMed
67Popp, RL.Echocardiography. N Engl J Med 1990; 323: 101–109, 165–72.CrossRefGoogle ScholarPubMed
68Pop, G, Sutherland, GR, Koudstaal, PJ, Sit, TW, De Jong, G, Roelandt, JRTC.Transesophageal echocardiography in the detection of intracardiac embolic sources in patients with transient ischaemic attacks. Stroke 1990; 21: 560–65.CrossRefGoogle Scholar
69Love, BB, Struck, LK, Stanford, W, Biller, J, Kerber, R, Marcus, M.Comparison of two-dimensional echocardiography and ultrafast cardiac computed tomography for evaluating intracardiac thrombi in cerebral ischaemia. Stroke 1990; 21: 1033–38.CrossRefGoogle Scholar
70Seward, JB, Khandheria, BK, Tajik, AJ.Wide-field transoesophageal echocardiographic tomography: feasibility study. Mayo Clin Proc 1990; 65: 31–37.CrossRefGoogle ScholarPubMed
71Rose, G.Strategy for prevention: lessons from cardiovascular disease. Br Med J 1981; 282: 1847–50.CrossRefGoogle ScholarPubMed
72Rose, G, Day, S.The population mean predicts the number of deviant individuals. Br Med J 1990; 301: 1031–34.CrossRefGoogle ScholarPubMed
73Schoenberg, BS, Schoenberg, DG, Pritchard, DA, Lilienfeld, AM, Whisnant, JP.Proportion of ischaemic stroke attributable to various forms of cardiovascular disease, diabetes mellitus and transient ischaemic attacks. J Neurol 1985; 232: (suppl): 98.Google Scholar
74Sandercock, PAG, Warlow, CP, Jones, LN, Starkey, IR.Predisposing factors for cerebral infarction: the Oxfordshire Community Stroke Project. Br Med J 1989; 298: 75–80.CrossRefGoogle ScholarPubMed
75Shaper, AG, Phillips, AN, Pocock, SJ, Walker, M, Macfarlane, PW.Risk factors for stroke in middle aged British men. Br Med J 1991; 302: 1111–15.CrossRefGoogle ScholarPubMed
76Bonita, R, Scragg, R, Stewart, A, Jackson, R, Beaglehole, R.Cigarette smoking and risk of premature stroke in men and women. Br Med J 1986; 293: 6–8.CrossRefGoogle ScholarPubMed
77Colditz, GA, Bonita, R, Stampfer, MJ et al. Cigarette smoking and risk of stroke in middle-aged women. N Engl J Med 1988; 318: 937–41.Google Scholar
78Wolf, PA, D'agostino, RB, Kannel, WB, Bonita, R, Belanger, AJ.Cigarette smoking as a risk factor for stroke: the Framingham Study. JAMA 1988; 259: 1025–29.CrossRefGoogle ScholarPubMed
79Shinton, R, Beevers, G.Meta-analysis of relation between cigarette smoking and stroke. Br Med J 1989; 298: 789–94.CrossRefGoogle ScholarPubMed
80Donnan, GA, McNeil, JJ, Adena, MA, Doyle, AE, O'malley, HMO, Neill, GC.Smoking as a risk factor for cerebral ischaemia. Lancet 1989; ii: 643–47.CrossRefGoogle Scholar
81Macmahon, S, Peto, R, Cutler, J et al. Blood pressure, stroke, and coronary heart disease. Part 1, prolonged differences in blood pressure: prospective observational studies corrected for the regression dilution bias. Lancet 1990; 335: 765–74.Google Scholar
82Collins, R, Peto, R, Macmahon, S et al. Blood pressure, stroke and coronary heart disease. Part 2, short-term reductions in blood pressure: overview of randomised drug trials in their epidemiological context. Lancet 1990; 335: 827–38.Google Scholar
83Peto, R, Yusuf, S, Collins, R.Cholesterol lowering trial results in their epidemiological context [Abstract]. Circulation 1985; 72: (suppl III): III–451.Google Scholar
84Antiplatelet Trialists' Collaboration. Secondary prevention of vascular disease by prolonged antiplatelet treatment. Br Med J 1988; 296: 320–31.CrossRefGoogle Scholar
85Warlow, CP.Ticlopidine, a new antithrombotic drug: but is it better than aspirin for long term use? J Neurol Neurosurg Psychiatry 1990; 53: 185–87.CrossRefGoogle Scholar
