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The noncognitive features of dementia

Published online by Cambridge University Press:  17 November 2008

NHP Allen  and
Alistair Burns
NHP Allen*
Affiliation:
The University of Manchester, Manchester, UK
Alistair Burns
Affiliation:
The University of Manchester, Manchester, UK
*
H Allen, The University of Manchester, School of Psychiatry and Behavioural Sciences, Withington Hospital, West Didsbury, Manchester M20 8LR, UK.
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Abstract

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Type
Psychiatry of old age
Information
Reviews in Clinical Gerontology , Volume 5 , Issue 1 , February 1995 , pp. 57 - 75
Copyright
Copyright © Cambridge University Press 1995

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References

1 Alzheimer, A, Über eine Eigenartige Erkrankung der Hirnrinde. Allgemeine Zeitschrift für Psychiatrie and Psychisch-Gerichtlich Medicin 1907; 64: 146–48.Google Scholar
2 Kiloh, LG. Pseudo-dementia. Acta Psychiatr Scand 1961; 37: 336–51.CrossRefGoogle ScholarPubMed
3 Rabins, PV, Merchant, A, Nestadt, G. Criteria for diagnosing reversible dementia caused by depression: validation by 2-year follow-up. Br J Psychiatry 1984; 144: 488–92.CrossRefGoogle ScholarPubMed
4 Emery, VO, Oxman, TE. Update on the dementia spectrum of depression. Am J Psychiatry 1992; 149: 305–17.Google ScholarPubMed
5 Nott, PN, Fleminger, JJ. Presenile dementia: the difficulties of early diagnosis. Acta Psychiatr Scand 1975; 51: 210–17.CrossRefGoogle ScholarPubMed
6 Lauter, H, Dame, S. Depressive disorders and dementia: the clinical view. Acta Psychiatr Scand Suppl 1991;366: 40–46.CrossRefGoogle ScholarPubMed
7 Burke, WJ, Rubin, EH, Morris, JC, Berg, L. Symptoms of ‘depression’ in dementia of the Alzheimer type. Alzheimer Dis Assoc Disord 1988; 2(4): 356–62.CrossRefGoogle ScholarPubMed
8 Merriam, AE, Aronson, MK, Gastopn, P, Wey, Su-L, Katz, I. The psychiatric symptoms of Alzheimer's disease. J Am Geriatr Soc 1988; 36: 7–12.Google Scholar
9 Cummings, JL, Miller, B, Hill, MA, Neshkes, R. Neuropsychiatric aspects of multi-infarct dementia and dementia of the Alzheimer type. Arch Neurol 1987; 44: 389–93.CrossRefGoogle ScholarPubMed
10 American Psychiatric Association. Diagnostic and statistical manual of mental disorders, third edition. Washington DC: American Psychiatric Association, 1980.Google Scholar
11 Troisi, A, Pasini, A, Gori, G et al. Assessment of depression in Alzheimer's disease: symptoms, syndrome, and computed tomography findings. Dementia 1993; 4(2): 87–93.Google ScholarPubMed
12 Hamilton, M. A rating scale for depression. J Neurol Neurosurg Psychiatry 1960; 23: 56–62.CrossRefGoogle ScholarPubMed
13 Knesevich, JW, Martin, RL, Berg, L, Danziger, W. Preliminary report on affective symptoms in the early stages of senile dementia of the Alzheimer type. Am J Psychiatry 1983; 140: 233–35.Google Scholar
14 Zung, WWK. A self-rating depression scale. Arch Gen Psychiatry 1965; 12: 63–70.CrossRefGoogle ScholarPubMed
15 Blessed, G, Tomlinson, BE, Roth, R. The association between quantitative measures of dementia and senile change in the cerebral gray matter of elderly subjects. Br J Psychiatry 1968; 114: 797–811.Google Scholar
16 Breen, AR, Larson, EB, Reifler, BV, Vitaliano, PP, Lawrence, GL. Cognitive performance and functional competence in co-existing dementia and depression. J Am Geriatr Soc 1984; 32: 132–37.CrossRefGoogle Scholar
