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Disorders of the liver, gallbladder and pancreas

Published online by Cambridge University Press:  17 November 2008

Ian R Crossley*
Affiliation:
Cirencester Hospital, UK
*
Dr Ian R Crossley, Cirencester Hospital, The Querns, Tetbury Road, Cirencester, Gloucestershire GL7 1UY, UK.

Abstract

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Type
Clinical geriatrics
Copyright
Copyright © Cambridge University Press 1991

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References

1Wynne, HA, Cope, LH, Mutch, E, Rawlins, MD, Woodhouse, KW, James, OFW. The effect of age upon liver volume and apparent liver blood flow in healthy man. Hepatology 1989;; 9: 297–30.CrossRefGoogle ScholarPubMed
2Marchesini, G, Bianchi, GP, Fabbri, A et al. Synthesis of urea after a protein-rich meal in normal man in relation to ageing. Age Ageing 1990; 19: 410.Google Scholar
3Brouwer, A, Horan, MA, Barelds, KG, Knook, DL. Cellular ageing of the reticuloendothelial system. Arch Gerontol Geriatr 1986; 5: 317–24.CrossRefGoogle Scholar
4Einarsson, K, Nilsell, K, Leigd, B, Angelin, B. Influence of age on secretion of cholesterol and synthesis of bile acids by the liver. N Engl J Med 1985; 313: 277–82.CrossRefGoogle ScholarPubMed
5Laugier, R, Boustiere, C, Hubert, J, Sarles, H. Evolution de la secretion pancreatique exocrine en fonction de l'age. Gastroenterol Clin Biol 1985; 25: 203–16.Google Scholar
6Wilkinson, GR, Shand, DG. A physiological approach to hepatic drug clearance. Clin Pharmacol Ther 1975; 18: 377–90.CrossRefGoogle ScholarPubMed
7Blaschke, TF. Protein binding and kinetics of drugs in liver disease. Clin Pharmacokinet 1977; 2: 3244.CrossRefGoogle Scholar
8Woodhouse, AW, James, OFW. Hepatic drug metabolism and ageing. Br Med Bull 1990; 46: 2235.CrossRefGoogle ScholarPubMed
9O'Malley, K, Krooks, J, Duke, E et al. Effect of age and sex on human drug metabolism. Br Med J 1971; 3: 607609.Google Scholar
10Posner, J, Danhof, M, Tewnissen, MWE et al. The disposition of anti-pyrine and its metabolites in young and elderly healthy volunteers. Br J Clin Pharmacol 1987; 24: 5155.Google Scholar
11Swiff, CG, Homeida, M, Halliwell, M et al. Antipyrine disposition and liver size in the elderly. Eur J Clin Pharmacol 1978; 14: 149–52.Google Scholar
12Greeblatt, DJ, Sellers, EM, Shader, RI. Drug disposition in old age. N Engl J Med 1982; 306: 1081–87.Google Scholar
13Kato, R, Vassanilli, P, Frontino, G. Variation in the activity of liver microsomal drug metabolising enzymes in rats in relation to age. Biochem Pharmacol 1964; 12: 1037–51.CrossRefGoogle Scholar
14Wynne, HA, Mutch, E, James, OFW, Wright, P, Rawlins, MD, Woodhouse, KW. The effect of age on the affinity of microsomal mono-oxygenase enzymes for substrate in human liver. Age Ageing 1988; 17: 401405.Google Scholar
15Sutter, MA, Wood, WG, Williamson, LS et al. Comparison of the hepatic mixed function oxidase system of young adult and old non-human primates (Macaca nenestrina). Biochem Pharmacol 1985; 34: 2983–87.Google Scholar
16Maloney, AG, Schmucker, DL, Vessey, DS et al. The effects of ageing on the hepatic microsomal mixed-function oxidase system of male and female monkeys. Hepatology 1986; 6: 282–87.CrossRefGoogle ScholarPubMed
17Woodhouse, KW, Mutch, E, Williams, EM et al. The effect of age on pathways of drug metabolism in the human liver. Age Ageing 1984; 13: 328–34.Google Scholar
18Marchesini, G, Bua, V, Brunori, A et al. Galactose elimination capacity in liver volume in ageing man. Hepatology 1988; 8: 1979–83.Google Scholar
19Wallace, SM, Verbeek, RK. Plasma protein binding of drugs in the elderly. Clin Pharamacokinet 1987; 12: 4172.Google Scholar
20Saint-Marc Girardin, MF, LeMiner, M, Alpero-Vilch, A et al. Computer aided selection of diagnostic tests in jaundiced patients. Gut 1985; 26: 961–67.CrossRefGoogle ScholarPubMed
21Chapman, RW. Primary sclerosing cholangitis. J Hepatol 1985; 1: 179–86.Google Scholar
22Alter, HJ, Deinstag, JL. The evolving spectrum of non-A non-B hepatitis. In: Chisar, FV ed. Advances in hepatitis research. New York: Masson, 1984: 281–92.Google Scholar