86Petersen, P, Boysen, G, Godfredsen, J, Andersen, E, Andersen, B.Placebo-controlled randomised trial of warfarin and aspirin for prevention of thromboembolic complications in chromic atrial fibrillation. Lancet 1988; i: 175–79.Google Scholar
87The Stroke Prevention in Atrial Fibrillation Study Group. Preliminary report of the Stroke Prevention in Atrial Fibrillation Study. N Engl J Med 1990; 322: 863–68.CrossRefGoogle Scholar
88The Stroke Prevention in Atrial Fibrillation Study Group. The Stroke Prevention in Atrial Fibrillation Study: final results. Circulation 1991; 84: 527–39.CrossRefGoogle Scholar
89The Boston Area Anticoagulation Trial for Atrial Fibrillation Investigators. The effect of low-dose warfarin on the risk of stroke in patients with nonrheumatic atrial fibrillation. N Engl J Med 1990; 323: 1505–11.CrossRefGoogle Scholar
90Albers, GW, Sherman, DG, Cress, DR, Paulseth, JE, Petersen, P.Stroke prevention in nonvalvular atrial fibrillation: a review of prospective randomised trials. Ann Neurol 1991; 30: 511–18.CrossRefGoogle Scholar
91Baker, RN, Broward, JA, Fang, HC et al. Anticoagulant therapy in cerebral infarction. Neurology 1962; 12: 823–35.Google Scholar
92Cerebral Embolism Study Group. Immediate anticoagulation of embolic stroke. A randomised trial. Stroke 1983; 14: 668–76.CrossRefGoogle Scholar
93Hankey, GJ, Slattery, JM, Warlow, CP.Transient ischaemic attacks. Which patients are at high (and low) risk of serious vascular events? J Neurol Neurosurg Psychiatry 1992 (in press).CrossRefGoogle ScholarPubMed
94Brown, MM, Butler, P, Gibbs, J.Swash, M, Waterston, J.Feasibility of percutaneous transluminal angioplasty for carotid artery stenosis. J Neurol Neurosurg Psychiatry 1990; 53: 238–43.CrossRefGoogle ScholarPubMed
95Duke, RJ, Bloch, RF, Turpie, AGG, Trebilcock, R, Bayer, N.Intravenous heparin for the prevention of stroke progression in acute partial stable stroke: a randomised controlled trial. Ann Intern Med 1986; 105: 825–28.CrossRefGoogle Scholar
96Gray, CS, French, JM, Venables, GS, Cartlidge, NEF, James, OFW, Bates, D.A randomised double-blind controlled trial of naftidrofuryl in acute stroke. Age Ageing 1990; 19: 356–63.CrossRefGoogle ScholarPubMed
97Matthews, WB, Oxbury, JM, Grainger, KMR, Greenhall, RCD.A blind controlled trial of dextran 40 in the treatment of ischaemic stroke. Brain 1976; 99: 193–206.CrossRefGoogle ScholarPubMed
98Italian Acute Stroke Study Group. Haemodilution in acute stroke: results of the Italian Haemodilution Trial. Lancet 1988; i: 318–21.Google Scholar
99Asplund, K.Randomised clinical trials of haemodilution in acute ischaemic stroke. Acta Neurol Scand 1989; 127 (suppl): 22–30.CrossRefGoogle Scholar
100Mulley, G, Wilcox, RG, Mitchell, JRA.Dexamethasone in acute stroke. Br Med J 1918; 2: 994–96.CrossRefGoogle Scholar
101Bayer, AJ, Pathy, MSJ, Newcombe, R.Double-blind randomised trial of intravenous glycerol in acute stroke. Lancet 1987; i: 405–408.CrossRefGoogle Scholar
102Barer, DH, Cruickshank, JM, Ebrahim, SB, Mitchell, JRA.Low dose B blockade in acute stroke (‘BEST’ trial): an evaluation. Br Med J 1988; 296: 737–41.CrossRefGoogle Scholar
103Trust Study Group. Randomised, double-blind, placebo-controlled trial of nimodipine in acute stroke. Lancet 1990; 336: 1205–1209.CrossRefGoogle Scholar
104Argentine, C, Sacchetti, ML, Toni, D et al. GM1 ganglioside therapy in acute ischaemic stroke. Stroke 1989; 20: 1143–49.Google Scholar