17 Reifler, BV, Larson, EB, Teri, L, Poulsen, M. Dementia of the Alzheimer's type and depression. J Am Geriatr Soc 1986; 34: 855–59.Google Scholar
18 Folstein, MF, Folstein, S, McHugh, P. Mini-mental state. J Psychiatr Res 1975; 12: 189–98.CrossRefGoogle ScholarPubMed
19 Lazarus, L, Newton, N, Cohler, B, Lesser, J, Schweon, C. Frequency and presentation of depressive symptoms in patients with primary degenerative dementia. Am J Psychiatry 1987; 144: 41–45.Google Scholar
20 Feighner, JP, Robins, E, Guze, SB, Woodruff, RA Jr, Winokur, G, Munoz, R. Diagnostic criteria for use in psychiatric research. Arch Gen Psychiatry 1972; 26: 57–63.CrossRefGoogle ScholarPubMed
21 McKhann, G, Drachman, DA, Folstein, MF, Katzman, R, Price, D, Stalan, EM. Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services task force on Alzheimer's disease. Neurology 1984; 34: 939–44.CrossRefGoogle ScholarPubMed
22 Krishnan, KRR, Heyman, A, Ritchie, JC, Utley, CM, Dawson, DV, Rogers, H. Depression in early onset Alzheimer's disease: clinical and neuroendocrine correlates. Biol Psych 1988; 24: 937–40.CrossRefGoogle ScholarPubMed
23 Woodruff, RA Jr, Goodwin, DW, Guze, SB eds. Psychiatric diagnosis. New York: Oxford University Press, 1974.Google Scholar
24 Kumar, A, Koss, E, Metzler, D, Moore, A, Freidland, RP. Behavioral symptomatology in dementia of the Alzheimer type. Alzheimer Dis Assoc Disord 1988; 2(4): 363–65.CrossRefGoogle ScholarPubMed
25 Spitzer, RL, Endicott, J. The schedule for affective disorders (SDAS-C). Arch Gen Psychiatry 1971; 24: 540–47.CrossRefGoogle Scholar
26 Zubenko, GS, Moossy, J. Major depression in primary dementia. Arch Neurol 1988; 45: 1182–86.CrossRefGoogle ScholarPubMed
27 Mackenzie, TB, Robiner, WN, Knopman, DS. Differences between patient and family assessments of depression in Alzheimer's disease. Am J Psychiatry 1989; 146: 1174–78.Google ScholarPubMed
28 Reisberg, B, Franssen, E, Sclan, SG, Kluger, A, Ferris, SH. Stage specific indicence of potentially remediable behavioural symptoms in aging and Alzheimer disease. A study of 120 patients using the BEHAVE-AD. Bull Clin Neurosci 1989; 54: 95–112.Google Scholar
29 Reisberg, B, Borenstein, J, Salob, SP, Ferris, SH, Franssen, E, Georgotas, A. Behavioural symptoms in Alzheimer's disease: phenomenology and treatment. J Clin Psychiatry 1987; 48(5) suppl: 9–15.Google Scholar
30 American Psychiatric Association. Diagnostic and statistical manual of mental disorders, third (revised) edition. Washington DC: American Psychiatric Association, 1987.Google Scholar
31 Rovner, BW, Broadhead, J, Spencer, M, Carson, K, Folstein, MF. Depression and Alzheimer's disease. Am J Psychiatry 1989; 146: 350–53.Google ScholarPubMed
32 Wing, JK, Cooper, JE, Sartorius, N eds. The measurement and classification of psychiatric symptoms: an instruction manual for the PSE and CATEGO programs. New York: Cambridge University Press, 1974.Google Scholar
33 Burns, AB, Jacoby, R, Levy, R. Psychiatric phenomena in Alzheimer's disease. III Disorders of mood. Br J Psychiatry 1990, 157: 81–86.Google Scholar
34 Copeland, J, Kelleher, M, Kellett, J et al. The Geriatric Mental State Schedule: development and reliability. Psychol Med 1976; 6: 439–49.CrossRefGoogle ScholarPubMed
35 Cooper, JK, Mungas, D, Weiler, PG. Relation of cognitive status and abnormal behaviours in Alzheimer's disase. J Am Geriatr Soc 1990; 38: 867–70.CrossRefGoogle Scholar
36 Lopez, OL, Boller, F, Becker, JT, Miller, M, Reynolds, CF III. Alzheimer's disease and depression: neuropsychological impairment and progression of the illness. Am J Psychiatry 1990; 147: 855–60.Google ScholarPubMed