23Goodson, JD, Taylor, PA, Campion, EW, Richter, JM, Wands, J. The clinical course of acute hepatitis in elderly patients. Arch Intern Med 1982; 142:1485–98.CrossRefGoogle Scholar
24Mackay, IR, Wood, IJ. Lupoid hepatitis: a comparison of 22 cases with other types of chronic liver disease. Q J Med 1962; 31: 485507.Google Scholar
25Read, AE, Sherlock, S, Harrison, CV. Active juvenile cirrhosis considered as part of a systemic disease and the effect of corticosteroid therapy. Gut 1963; 4: 378–93.CrossRefGoogle ScholarPubMed
26Cook, CG, Mulligan, R, Sherlock, S. Controlled prospective trial of corticosteroid therapy on active chronic hepatitis. Q J Med 1971; 40: 159–85.CrossRefGoogle Scholar
27Solloway, RD, Summerskill, WHJ, Baggenstoss, AH et al. Clinical biochemical and histological remission of severe chronic active liver disease. A controlled study of treatments and early prognosis. Gastroenterology 1972; 63: 820–33.Google Scholar
28Wang, KK, Czaja, AJ. Corticosteroid treatment of hepatitis B surface antigen negative chronic active hepatitis in post-menopausal women – a retrospective analysis. Gastroenterology 1989; 97: 1288–93.CrossRefGoogle Scholar
29Israel, Y, Videla, L, Bernstein, J. Hypermetabolic state after chronic ethnol consumption. Hormonal interrelations and pathogenic implications. Fed Proc 1975; 34: 2052–59.Google Scholar
30Saunders, JB, Haines, A, Portaman, B et al. Accelerated development of alcoholic cirrhosis in patients with HLA-B8. Lancet 1982; i: 1381–84.Google Scholar
31Crossley, IR, Neuberger, J, Saunders, JB, Davies, M, Williams, R. The role of ethnol metabolism in the generation of new antigenic determinents on liver cells. Gut 1986; 27: 186–89.CrossRefGoogle Scholar
32Bridgewater, R, Leigh, S, James, OFW, Potter, JF. Alcohol consumption and dependence in elderly patients in an urban community. Br Med J 1987; 295: 884–85.Google Scholar
33Woodhouse, KW, James, OFW. Alcoholic liver disease in the elderly: presentation and outcome. Age Ageing 1985; 14: 113–18.Google Scholar
34Potter, JF, James, OFW. Clinical features and prognosis of alcoholic liver disease in respect of advancing age. Gerontology 1987; 33: 380–87.Google Scholar
35Orrego, H, Kalant, H, Israel, Y et al. Effect of short term therapy with propylthiouracial in patients with alcoholic liver disease. Gastroenterology 1979; 76: 105–15.Google Scholar
36Halle, P, Par, P, Kapstein, E et al. Double blind controlled trial of propylthiouracial in patients with severe acute alcoholic hepatitis. Gastroenterology 1982; 82: 925–31.CrossRefGoogle Scholar
37Porter, HP, Simon, FR, Hope, CE et al. Corticosteroid therapy in severe alcoholic hepatitis; a double blind drug trial. N Engl J Med 1971; 284: 1350–55.Google Scholar
38Crossley, IR, Williams, R. Nutrition and the liver and pancreas. Curr Opin Gastroenterol 1987; 3: 321–25.CrossRefGoogle Scholar
39Beswick, DR, Boyer, JL. Primary biliary cirrhosis. Hepatology 1984; 4: 2932S.Google Scholar
40Christensen, E, Crowe, J, Doniach, D et al. Clinical pattern and course of disease in primary biliary cirrhosis based on analysis of 236 patients. Gastroenterology 1980; 78: 236–46.Google Scholar
41Shepherd, AN, Bedford, GJ, Hill, A, Bouchier, IAD. Primary biliary cirrhosis, dark adaptology, electro-oculography, and vitamin A state. Br Med J 1984; 289: 1484–85.CrossRefGoogle Scholar
42Roll, J, Bowyer, JL, Barry, D, Klatskin, G. The prognostic importance of clinical and histological features in asymptomatic and symptomatic primary biliary cirrhosis. N Engl J Med 1983; 308: 17.Google Scholar
43Lehman, AB, Bassendine, MF, James, OFW, Primary biliary cirrhosis – a different disease in the elderly? Gerontology 1985; 31: 186–94.CrossRefGoogle Scholar
44Berg, PA, Lindenborn-Fotinos, J, Klein, R, Kloppel, W. ATPase-associated antigen (M2); antigen for serological diagnosis of primary biliary cirrhosis. Lancet 1982; ii: 1423–27.Google Scholar
45Mann, M, Meyer zum Buschenfelde KH. A mitochondrial antigen antibody system in cholestatic liver disease detected by radio-immuno assay. Hepatology 1982; 3: 1.Google Scholar
