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Genetic and genomic factors in aging

Published online by Cambridge University Press:  17 November 2008

J Catania  and
DS Fairweather
J Catania*
Affiliation:
University Hospital of South Manchester
DS Fairweather
Affiliation:
Radcliffe Infirmary, Oxford
*
J Catania, Lecturer and Honorary Senior Registrar, University Hospital of South Manchester, Nell Lane, Manchester M20 8LR, UK.
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Abstract

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Type
Biological gerontology
Information
Reviews in Clinical Gerontology , Volume 1 , Issue 2 , May 1991 , pp. 99 - 111
Copyright
Copyright © Cambridge University Press 1991

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References

1Dublin, LI, Lotka, AJ, Speigelman, M. Length of life, a study of life table, revised edition. New York: Ronald Press, 1949.Google Scholar
2Bell, AG. The duration of life and conditions associated with longevity. A study of the Hyde genealogy. Washington DC, 1918.Google Scholar
3Jalavisto, E. Inheritance of longevity according to Finnish and Swedish genealogies. Am Med Internae Ferniae, 1951; 40: 263–74.Google Scholar
4Pearl, R, Pearl, R De W. The ancestry of the long lived. London: Oxford University Press, 1934.Google Scholar
5Kalmann, FJ, Sander, G. Twin studies on aging and longevity. J Hered 1948; 39: 349–57.CrossRefGoogle Scholar
6McWhirter, ND ed. Guinness book of records, 32nd edition. London: Guinness Books, 1989.Google Scholar
7Hauge, M, Harvard, B, Degnbal, B. Hereditary factors in longevity. In: Garts, SJ ed. Genetics today. Proceedings of the 11th International Congress on Genetics, The Hague. New York: Pergamon, 1963: 280.Google Scholar
8Comfort, A. The biology of senescence, third edition. New York: Elsevier, 1979a.Google Scholar
9Hayflick, L. Prospects of human life extension by genetic manipulation. In: Danon, D, Shock, NW, Marois, M eds. Aging: a challenge to science and society, volume 1. Oxford: Oxford University Press, 1985: 162–79.Google Scholar
10Bayliss, R, Clarke, C, Whitfield, AGW. The female life span. JR Coll Phys (Lond) 1986; 20: 290–93.Google ScholarPubMed
11Tice, RR, Schneider, EL. In vitro aspects of human genetic disorders which feature accelerated aging. Interdisciplinary Topics in Gerontology 1976; 9: 60–68.CrossRefGoogle Scholar
12Hayflick, L. Current theories of biological aging. In: Thorbocke, GJ ed. Biology of aging and development. Faseb monograph, volume 3. New York: Plenum Press, 1975: 11–19.CrossRefGoogle Scholar
13Martin, GM, Ogburn, EC, Sprague, CA. Effects of age on cell division. In: Danon, D, Shock, NW, Marois, M eds. Aging: a challenge to science and society, volume 1. Oxford: Oxford University Press, 1985: 124–35.Google Scholar
14Segal, DJ, McCoy, EE. Studies on Down's syndrome in tissue culture. Growth rates and protein contents of fibroblast cultures. J Cell Physiol 1974; 83: 85–90.CrossRefGoogle ScholarPubMed
15Martin, GM, Sprague, CA, Epstein, CJ. Replicative life span of cultivated human cells. Effects of donor's age, tissue and genotype. Lab Invest 1975; 23: 86–92.Google Scholar
16Strehler, BL. Aging: Concepts and theories. In: Viidik, A ed. Lectures on gerontology. New York: Academic Press, 1982: 1–57.Google Scholar
17Medawar, PB. The uniqueness of the individual. London: Methuen, 1957.CrossRefGoogle Scholar
18Williams, GC. Pleiotropy, natural selection and the evolution of senescence. Evolution 1957; 11: 398–410.CrossRefGoogle Scholar
19Jacob, F, Monod, G. In: Locke, M ed. Cytodifferentiation and macromolecular synthesis. New York: Academic Press, 1963: 30–64a.Google Scholar
20Hart, RW, Setlow, RB. Correlation between deoxyribonucleic acid excision repair and life span in a number of mammalian species. Proc Natl Acad Sci USA 1974; 71: 2169–73.CrossRefGoogle Scholar
21Medvedev, ZhA. Repetition of molecular genetic information as a possible factor in evolutionary changes of life span. Exp Gerontol 1972; 7: 227–38.CrossRefGoogle ScholarPubMed
22Cutler, R. Redundancy of information content in the genome of mammalian species as a protective mechanism determining ageing rate. Mech Ageing Dev 1973; 2: 381–408.CrossRefGoogle Scholar