37 Patterson, MB, Schnell, AH, Martin, RL, Mendez, MF, Smyth, KA, Whitehouse, PJ. Assessment of behavioral and affective symptoms in Alzheimer's disease. J Geriatr Psychiatry Neurol 1990; 3: 21–30.CrossRefGoogle ScholarPubMed
38 Rosen, J, Zubenko, GS. Emergence of psychosis and depression in the longitudinal evaluation of Alzheimer's disease. Biol Psych 1991; 29: 224–32.Google Scholar
39 Devanand, DP, Miller, L, Richards, M et al. The Columbia University scale for psychopathology in Alzheimer's disease. Arch Neurol 1992; 49: 371–76.CrossRefGoogle ScholarPubMed
40 Mayeux, R, Stern, Y, Rosen, J, Leventhal, J. Depression, intellectual impairment and Parkinson's disease. Neurology 1981; 31: 645–50.CrossRefGoogle Scholar
41 Zubenko, GS, Rosen, J, Sweet, RA, Mulsant, BH, Rifai, AH. Impact of psychiatric hospitalization on behavioral complications of Alzheimer's disease. Am J Psychiatry 1992; 149: 1484–91.Google ScholarPubMed
42 Corey-Bloom, J, Galasko, D, Hofstetter, R, Jackson, JE, Thal, LJ. Clinical features distinguishing large cohorts with possible AD, probable AD, and mixed dementia. J Am Geriatr Soc 1993; 41: 31–37.CrossRefGoogle ScholarPubMed
43 Bucht, G, Adolfsson, R. The comprehensive psychopathological rating scale in patients with dementia of the Alzheimer type and multi-infarct dementia. Acta Psychiatr Scand 1983; 68: 263–70.Google Scholar
44 Åsberg, M, Perris, CP, Schalling, D, Sedvall, G. The CPDS – development and applications of a psychiatric rating scale. Acta Psychiatr Scand Suppl 1978; 217.Google Scholar
45 Reding, M, Haycox, J, Blass, J. Depression in patients referred to a dementia clinic. Arch Neurol 1985; 42: 894–96.CrossRefGoogle ScholarPubMed
46 Greenwald, BS, Kramer-Ginsberg, E, Marin, DB et al. Dementia with coexistent major depression. Am J Psychiatry 1989; 146: 1472–78.Google Scholar
47 Cohen, D, Eisdorfer, C, Gorelick, P et al. Psychopathology associated with Alzheimer's disease and related disorders. J Gerontol 1993; 48(6): M255–60.Google Scholar
48 Sultzer, DL, Levin, HS, Mahler, ME, High, WM, Cummings, JL. A comparison of psychiatric symptoms in vascular dementia and Alzheimer's disease. Am J Psychiatry 1993; 150: 1806–1812.Google ScholarPubMed
49 Levin, HS, High, WM, Goethe, KE et al. The neurobehavioural rating scale: assessment of the behavioural sequelae of head injury by the clinician. J Neurol Neurosurg Psychiatry 1987; 50: 183–93.CrossRefGoogle ScholarPubMed
50 Blazer, DG. Affective disorders in late life. In: Busse, EW, Blazer, DG eds. Geriatric psychiatry. Washington DC: American Psychiatric Press, 1989.Google Scholar
51 Perry, RH, Irving, D, Blessed, G, Perry, EK, Fairburn, AF. Clinically and pathologically distinct form of dementia in the elderly. Lancet 1989; 1: 168.Google Scholar
52 McKeith, IG, Perry, RH, Fairburn, AF, Jabeen, S, Perry, EK. Operational criteria for senile dementia of Lewy body type (SDLT). Psychol Med 1992; 22: 911–22.Google Scholar
53 Jung, R, Solomon, K. Psychiatric manifestations of Pick's disease. Int Psychogeriatr 1993; 5: 187.CrossRefGoogle ScholarPubMed
54 Berrios, GE. Presbyophrenia: the rise and fall of a concept. Psychol Med 1986; 16: 267–75.CrossRefGoogle ScholarPubMed
55 Berrios, GE. Presbyophrenia: clinical aspects. Br J Psychiatry 1985; 147: 76–79.CrossRefGoogle ScholarPubMed
56 Agbayewa, MO, Weir, J, Tuokko, H, Beattie, L. Depression in dementia: its impact on functional ability. Dementia 1991; 2: 212–17.Google Scholar
