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Diabetes in later life

Part of: Bespoke shallow archive Weizmann

Published online by Cambridge University Press:  22 February 2006

Terence J. Aspray
Terence J. Aspray
Affiliation:
Sunderland Royal Hospital and Newcastle University, UK
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Extract

Type 2 diabetes is a chronic progressive condition with a prevalence which rises with age. Its origins are believed to be multifactorial, and include genetic effects and environmental interactions, which may start in the uterus (with an association with low birth weight) and early developmental plasticity, resulting in compensatory growth through childhood and a tendency to abnormal glucose tolerance in adult life. The consequences are multi-systemic, with a combination of microvascular and macrovascular disease affecting multiple organs of the body. There is a high level of morbidity and mortality, typically accruing through adult life and into older age.

Type
Clinical geriatrics
Information
Reviews in Clinical Gerontology , Volume 15 , Issue 1 , February 2005 , pp. 27 - 38
Copyright
© 2006 Cambridge University Press

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