23Robertson, OH, Wexler, BC. Histological changes in the organs and tissues of migrating and spawning Pacific salmon (genus Oncorhynchus). Endocrinology 1960; 66: 222–39.CrossRefGoogle ScholarPubMed
24Hane, S, Robertson, OH. Changes in the 17-hydroxycorticosteroids accompanying sexual maturation and spawning of the Pacific salmon (Oncorhynchus tshawytscha) and rainbow trout (Salmogairdnerii). Proc Natl Acad Sci USA 1959; 45: 886–93.CrossRefGoogle Scholar
25Robertson, OH. Prolongation of the lifespan of Kokanee salmon (Onorhynchus nerka kennerlyi) by castration before beginning of gonad development. Proc Natl Acad Sci USA 1961; 47: 609–21.CrossRefGoogle Scholar
26Sacher, GA. Molecular versus systemic theories on the genesis of ageing. Exp Gerontol 1968; 3: 265–71.CrossRefGoogle ScholarPubMed
27Diamond, JM. Big-bang reproduction and ageing in male marsupial mice. Nature 1982; 298: 115–16.Google Scholar
28Ellis, HM, Horvitz, HR. Genetic control of programmed cell death in the nematode Caenorhabditis elegans. Cell 1986; 44: 817–29.Google Scholar
29Sacher, GA. Maturation and longevity in relation to cranial capacity in hominid evolution. In: Tuttle, R ed. Primate functional morphology and evolution. The Hague: Mouton, 1975: 417–41.Google Scholar
30Cutler, RG. Evolution of human longevity and the genetic complexity governing aging rate. Proc Natl Acad Sci USA 1975; 72: 4664–68.Google Scholar
31Martin, GM. Genetic syndromes in man with potential relevance to the pathobiology of aging. In: Bergsma, D, Harrison, DE eds. Genetic effects on aging. New York: Alan R Liss, 1978: 5–39 (Birth defects: original article series, volume 14, number 1).Google Scholar
32King, MC, Wilson, AC. Evolution at two levels in humans and chimpanzees. Science 1975; 188: 107–16.CrossRefGoogle ScholarPubMed
33Ruvolo, M, Pilbeam, D. Hominid evolution: molecular and palaeontological patterns. In: Wood, B, Martin, L, Andrews, P eds. Major topics in primate and human evolution. Cambridge: Cambridge University Press, 1986: 157–60.Google Scholar
34Freidmann, DB, Johnson, TE. A mutation in the age-1 gene in Caenorhabditis elegans lengthens life and reduces hermaphrodite fertility. Genetics 1988; 118: 75–86.CrossRefGoogle Scholar
35Munkres, KD, Furtek, C. Linkage of conidial longevity determinant genes in Nuerospora crassa. Mech Ageing Dev 1984; 25: 63–77.CrossRefGoogle Scholar
36Esser, K, Keller, W. Genes inhibiting senescence in the ascomycete Podospora anserina. MGG 1976; 144: 107–10.Google ScholarPubMed
37Goodrick, CL. Life span and the inheritance of longevity of inbred mice. J Gerontol 1975; 30: 257–63.CrossRefGoogle ScholarPubMed
38Francis, AA, Lee, WH, Regan, JD. The relationship of DNA excision repair of ultraviolet induced lesions to the maximum life span of mammals. Mech Ageing Dev 1981; 19: 141–46.Google Scholar
39Kato, H, Harada, M, Tsuchiya, K et al. Absence of correlation between DNA repair in ultraviolet irradiated mammalian cells and life span of the donor species. Jpn J Genet 1980; 55: 99–108.CrossRefGoogle Scholar
40Tice, RR, Setlow, RB. DNA repair and replication in aging organisms and cells. In: Finch, E, Schneider, EL eds. Handbook of the biology of aging. New York: van Nostrand Reinhold, 1985; 173–224.Google Scholar
41Vijg, J, Knook, DL. DNA repair in relation to the aging process. J Am Geriatr Soc 1987; 35: 532–41.CrossRefGoogle ScholarPubMed
42Neary, GJ. Ageing and radiation. Nature 1960; 87: 10–18.CrossRefGoogle Scholar
43Sacher, GA. Effects of X-rays on the survival of Drosophila imagoes. Physiol Zool 1963; 36: 295–311.CrossRefGoogle Scholar
44Clark, AM, Bertrand, HA, Smith, RE. Life span differences between haploid and diploid males of Habrobracon serinopae after exposure as adults to X-rays. Am Nat 1963; 97: 203–208.CrossRefGoogle Scholar
45Hoehn, H, Bryant, EM, Martin, GM. The replicative life-span of euploid hybrids derived from short-lived and long lived human skin fibroblast cultures. Cytogenet Cell Genet 1978; 93: 282–95.CrossRefGoogle Scholar
46Gupta, RS, Senescence of cultured human diploid fibroblasts. Are mutations responsible? J Cell Physiol 1980; 103: 209–16.CrossRefGoogle ScholarPubMed
47Thompson, KVA, Holliday, R. The longevity of diploid and polyploid human fibroblasts. Exp Cell Res 1978; 112: 281–87.CrossRefGoogle ScholarPubMed