57 Reifler, BV, Larson, EB, Hanley, R. Coexistence of cognitive impairment and depression in geriatric outpatients. Am J Psychiatry 1982; 139: 623–26.Google ScholarPubMed
58 Fischer, P, Simanyi, M, Danielczyk, W. Depression in dementia of the Alzheimer type and in multi-infarct dementia. Am J Psychiatry 1990; 147: 1484–87.Google ScholarPubMed
59 Sultzer, DL, Lewin, HS, Mahler, ME, High, WM, Cummings, JL. Assessment of cognitive, psychiatric, and behavioural disturbances in patients with dementia: the neurobehavioural rating scale. J Am Geriatr Soc 1992; 40: 549–55.Google Scholar
60 Fitz, AG, Teri, L. Depression, cognition, and functional ability in patients with Alzheimer's disease. J Am Geriatr Soc 1994; 42: 186–91.CrossRefGoogle ScholarPubMed
61 Eisdorfer, C, Cohen, D, Paveza, GJ et al. An empirical evaluation of the Global Deterioration Scale for staging Alzheimer's disease. Am J Psychiatry 1992; 149: 190–94.Google ScholarPubMed
62 Mayeux, R, Stern, Y, Spanton, S. Heterogeneity in dementia of the Alzheimer type: evidence of subgroups. Neurology 1985; 35: 453–61.Google Scholar
63 Agbayewa, MO. Earlier psychiatric morbidity in patients with Alzheimer's disease. J Am Geriatr Soc 1986; 34: 561–64.CrossRefGoogle ScholarPubMed
64 Chui, HC, Teng, EL, Henderson, VW, Moy, AC. Clinical subtypes of dementia of the Alzheimer type. Neurology 1985; 35: 1544–49.CrossRefGoogle ScholarPubMed
65 Nyth, AL, Gottfries, CG, Blennow, K, Bråne, G, Wallin, A. Heterogeneity of the course of Alzheimer's disease: a differentiation of subgroups. Dementia 1991; 2: 18–24.Google Scholar
66 Burns, A, Levy, R. Clinical diversity of late onset Alzheimer's disase. (Maudsley Monographs, 34.) Oxford: Oxford University Press, 1992.Google Scholar
67 Förstl, H, Burns, A, Luthert, P, Cairns, N, Lantos, P, Levy, R. Clinical and neuropathological correlates of depression in Alzheimer's disease. Psychol Med 1992; 22: 877–84.CrossRefGoogle ScholarPubMed
68 Zweig, RM, Ross, CA, Hedreen, JC et al. The neuropathology of aminergic nuclei in Alzheimer's disease. Ann Neurol 1988; 24: 233–42.Google Scholar
69 Zubenko, GS, Moossy, J, Kopp, U. Neurochemical correlates of major depression in primary dementia. Arch Neurol 1990; 47: 209–14.CrossRefGoogle ScholarPubMed
70 Liston, EH, Jarvik, LF, Gerson, S. Depression in Alzheimer's disease: an overview of adrenergic and cholinergic mechanisms. Compr Psychiatry 1987; 28: 444–57.CrossRefGoogle ScholarPubMed
71 Starkstein, SE, Robinson, RG, Price, TR. Comparison of patients with and without poststroke major depression matched for size and location of lesion. Arch Gen Psychiatry 1987; 45: 247–52.CrossRefGoogle Scholar
72 Starkstein, SE, Robinson, RG. Affective disorders and cerebrovascular disease. Br J Psychiatry 1989; 154: 170–82.CrossRefGoogle Scholar
73 Astrom, M, Adolfsson, R, Asplund, K. Major depression in stroke patients: a 3-year longitudinal study. Stroke 1993; 24: 976–82.CrossRefGoogle ScholarPubMed
74 Robinson, RG, Boston, JD, Starkstein, SE, Price, TR. Comparison of mania with depression following brain injury: causal factors. Am J Psychiatry 1988; 145: 172–78.Google Scholar
75 Pearlson, GD, Ross, CA, Lohr, WD, Rovner, BW, Chase, GA, Folstein, MF. Association between family history of affective disorder and the depressive syndrome of Alzheimer's disease. Am J Psychiatry 1990; 147: 452–56.Google ScholarPubMed
76 Morris, PLP, Robinson, RG, Raphael, B, Samuels, J, Molloy, P. The relationship between risk factors for affective disorder and poststroke depression in hospitalised stroke patients. Aust N Z J Psychiatry 1992; 26: 208–17.CrossRefGoogle ScholarPubMed