105Czlonkowska, A, Mendel, T, Baranska-Gieruszcak, M.Naloxone in acute ischaemic stroke: double blind controlled study. J Neurol 1990; 237: 153.Google Scholar
106Olinger, CP, Adams, HP, Brott, TG et al. High dose intravenous naloxone for the treatment of acute ischaemic stroke. Stroke 1990; 21: 721–25.Google ScholarPubMed
107Sandercock, PAG.Important new treatments for acute ischaemic stroke. Br Med J 1987; 295: 1225–26.CrossRefGoogle ScholarPubMed
108ISIS-2 (Second International Study of Infarct Survival) Collaborative Group. Randomised trial of intravenous streptokinase, oral aspirin, both, or neither among 17, 187 cases of suspected acute myocardial infarction: ISIS-2. Lancet 1988; ii: 349–60.Google Scholar
109Del Zoppo, GJ.Thrombolytic therapy in cerebrovascular disease. Stroke 1988; 19: 1174–79.CrossRefGoogle ScholarPubMed
110Pessin, MS, Del Zoppo, GJ, Estol, CJ.Thrombolytic agents in the treatment of stroke. Clin Pharmacol 1990; 13: 271–89.Google ScholarPubMed
111Antiplatelet Trialists Collaboration. Proceedings of the second main meeting, March 1990. In press.Google Scholar
112Nakagomi, T, Sasaki, T, Kirino, T, Tamura, A, Noguchi, M, Saito, I, Takakura, K.Effect of cyclooxygenase and lipoxygenase inhibitors on delayed neuronal death in the gerbil hippocampus. Stroke 1989; 20: 925–29.CrossRefGoogle ScholarPubMed
113ISIS-3 collaborative group. A randomised trial of streptokinase, r-tPA and APSAC with and without twice daily and subcutaneous heparin in 46, 092 patients with suspected acute myocardial infarction. In press.Google Scholar
114The SCATI group. Randomised controlled trial of subcutaneous calcium-heparin in acute myocardial infarction. Lancet 1989; ii: 182–86.Google Scholar
115Turpie, AGG, Robinson, JG, Doyle, DJ et al. Comparison of high dose with low dose subcutaneous heparin to prevent left ventricular mural thrombosis in patients with acute transmural anterior myocardial infarction. N Engl J Med 1989; 320: 352–57.Google Scholar
116Sandercock, PAG, Van Den Belt, AGM, Lindley, RI, Slattery, J.Antithrombotic therapy in acute ischaemic stroke: an overview of the completed randomised trials. (Unpublished observations.)Google Scholar
117Collins, R, Scrimgeour, A, Yusuf, S, Peto, R.Reduction in fatal pulmonary embolism and venous thrombosis by perioperative administration of subcutaneous heparin. N Engl J Med 1988; 318: 1162–73.CrossRefGoogle ScholarPubMed
118Macmahon, S, Collins, R, Knight, C et al. Reduction in major morbidity and mortality by heparin in acute myocardial infarction. Circulation 1988; 78: 11–98.Google Scholar
119Wong, MCW, Haley, EC Jr.Calcium antagonists: stroke therapy coming of age. Stroke 1990; 21: 494–501.CrossRefGoogle ScholarPubMed
120Albers, GW, Goldberg, MP, Choi, DW.N-Methyl-D-aspartate receptor antagonists: ready for clinical trial in brain ischaemia? Ann Neurol 1989; 25: 398–403.CrossRefGoogle Scholar
121Scatton, B, Carter, C, Benavides, J, Giroux, C.N-methyl-D-aspartate receptor antagonists: a novel therapeutic perspective for the treatment of ischaemic brain injury. Cerebrovasc Dis 1991; 1: 121–35.CrossRefGoogle Scholar
122Schmidley, JW.Free radicals in central nervous system ischaemia. Stroke 1990; 21: 1086–90.CrossRefGoogle Scholar
123Goldstein, LB, Davis, JN.Restorative neurology. Drugs and recovery following stroke. Stroke 1990; 21: 1636–39.CrossRefGoogle ScholarPubMed
124Pickard, JD, Murray, GD, Illingworth, R et al. Effect of oral nimodipine on cerebral infarction and outcome after subarachnoid haemorrhage: British aneurysm nimodipine trial. Br Med J 1989; 298: 636–42.Google Scholar