46Heathcote, J, Ross, A, Sherlock, S. A prospective control trial of azathioprine in primary biliary cirrhosis. Gastroenterology 1976; 70: 656–60.CrossRefGoogle ScholarPubMed
47Matloff, DS, Alpert, E, Resnick, RH, Kaplan, MM. A prospective trial of D penicillamine in primary biliary cirrhosis. N Engl J Med 1982; 306: 319–26.CrossRefGoogle ScholarPubMed
48Epstein, O, Lee, RJ, Boss, AM et al. D penicillamine treatment improves survival in primary biliary cirrhosis. Lancet 1981; i: 1275–77.Google Scholar
49Poupon, R, Poupon, RE, Calmus, Y, Chretien, Y, Ballet, F, Darnis, F. Is ursodeoxycholic acid an effective treatment for primary biliary cirrhosis? Lancet 1987; i: 834–36.Google Scholar
50Bachs, L, Pares, A, Elena, M, Piera, C, Rodes, J. Comparison of rifampicin with phenobarbitone for treatment of pruritus in biliary cirrhosis. Lancet 1989; i: 574–76.Google Scholar
51Thornton, JR, Heaton, KW, Espiner, HJ, Eltringham, WK. Empyema of the gall bladder – reappraisal of a neglected disease. Gut 1983; 24: 1183–85.Google Scholar
52Williamson, BWA, Simpson, CJ, McLatchie, G et al. Prospective randomised trial of early versus delayed surgery for acute biliary tract disease. Gut 1984; 25: 1140–41.Google Scholar
53Sandier, RS. Biliary tract surgery in the elderly. J Gen Intern Med 1987; 2: 149–54.Google Scholar
54Abate, MA. Medical management of cholesterol stones. Drug Intell Clin Pharm 1986; 20: 106–15.Google Scholar
55Northfield, PC, Maudgal, DP. Oral medical therapy. In: Bateson, MC ed. Gallstone disease and its management. Lancaster: MTP Press, 1986: 203–27.Google Scholar
56Houghton, PJW, Donaldson, LA. Elective biliary surgery – a safe procedure. Geriatric Med 1983; 13: 814–16.Google Scholar
57Sackmann, M, Delius, M, Sauerbruch, T et al. Shockwave lithotripsy of gallbladder stones. N Engl J Med 1988; 318: 391–97.Google Scholar
58McSherry, CF, Glen, F. The incidence and causes of death following surgery for non malignant biliary tract disease. Ann Surg 1980; 191: 271–75.CrossRefGoogle Scholar
59Ingoldby, CJH, El-saadi, J, Hall, RI, Denyer, ME. Late results of endoscopic sphincterotomy for bile duct stones in elderly patients with gall bladders in situ. Gut 1989; 30: 1129–31.Google Scholar
60Cotton, PB. Endoscopic management of bile duct stones (apples and oranges). Gut 1984; 25: 587–97.Google Scholar
61Carick, J, Doust, B, Coleman, M, Byrnes, D, Hugh, TB, Barody, TJ. Methyl-tertiary-butyl ether cholelitholysis of calculi in the gall bladder and bile ducts. Aust N Z J Med 1987; 17: 435–40.Google Scholar
62Corfield, AP, Cooper, NJ, Williamson, RCN. Acute pancreatitis: a lethal disease of increasing incidence. Gut 1985; 26: 724–29.CrossRefGoogle ScholarPubMed
63Sarles, H, Sarles, JC, Muratore, R, Guien, C. Chronic inflammatory cirrhosis of the pancreas, an autonomous pancreatic disease. Am J Dig Dis 1961; 6: 17.Google Scholar
64Okazaki, Y, Yamamoto, Y, Kagiyama, S et al. Pressure of papillary zone and pancreatic main duct in patients with chronic pancreatitis in the early state. Scand J Gastroenterol 1988; 23: 501506.Google Scholar
65Cooper, MJ, Williamson, RCN. Drainage operations in chronic pancreatitis. Br J Surg 1984; 71: 761–66.CrossRefGoogle ScholarPubMed
66Soehendra, N, Grimm, H, Schreiber, H. Endoscopic trans-papillary drainage of the pancreatic duct in chronic pancreatitis. Dtsch Med Wochenschr 1986; 111: 727–31.Google Scholar
67White, TT. Pain relieving procedures in chronic pancreatitis. Contemp Surg 1983; 22: 4352.Google Scholar
68Mitty, HA, Efremidis, SC, Yeah, HC. Impact of fine needle biopsy on management of patients with carcinoma of the pancreas. AJR 1981; 137: 119–21.Google Scholar
69Neiman, JL, Holmes, FF. Accuracy of diagnosis of pancreatic cancer decreases with increasing age. J Am Gerontol Soc 1989; 37: 97100.Google Scholar
70Andersen, JR, Sorensen, SM, Kruse, A, Rokkjaer, M, Matzen, P. Randomised trial of Endoscopic endoprosthesis versus operative by-pass in malignant obstructive jaundice. Gut 1989; 30: 1132–35.Google Scholar