77 Reifler, BV, Teri, L, Raskind, MA et al. A double blind trial of a tricyclic antidepressant in Alzheimer's patients with and without depression. Am J Psychiatry 1989; 146: 45–49.Google ScholarPubMed
78 Lipsey, JR, Robinson, RG, Pearlson, GD, Rao, K, Price, TR. Nortriptyline treatment for poststroke depression: a double blind study. Lancet 1984; 1: 297–300.CrossRefGoogle ScholarPubMed
79 Reding, M, Orto, LA, Winter, SW, Fortuna, IM, Di Ponte, P, McDowell, FH. Antidepressant therapy after stroke: a double-blind trial. Arch Neurol 1986; 3: 763–65.Google Scholar
80 Jenike, MA. Monoamine oxidase inhibitors for treatment of depressed patients with primary dementia (Alzheimer's disease). Am J Psychiatry 1985; 142: 763–64.Google ScholarPubMed
81 Postma, JU, Vranesci, D. Moclobemide in the treatment of depression in demented geriatric patients. Acta Therapeutica 1985; 11: 1–4.Google Scholar
82 Nyth, AL, Gottfries, CG. The clinical efficacy of citalopram in treatment of emotional disturbances in dementia disorders. A Nordic multicentre study. Br J Psychiatry 1990; 157: 894–901.CrossRefGoogle ScholarPubMed
83 Nelson, JP, Rosenberg, DR. ECT treatment of demented elderly patients with major depression: a retrospective study of efficacy and safety. Convulsive Therapy 1991; 7: 157–65.Google ScholarPubMed
84 Rubin, EH, Drevets, WC, Burke, WJ. The nature of psychotic symptom in senile dementia of the Alzheimer type. J Geriatr Psychiatry Neurol 1988; 1: 16–20.CrossRefGoogle ScholarPubMed
85 Berg, L. Clinical dementia rating. Br J Psychiatry 1984; 145: 339.Google Scholar
86 Burns, A, Jacoby, R, Levy, R. Behavioral abnormalities and psychiatric symptoms in Alzheimer's disease: preliminary findings. Int Psychogeriatr 1990; 2(1): 25–36.CrossRefGoogle ScholarPubMed
87 Burns, AB, Jacoby, R, Levy, R. Psychiatric phenomena in Alzheimer's disease. IV Disorders of behaviour. Br J Psychiatry 1990; 157: 86–94.CrossRefGoogle ScholarPubMed
88 Burns, AB, Jacoby, R, Levy, R. Psychiatric phenomena in Alzheimer's disease. I: Disorders of thought content. Br J Psychiatry 1990; 157: 72–76.Google Scholar
89 Burns, AB, Jacoby, R, Levy, R. Psychiatric pehnomena in Alzheimer's disease. II: Disorders of perception. Br J Psychiatry 1990; 157: 76–81.CrossRefGoogle Scholar
90 Fish, F. Fish's clinical psychopathology, second edition (series editor: Hamilton, M.) Bristol: Wright, 1985.Google Scholar
91 Cummings, JL. Organic delusions: phenomenology, anatomical correlations and review. Br J Psychiatry 1985; 146: 184–97.Google Scholar
92 Cooper, JK, Mungas, D, Verma, M, Weiler, PG. Psychotic symptoms in Alzheimer's disease. Int J Geriatr Psychiatry 1991; 6: 721–26.CrossRefGoogle Scholar
93 Deutsch, LH, Bylsma, FW, Rovner, BW, Steele, C, Folstein, MF. Psychosis and physical aggression in probable Alzheimer's disease. Am J Psychiatry 1991; 148(9): 1159–63.Google ScholarPubMed
94 Gilley, DW, Whalen, ME, Wilson, RS, Bennett, DA. Hallucinations and associated factors in Alzheimer's disease. J Neuropsych Clin Neurosci 1991; 3(4): 371–76.Google ScholarPubMed
95 Khachaturian, ZS. Diagnosis of Alzheimer's disease. Arch Neurol 1985; 2: 1097–105.CrossRefGoogle Scholar
96 Lopez, OL, Becker, JT, Brenner, RP, Rosen, J, Bajulaiye, OI, Reynolds, CF III. Alzheimer's disease with delusions and hallucinations: neuropsychological and electroencephalographic correlates. Neurology 1991; 41: 906–12.CrossRefGoogle ScholarPubMed