48Holliday, R, Kirkwood, TBL. Prediction of somatic mutation and mortalisation theories of cellular aging are contrary to experimental observations. J Theoret Biol 1981; 93: 627–42.CrossRefGoogle Scholar
49Fairweather, DS. Classical genetic mutations or eipmutations in aging? In: Grimley Evans, J, Caird, FI eds. Advanced geriatric medicine 7. Bristol: Wright, 1988: 171–86.Google Scholar
50Harman, D. Aging: a theory based on free radical and radiation chemistry. J Gerontol 1956; 11: 298–300.CrossRefGoogle ScholarPubMed
51Cutler, RG. Antioxidants and longevity of mammals. In: Woodhead, AD, Blackett, AD, Hollander, A eds. Molecular biology of aging. New York: Plenum Press, 1985.Google Scholar
52Campbell, SD, Hilliker, AJ, Phillips, JP. Cytogenetic analysis of the cSOD microregion in Drosophila melanogaster. Genetics 1986; 112: 205–15.Google Scholar
53Arkling, R, Dudas, SP. Review of genetic investigations into the aging processes of Drosophila. J Am Geriatr Soc 1989; 37: 757–73.CrossRefGoogle Scholar
54Cathcart, R, Schiewers, E, Saul, RL, Ames, BN. Thymine glycol and thymidine glycol in human and rat urine: a possible assay for oxidative DNA damage. Proc Natl Acad Sci USA 1984; 81: 5633–37.Google Scholar
55Cutler, RG. Longevity is determined by specific genes: testing the hypothesis. In: Adelman, RC, Roth, GS eds. Testing the theories of aging. Boca Raton: CRC Press, 1982: 25–114.Google Scholar
56Ono, T, Cutler, RG. Age-dependent relaxation of gene expression: increase of endogenous murine leukaemia virus-related and globin-related RNA in the brain and liver of mice. Proc Natl Acad Sci USA 1978; 75: 4431–35.CrossRefGoogle Scholar
57Mays-Hoopes, LL, Brown, A, Huang, RCC. Methylation and rearrangement of mouse intracisternal A particle genes in development, aging and myeloma. Mol Cell Biol 1983; 3: 1371–80.Google ScholarPubMed
58Cattanach, BM. Position effect variegation in the mouse. Genet Res 1974; 23: 291–306.CrossRefGoogle ScholarPubMed
59Wareham, KA, Lyon, MF, Glenister, PH, Williams, ED. Age-related reactivation of an X-lined gene. Nature 1987; 327: 725–27.CrossRefGoogle Scholar
60Wilson, VL, Jones, PA. DNA methylation decreases in ageing but not in immortal cells. Science 1983; 220: 239–46.CrossRefGoogle ScholarPubMed
61Fairweather, DS, Fox, M, Margison, GP. DNA hypomethylation: a new theory of aging. Clin Sci 1985; 69 (suppl 12): 53–54.CrossRefGoogle Scholar
62Fairweather, DS, Fox, M, Margison, GP. In vitro life span of MRC-5 fibroblasts is shortened by 5-azacytidine induced demethylation. Exp Cell Res 1987; 168: 153–59.CrossRefGoogle Scholar
63Orgel, LE. The maintenance of the accuracy of protein synthesis and its relevance to ageing. Proc Natl Acad Sci USA 1963; 49: 517–21.CrossRefGoogle ScholarPubMed
64Gershon, H, Gershon, D. Detection of inactive molecules in aging of organisms. Nature 1970; 227: 1214–17.CrossRefGoogle Scholar
65Reiss, U, Rothstein, M. Age-related changes in isocitrate lyase from the free-living nematode, Turbatrix aceti. J Biol Chem 1975; 250: 826–30.CrossRefGoogle ScholarPubMed
66Reiss, U, Rothstein, M. Heat labile isozymes of isocitrate lyase from aging Turbatrix aceti. Biochem Biophys Res Commun 1974; 61: 1012–16.CrossRefGoogle ScholarPubMed
67Hardt, H, Rothstein, M. Altered phosphoglycerate from old rat muscle shows no change in primary structure. Biochim Biophys Acta 1976; 831: 13–21.CrossRefGoogle Scholar
68Rothstein, M. Biochemical approaches to aging. New York: Academic Press, 1982: 243–344.Google Scholar
69Tollefsbol, TO, Cohen, HJ. Role of protein molecular and metabolic aberrations in aging, in the physiologic decline of the aged and in age-associated diseases. J Am Geriatr Soc 1986; 34: 282–94.CrossRefGoogle ScholarPubMed
70Simic, MG, Grossman, L, Upton, AC eds. Mechanisms of DNA damage and repair: implications for carcinogenesis and risk assessment (Basic life sciences series, volume 38). New York: Plenum Press, 1985.Google Scholar
71Fairweather, DS, Evans, JG. Ageing. In: Cohen, RD, Alberti, KCMM, Lewis, B, Denman, AM eds. The metabolic and molecular basis of acquired disease. Eastbourne: Ballière Tindall, 1990.Google Scholar
72Holliday, R. DNA methylation and epigenetic inheritance. Philos Trans R Soc Lond [Biol] 1990; 326: 329–38.Google ScholarPubMed