97 Jeste, DV, Wragg, RE, Salmon, DP, Harris, MJ, Thal, LJ. Cognitive deficits of patients with Alzheimer's disease with and without delusions. Am J Psychiatry 1992;149(2): 184–89.Google ScholarPubMed
98 Mendez, MF, Martin, RJ, Smyth, KA, Whitehouse, PJ. Disturbances of person identification in Alzheimer's disease. A retrospective study. J Nerv Ment Dis 1992; 180: 94–96.Google Scholar
99 Förstl, H, Besthorn, C, Geiger-Kabisch, C, Sattel, H, Schreiter-Gasser, U. Psychotic features and the course of Alzheimer's disease: relationship to cognitive, electroencephalographic and computerized tomography findings. Acta Psychiatr Scand 1993; 87(6): 395–99.CrossRefGoogle ScholarPubMed
100 Roth, M, Tym, E, Mountjoy, C et al. CAMDEX: a standardized instrument for the diagnosis of mental disorder in the elderly with special reference to the early detection of dementia. Br J Psychiatry 1986; 149: 698–709.CrossRefGoogle Scholar
101 Flynn, FG, Cummings, JL, Gornbein, J. Delusions in dementia syndromes: investigation of behavioral and neuropsychological correlates. J Neuropsych Clin Neurosci 1991; 3: 364–70.Google Scholar
102 Ballard, CG, Chithiramohan, RN, Bannister, C, Handy, S, Todd, N. Paranoid features in the elderly with dementia. Int J Geriatr Psychiatry 1991; 6: 155–57.CrossRefGoogle Scholar
103 Binetti, G, Bianchetti, A, Padovani, A, Lenzi, G, De Leo, D, Trabucchi, M. Delusions in Alzheimer's disease and multi-infarct dementia. Acta Neurol Scand 1993; 88: 5–9.Google Scholar
104 Hansen, L, Salmon, D, Galasko, D et al. The Lewy body variant of Alzheimer's disease: a clinical and pathological entity. Neurology 1990; 40: 1–8.CrossRefGoogle Scholar
105 Perry, RH, Irving, D, Blessed, G, Fairburn, AF, Perry, EK. Senile dementia of the Lewy body type. A clinically and neuropathologically distinct form of Lewy body dementia in the elderly. J Neuro sci 1990; 95: 119–39.CrossRefGoogle ScholarPubMed
106 Burkhardt, CR, Filley, CM, Kleinschmidt-De Masters, BK, de la Monte, S, Norenberg, MD, Schneck, SA. Diffuse Lewy body disease and progressive dementia. Neurology 1988; 38: 1520–28.CrossRefGoogle ScholarPubMed
107 Byrne, EJ, Lennox, G, Lowe, J, Godwin-Austen, RB. Diffuse Lewy body disease: clinical features in 15 cases. J Neurol Neurosurg Psychiatry 1989; 52: 709–17.CrossRefGoogle ScholarPubMed
108 Ballinger, BR, Reid, AH, Heather, BB. Cluster analysis of symptoms in elderly demented patients. Br J Psychiatry 1982; 140: 257–62.Google Scholar
109 Berrios, GE, Brook, P. Delusions and the psychopathology of the elderly with dementia. Acta Psychiatr Scand 1985; 72: 296–301.CrossRefGoogle ScholarPubMed
110 Rubin, EH, Kinscherf, DA. Psychopathology of very mild dementia of the Alzheimer's type. Am J Psychiatry 1989; 146: 1017–21.Google Scholar
111 Rubin, EH, Kinscherf, DA, Morris, JC. Psychopathology in younger versus older persons with very mild and mild dementia of the Alzheimer type. Am J Psychiatry 1993; 150(4): 639–42.Google ScholarPubMed
112 Förstl, H, Burns, A, Luthert, P, Cairns, N, Levy, R. The Lewy body variant of Alzheimer's disease. Clinical and pathological findings. Br J Psychiatry 1993; 162: 385–92.Google Scholar
113 Förstl, H, Almeida, OP, Owen, AM, Burns, A, Howard, R. Psychiatric, neurological and medical aspects of misidentification syndromes: a review of 260cases. Psychol Med 1991; 21: 905–910.CrossRefGoogle Scholar
114 Drevets, WC, Rubin, EH. Psychotic symptoms and the longitudinal course of senile dementia of the Alzheimer's type. Biol Psychol 1989; 25: 39–48.CrossRefGoogle Scholar
115 Lachs, MS. Becker, M, Siegal, AP, Miller, RL, Tinetti, ME. Delusions and behavioral disturbances in cognitively impaired elderly persons. J Am Geriatr Soc 1992; 40(8): 768–73.CrossRefGoogle ScholarPubMed
116 Jacoby, R, Levy, R. Computed tomography in the elderly. 2. Senile dementia diagnosis and functional impairment. Br J Psychiatry 1980; 136: 256–69.Google Scholar
117 Teri, L, Larson, EB, Reifler, BV. Behavoural disturbance in dementia of the Alzheimer's type. J Am Geriatr Soc 1988; 36: 1–6.CrossRefGoogle Scholar
118 Rubin, EH. Psychopathology of senile dementia of the Alzheimer type. Adv Neurol 1990; 51: 53–59.Google ScholarPubMed
119 Förstl, H, Burns, A, Jacoby, R, Levy, R. Neuroanatomical correlates of clinical misidentification and misperception in senile dementia of the Alzheimer's type. J Clin Psychiatry 1991; 52: 268–71.Google Scholar
120 Kapur, N, Turner, A, King, C. Reduplicative paramnesia: possible anatomical and neuro-psychological mechanisms. J Neurol Neurosurg Psychiatry 1988; 51: 579–81.Google Scholar
121 Chen, Jenn-Y, Stern, Y, Sano, M, Mayeux, R. Cumulative risks of developing extrapyramidal signs, psychosis, or myoclonus in the course of Alzheimer's disease. Arch Neurol 1991; 48: 1141–43.Google Scholar
122 Schneider, LS, Pollock, VE, Lyness, SA. A metaanalysis of controlled trials of neuroleptic treatment in dementia. J Am Geriatr Soc 1990; 38: 553–63.Google Scholar
123 Zubenko, GS, Moossy, J, Martinez, AJ et al. Neuropathologic and neurochemical correlates of psychosis in primary dementia. Arch Neurol 1991; 48: 619–24.Google Scholar
124 Birkett, DP. The psychiatric differentiation of senility and arteriosclerosis. Br J Psychiatry 1972; 120: 321–25.Google Scholar
125 Rabins, PV, Mace, NL, Lucas, MJ. The impact of dementia on the family. JAMA 1982; 248: 333–35.CrossRefGoogle ScholarPubMed
126 Margo, JL, Robinson, JR, Corea, S. Referrals to a psychiatric service from old people's homes. Br J Psychiatry 1980; 136: 396–401.Google Scholar
127 Steele, C, Rovner, BW, Chase, GA, Folstein, MF. Psychiatric symptoms and nursing home placement of patients with Alzheimer's disease. Am J Psychiatry 1990; 147: 1049–51.Google ScholarPubMed
128 Everitt, DE, Fields, DR, Soumerai, SS, Avorn, J. Resident behavior and staff distress in the nursing home. J Am Geriatr Soc 1991; 39: 792–98.CrossRefGoogle ScholarPubMed
129 Cariaga, J, Burgio, L, Flynn, W, Martin, D. A controlled study of disruptive vocalizations among geriatric residents in nursing homes. J Am Geriatr Soc 1991; 39: 501–507.CrossRefGoogle ScholarPubMed
130 Shah, AK. Aggressive behavour among patients referred to a psychogeriatric service. Med Sci Law 1993; 33: 144–50.Google Scholar
131 Fairburn, CG, Hope, RA. Changes in behaviour in dementia: a neglected research area. Br J Psychiatry 1988; 152: 406–407.CrossRefGoogle ScholarPubMed
132 Hope, RA. Patel, V. Assessment of behavioural phenomena in dementia. In: Burns, A ed. Ageing and dementia: a methodological approach. London: Edward Arnold, 1993: 221–236.Google Scholar
133 Hope, RA, Fairburn, CG. The Present Behavioural Examination (PBE): the development of an interview to measure current behavioural abnormalities. Psychol Med 1992; 22: 223–30.CrossRefGoogle ScholarPubMed
134 Patel, V, Hope, RA. Aggressive behaviour in elderly psychiatric inpatients. Acta Psychiatr Scand 1992; 85: 131–35.Google Scholar
135 Malone, ML, Thompson, L, Goodwin, JS. Aggressive behaviors among the institutionalized elderly. J Am Geriatr Soc 1993; 41: 853–56.CrossRefGoogle ScholarPubMed
136 Tune, LE, Steele, C, Cooper, T. Neuroleptic drugs in the management of behavioral symptoms of Alzheimer's disease. Psych Clin North Am 1991; 14: 353–73.CrossRefGoogle ScholarPubMed
137 Teri, L, Borson, S, Kiyak, HA, Yamagishi, M. Behavioral disturbance, cognitive dysfunction, and functional skill. Prevalence and relationship in Alzheimer's disease. J Am Geriatr Soc 1989; 37: 109–16.Google Scholar
138 Swearer, JM, Drachman, DA, O'Donnell, BF, Mitchell, AL. Troublesome and disruptive behaviors in dementia. J Am Geriatr Soc 1988; 36: 784–90.Google Scholar
139 Ryden, MB. Aggressive behavior in persons with dementia who live in the community. Alzheimer's Dis Assoc Disord 1988; 2(4): 342–55.CrossRefGoogle ScholarPubMed
140 Kluver, H, Bucy, P. ‘Psychic blindness’ and other symptoms following bilateral temporal lobectomy in rhesus monkeys. Am J Physiol 1937; 119: 352.Google Scholar
141 Lishman, WA ed. Organic psychiatry. The psychological consequences of cerebral disorder, second edition. Oxford: Blackwell Scientific Publications, 1987: 392.Google Scholar
142 Cummings, JL, Duchen, LW. Kluver-Bucy syndrome in Pick's disease: clinical and pathologic correlations. Neurology 1981; 31: 1415–22.CrossRefGoogle ScholarPubMed
143 Hope, RA, Fairburn, CG. The nature of wandering in dementia: a community-based study. Int J Geriatr Psychiatry 1990; 5: 239–45.CrossRefGoogle Scholar
144 Rubin, EH, Morris, JC, Berg, L. The progression of personality changes in senile dementia of the Alzheimer's type. J Am Geriatr Soc 1987; 35: 721–25.CrossRefGoogle ScholarPubMed
145 Baumgarten, M, Becker, R, Gauthier, S. Validity and reliability of the Dementia Behavior Disturbance Scale. J Am Geriatr Soc 1990; 38: 221–26.CrossRefGoogle ScholarPubMed
146 Hope, RA, Fairburn, CG, Goodwin, GM. Increased eating in dementia. Int J Eating Dis 1989; 8: 111–15.3.0.CO;2-S>CrossRefGoogle Scholar
147 Sanford, JRA. Tolerance of debility in elderly dependants by supports at home: its significance for hospital practice. Br Med J 1975; 3: 471–73.CrossRefGoogle ScholarPubMed
148 Satlin, A, Volicer, L, Ross, V, Herz, L, Campbell, S. Bright light treatment of behavioral and sleep disturbances in patients with Alzheimer's disease. Am J Psychiatry 1992; 149: 1028–32.Google ScholarPubMed
149 Okawa, M, Mishima, K, Shimizu, T et al. Sleep-waking rhythm disorders and their phototherapy in elderly patients with dementia. Jpn J Psychiatry Neurol 1989; 43: 293–95.Google Scholar
150 Rubin, EH, Morris, JC, Storandt, M, Berg, L. Behavioral changes in patients with mild senile dementia of the Alzheimer's type. Psychiatry Res 1987; 21: 55–62.Google Scholar
151 Lawlor, BA, Radcliffe, J, Molechan, SE, Martinez, RA, Hill, JL, Sunderland, T. A pilot placebo-controlled study of trazodone and buspirone in Alzheimer disease. Int J Geriatr Psychiatry 1994; 9: 55–61.Google Scholar
152 Lebert, F, Pasquier, F, Petit, H. Behavioural effects of fluoxetine in dementia of Alzheimer type. Int J Geriatr Psychiatry 1994; 9: 590–91.Google Scholar
153 Rapp, MS, Flint, AJ, Herrmann, N, Proulx, G. Behavioural disturbances in the demented elderly: phenomenology, pharmacotherapy and behavioural menagement. Can J Psychiatry 1992; 37: 651–57.Google Scholar
154 Burns, A. Treatment of non-cognitive features of dementia. In: Levy, R, Howard, R, Burns, A eds. Treatment and care in old age psychiatry. Petersfield: Wrightson Biomedical Publishing Ltd, 1993: 47–57.Google Scholar
155 Morishita, L. Wandering behaviour. In: Cummings, J, Miller, B eds. Alzheimer's disease – treatment and long term management. New York: Marcel Dekker Inc., 1990: 155–76.Google Scholar